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Osteoporosis
Chronic metabolic disease from bone demineralization causing fragile bones and increased risk of fracture
Osteomalacia
Soft bone from vitamin D deficiency; at risk for fractures
Osteopenia
Low bone density, not yet severe enough to be osteoporosis
Pathophysiology of Osteoporosis
Bone resorption increases as formation slows; Primary- psotmenopasual; dec. testosterone
secondary- prolonged steroid/antithyroid/antacids/antiseizure meds
Risk factors for Osteoporosis
Female, postmenopausal, age >65, white/Asian, smoking, alcohol, low Ca/Vit D, corticosteroids.
Manifestations of Osteoporosis
possibly asymptomatic
Back pain after lifting, bending, stooping
increased pain w palpatation
vertebral fracture
height loss
kyphosis.
Diagnosis of Osteoporosis
DXA scan; T-score ≤ -2.5 diagnostic.
Lifestyle recommendations to decrease risk of Osteoporosis
1200 mg calcium/day, Vit D3 800-1000 IU/day, weight-bearing exercise, limit alcohol & coffee, stop smoking.
Calcium supplementation
MOA: increase body's available Ca+
SE: hypercalcemia (GI upset, renal dysfunc, lethargy, dysrhythmias)
admin: NO MORE than 600 mg/dose
carbonate with meals; citrate if on PPI.
Vitamin D3
Essential for Ca+ absorption in intestines.
SE: toxicity
Bisphosphonates (-nate)
Inhibit osteoclast mediated bone resorption;
DO NOT GIVE: existing hypercalcemia or hyperparathyriod
SE: esophagitis, muscle pain, eye issues
ADMIN: take with water NOT food immediately in morning, sit upright 30 min.
Recombinant DNA Parathyroid Hormone: Teriparatide
Stimulates osteoblasts
used for high fracture risk.
DO NOT USE: bone metastases, hx of skeletal cancer, inc. risk of bone cancer
SE: nausea, headache, back pain, leg cramps
ADMIN: pen expires 28 days after 1st injection, store pen COLD
Pathophysiology of Osteoarthritis
progressive deterioration of articular cartilage
Manifestations of Osteoarthritis
joint Pain worsens with use, relieved by rest; crepitus; stiffness; nodes in hands.
Management of Osteoarthritis
meds
heat/cold, weight loss, bracing, PT, balanced activity/rest.
medications for osteoarthritis
Rheumatoid Arthritis
Autoimmune inflammatory disease causing synovial joint and connective tissue destruction.
Manifestations of Rheumatoid Arthritis
Local: Morning stiffness >30 min, symmetrical joint pain/swelling, deformities
systemic: fatigue, fever, weakness, anorexia
Medications for Rheumatoid Arthritis
NSAIDs- pain/inflammation SE: stomach upset, heart burn, headaches, GI bleeds
glucocorticoids-anti-inflammatory & immunosuppresion SE weight gain, mood changes, GI upset, inc BP/BG
DMARDs (methotrexate, hydroxychloroquine, sulfasalazine) slow degenerative effects SE: infection, immunosuppression, anemia, hepatotoxicity, ecchymosis *frequent neutrophil/WBC/platelet labs
Management of Rheumatoid Arthritis
preserve function, joint protective devices, ROM, exercise program, heat/cold therapy, paraffin bath
Preoperative care for Joint Replacement
Infection screen
medication adjustments
assistive device/precaution teaching
Postoperative care for Hip Replacement
ABduction pillow
no internal rotation
no flexion >90°
raised toilet seat.
Postoperative care for Knee Replacement
Immobilizer, early PT, ROM goal 90°, pain management
strain vs sprain
Strain = muscle/tendon stretching
sprain = ligament injury
S/S- similar for both= pain, edema, decreased function, bruising
RICE & tylenol/NSAIDS
colles' fracture
result of fall onto an outstretched hand
s/s of fractures
pain and tenderness
edema
ecchymosis
pallor
obvious deformity
decreased ROM of joint or distal to joint
classification of fractures
position of bone ends:
displaced = bone ends separated, non-displaced= bone end still together
completeness of break: incomplete= bone cracks/bends but doesn't completely break
complete= break completely through bone
direction of break:
oblique, transverse, spiral
communication w external environment:
closed= under skin
open= bone outside skin
traumatic
pathologic= underlying weakness of bone structure
Salter-Harris Fracture
injury or fracture through growth plate
most common type of fracture in children
if not treated properly can interfere w growth
Healing stages of fractures
Hematoma → fibrocartilaginous callus formation → bony callus → bone remodeling.
fracture management
acute: neurovascular assessments
splint fracture site
remove sources of contamination
pain relief and reduce swelling
Reduction methods
realignment of bone fragments
Closed = realignment without surgery
open= surgery
Fixation
immobilization to maintain realignment of fracture site
traction
internal (devices like plates, screws, or rods surgically placed inside the body to hold the bone together)
external (External fixation uses pins and a rigid frame outside the body to stabilize a bone)
cast
Cast care
Neurovascular checks; elevate; ice first 24 hrs; prevent DVT (ROM, heparin)
no objects inside cast.
Traction
Skin- usually intermittent, no more than 10 lbs
skeletal- traction applied continuously, heavier weights can be used alignment; pain management; prevent complications.
Neurovascular Assessment
5 P's: Pain, Pulse, Pallor, Paresthesia, Paralysis.
Complications of Fractures
Infection, VTE, fat embolism (resp distress + petechiae),
compartment syndrome
s/s- early= severe pain unrelieved by meds
late=pallor, pulselessness, paralysis
treatment: fasciotomy to relieve pressure
Pelvic and Hip Fractures
Risk for hemorrhage;
extracapsular= ORIF
intracapsular= arthroplasty often required.
post op care from pelvis/hip fracture
monitor vs
watch for s/s of hemorrhage
anticoagulants
manage pain
encourage coughing/deep breathing
perform nv assessment of distal extremity
Amputation Care
Causes: Diabetes, PAD, trauma;
postop: rigid dressing, prevent contractures (prone lying), phantom limb pain management.