Tumor
clump of cells with no purpose
Benign tumor
normal cells duplicating fast
malignant tumor
cancer cells duplicating fast
Big tumor
less blood and nutrients
metastasis
spread of cancer cells
radiation treatment
high energy x-ray kills any cell in its path
chemotherapy
poisoning medication
Diploid cell
body cells in pairs
Haploid cell
individual sex cells
Cell cycle
when cells grow and divide to make more
G1 phase
cell begins growing
G0
a resting phase when the cell cant copy
Synthesis phase
cell is copied
G2 phase
cell continues growing after synthesis
Prophase
(1) DNA “spaghetti” converts into chromosomes
Metaphase
(2) chromosomes line up in the middle
anaphase
(3) sister chromatins (connected chromosomes) break apart
Telophase
(4) 2 nuclei are formed
cytokinesis
2 cells are made, cycle is over
miosis
making of SEX cells
mitosis
making of BODY cells
apoptosis
destroy cells process
Checkpoints in the cell cycle
resting phases that stimulate or prevent cell division until conditions are met
differentiates
when a cell stops dividing and exits the cycle
cell cycle regulators
proteins that control the progression of a cell, can either stimulate or prevent progression in the cycle
Sex-linked RECESSIVE
affected moms and sons
Sex-linked DOMINANT
affected dads and daughters
meiosis
process of creating egg and sperm (gametes)
specialized body cell
only job is to go through meiosis
Products of meiosis
4 different haploid gametes
P1 (MEI)
chromosomes form tetrads
tetrads
chromosomes from mom and dad linked
crossing over
tetrads trading sections of DNA
M1 (MEI)
chromosomes line up with tetrad pairs
A1 (MEI)
tetrads pull apart
T1 (MEI)
nuclei form
C1 (MEI)
cells turn haploid
proto-oncogenes
gas pedals of the cell process
tumor supressor genes
brake pedals of the cell process
Frameshift insertion
extra letter shifts codons
nonsense mutation
early stop codon
silent mutation
wrong DNA, same protein
substitution
wrong letter no shift
frameshift deletion
letter deletes shifts codons
Hayflick limit
# of times a cell can go through the cell cycle
Telomeres
caps on chromosomes, become shorter over time
telomerase protein
protein that creates telomeres that stops producing after birth
Cells hayflick limit
healthy cells can divide 50 times until apoptosis