Microbiology: Gram Negative Cocci

Neisseria gonorrhea characteristics

use glucose

grow on Thayer-Martin chocolate agar

oxidase positive

Neisseria gonorrhea virulence factors

opacity proteins - binding on different cell types

pili and LPS - antigenic variation

Neisseria gonorrhea clinical significance

STI

Ophthalmia neonatorum

Neisseria gonorrhea antibiotics

ceftriaxone

Neisseria meningitidis characteristics

use glucose and maltose

polysaccharide capsule

serogroup and serotype for ID

oxidase positive

Neisseria menigitidis virulence factors

capsule - antiphagocytic

gonococcal lipopolysaccharides - antigenic variation

pili - mediate attachment

Neisseria menigitidis clinical significance

meningitis with a purpuric rash

septicemia

transmitted by respiratory droplets

Serogroups B and C are most predominant

Neisseria menigitidis antibiotics

3rd gen cephalosporin