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RNA processing step two
introns are spliced out by spliceosome. exons connect to each other.
RNA processing step one
5’ cap methyl group, ribosome binds at cap and then slides down for translation.
in prokaryotes, transcription and translation are:
coupled
Transcription
copying part of dna into rna, promoter determines which strand to copy, template strand (3’-5’) complementary to rna. (TATA boxes)
RNA polymerase adds nucleotides-part of promoter region.
rRna
makes the proteins
Trna
transfer; takes amino acids to make proteins
mrna
messenger, takes dna into cytoplasm
Why do RNA’s fold into tertiary structures
hydrogen bonds
Centromere
Holds chromosomes together
Replication site
allows for the gene to be expressed
Telomere
serves as a protective cap, shortens with each division
Epigenetic changes are?
heritable; genetic markers
Epigenetics Example
Queen vs Worker Bees (Same DNA, different histone modifications)
histone tails
acetyl+ Methyl groups
loosely packaged ___ gene expression
more; euchromatin
tightly packaged ___ gene expression
less; heterocromatin
epigenetics dogma
packaging influences gene expression
histones
positive charged amino acids
nucleosome
dna wrapped around histone proteins packaging ratio 7:1
levels of dna packaging
dna duplex, nucleosome, chromatin, looped domains, chromosomes, dna
Cytosine and Guanine have ___ Hydrogen bonds
3
Adanine and Thymine have ___ hydrogen bonds
2
steps of the scientific method
exploration and discovery
testing ideas
community analysis and feedback
theory
explanation of the natural world based on evidence
earths crust has what two elements?
oxygen and silicon
human body consists mainly of what two elements
oxygen,carbon,hydrogen
are viruses made of cells
no
central dogma
dna is transcribed to rna transcripted to proteins
when simple compounds are combined into complex molecules the entropy inside the cell ___
decreases
when energy is released as heat, what happens to the entropy
it increases
first law of thermodynamics
energy is neither created nor destroyed
second law of thermodynamics
degree of disorder tends to increase
disorder in a system
entropy
plasma membrane
seperates the living material within the cell from the nonliving enviornment around it
metabolism
chemical reactions by which cells convert energy from one form to another and build and break down molecules
ATP
stored energy in chemical form
how does a virus spread
hijacks a cell
genetic variation
difference in genetic material that is transmitted from parent to offspring
in an atoms nucleus
protons and neutrons
ion
charged atom
loss of an electron
cation
gain of an electron
anion
further from the nucleus electrons are the ____ stable they are
less
energy levels are called
shells
carbon has __ valence electrons
4
unique about rows in periodic table
same number of shells and orbitals
unique about colums of the periodic table
same number of valence electrons
why is carbon so versatile
it can form 4 bonds
isomer
same atom different arrangements
function is dependent on
structure
what is needed to break a covalent bond
enzyme
what is needed to break non covalent bonds
heat
partial charge of oxygen in water is
negative
partial charge of hydrogen in water is
positive
polar molecule
has a positive and negative side
bigger difference in electronegativity
more polar
hydrogen bond
weak attraction between electronegative atom and a hydrogen bonded to an electronegative atom
two water molecules form
hydrogen bonds
when water freezes it becomes
more dense
why can water resist temperature changes
hydrogen bonds
why does water not evaporate easily
high boiling point
water is a ____ solvent
universal
why is water a universal solvent
polarity allows for other polar or fully charged molecules to dissolve in water
what makes water cohesive
hydrogen bonds combined are strong and allow for surface tension
van der waals forces
weak attraction between atoms due to electron asymmetries
importance of van der waals forces
hold fatty acids together
ph=
-log[H+]
ph and H+ are ______ related
inversely
1 mole=
6.022 × 10²³
4 classes of macromolecules
proteins, nucleic acids,lipids,sugars
proteins are _____ made up of ____
polymers, monomers
monomer of proteins
amino acids
polymer
protein monomers covalently linked to each other
monomers of nucleic acids
nucleotides
two types of nucleic acids
DNA and RNA
3 types of liquids
fats and oils, steroids,phospholipids
polymer of sugars
polysaccharides
monomer of sugars
monosaccharides
function of sugar
store energy and structure
theory of chemical evolution creators
haldane and oparin
theory of chemical evolution
biological matter formed from atmospheric gases, water vapor, energy
urey and miller experiment
mini ocean plus energy created amino acids
what did the urey and miller experiment create
amino acids, formaldehyde, hydrogen cyanide
hydrophobic molecules are always
non polar
peptide bond
carboxyl group joined with nitrogen
two types of dna bases
pyrimidine and purine
pyrimidines
cytosine,thymine,uracil
purines
adenine and guanine
glyoside bonds
monosacharides that are attached to each other by covalent bonds
triacylglycerol
lipid used for energy storage
fatty acid
long chain of carbon atoms attached to a carboxyl group
what makes a lipid saturated
double bonds
what makes a lipid unsaturated
C-C double bonds
griffith experiment
virulent and nonvirulent bacteria was ejected into mice
what was discovered from griffith experiment
dna can transfer biological charachteristics from one organism to another
discovered 3 dimensional structure of dna
watson,crick,franklin
what is a nucleotide made of
phosphate group, deoxyribose sugar, nitrogenous base
bonds between sugar and phosphate
phosphodiester
dna has a net _____ charge
negative
what types of bonds hold the two strands of DNA together
hydrogen bonding