Chapter 3: Cell Differentiation

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role of BRCA genes without mutations

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repair DNA and prevent uncontrolled cell growth

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BRCA gene that is associated with a higher risk of breast cancer and ovarian cancer and is also linked to other cancers including pancreatic and prostate.

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BRCA1

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34 Terms

1

role of BRCA genes without mutations

repair DNA and prevent uncontrolled cell growth

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2

BRCA gene that is associated with a higher risk of breast cancer and ovarian cancer and is also linked to other cancers including pancreatic and prostate.

BRCA1

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3

BRCA gene that is less severe but increases the risk for breast cancer, ovarian cancer, pancreatic, prostate and male breast cancer

BRCA2

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4

type of stem cell that has the ability to develop into any cell type or complete organism

totipotent

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5

type of stem cell that has the ability to develop into any cell type within an already existing organism excluding extra-embryonic tissue

pluripotent

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6

type of stem cell that can differentiate into any cell types within a specific lineage of tissue

multipotent

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7

type of stem cell that can produce a limited number of cell types within a specific lineage of tissue

oligopotent

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8

type of stem cell that can differentiate into only one specific cell type

unipotent

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9

components of the ectoderm

skin, nervous system

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10

components of the mesoderm

muscles, blood, bones

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11

components of the endoderm

internal organs

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12

three types of stem cells

embryonic, fetal, adult

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13

three types of stem cells that are found in adult bone marrow

hematopoietic, endothelial, mesenchymal

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14

process of blood cell formation that occurs primary in bone marrow

hematopoiesis

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15

stem cell responsible for hematopoiesis

hematopoietic

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16

two cells that emerge from hematopoietic stem cels

myeloid progenitor, lymphoid progenitor

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17

cell that is derived from a myeloid progenitor that functions in blood clots and wound healing

thrombocytes

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18

cell that is derived from a myeloid progenitor that functions in delivering oxygen to tissues and returning carbon dioxide to lungs

erythrocytes

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19

cell that is derived from a myeloid progenitor that functions in immune response with the tissue to elicit a localized immune response

mast cell

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20

cell that is derived from a myeloconblast that functions in response to allergic reactions and inflammation throughout the blood by release histamines and initiation of anaphylaxis

basophil

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21

cell that is derived from a myeloblast that is the most abundant white blood cell and functions against bacterial infections through pus production, phagocytosis and release of anti-microbial proteins

neutrophils

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22

cell that is derived from myeloblast that functions in toxin release against parasites, allergic reaction response, and tissue damage

eosinophils

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23

two cells derived from a monocyte

macrophage, dendrite

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24

type of white blood cell that are found in the tissues functions in chronic inflammation and adaptive immunity through antigen presentation and phagocytosis

macrophage

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25

type of white blood cell that are found in tissues exposed to external environment and function in antigen presentation and t-cell activation

dendrite

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26

lymphocyte that functions in killing infected tumor cells and initiating innate immunity without prior antigen exposure

natural killer cells

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27

lymphocyte that functions in adaptive immune response

t-lymphocyte

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28

lymphocyte that functions in antibody production for pathogen neutralization

b-lymphocyte

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29

transcription factors that bind to specific genes and promote or inhibit expression of gene are responsible for this cellular phenomenon

specialization

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30

component that functions through receptor binding which activates certain transcriptional factions to intiate a response

steroid hormones

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31

protein that tags unecessary or damaged proteins to be degraded and function in cell signaling regulation

ubiquitin ligase

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32

stem cell that is pluripotent and is derived from early embryos

human embryonic stem cells

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33

stem cell that is multipotent and is used in bone marrow transplant and tissue repair for certain tissue types

adult stem cells

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34

stem cell that is derived from reprogramming adult somatic cells

induced pluripotent stem cells

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