Studied by 7 people
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role of BRCA genes without mutations
repair DNA and prevent uncontrolled cell growth
BRCA gene that is associated with a higher risk of breast cancer and ovarian cancer and is also linked to other cancers including pancreatic and prostate.
BRCA1
BRCA gene that is less severe but increases the risk for breast cancer, ovarian cancer, pancreatic, prostate and male breast cancer
BRCA2
type of stem cell that has the ability to develop into any cell type or complete organism
totipotent
type of stem cell that has the ability to develop into any cell type within an already existing organism excluding extra-embryonic tissue
pluripotent
type of stem cell that can differentiate into any cell types within a specific lineage of tissue
multipotent
type of stem cell that can produce a limited number of cell types within a specific lineage of tissue
oligopotent
type of stem cell that can differentiate into only one specific cell type
unipotent
components of the ectoderm
skin, nervous system
components of the mesoderm
muscles, blood, bones
components of the endoderm
internal organs
three types of stem cells
embryonic, fetal, adult
three types of stem cells that are found in adult bone marrow
hematopoietic, endothelial, mesenchymal
process of blood cell formation that occurs primary in bone marrow
hematopoiesis
stem cell responsible for hematopoiesis
hematopoietic
two cells that emerge from hematopoietic stem cels
myeloid progenitor, lymphoid progenitor
cell that is derived from a myeloid progenitor that functions in blood clots and wound healing
thrombocytes
cell that is derived from a myeloid progenitor that functions in delivering oxygen to tissues and returning carbon dioxide to lungs
erythrocytes
cell that is derived from a myeloid progenitor that functions in immune response with the tissue to elicit a localized immune response
mast cell
cell that is derived from a myeloconblast that functions in response to allergic reactions and inflammation throughout the blood by release histamines and initiation of anaphylaxis
basophil
cell that is derived from a myeloblast that is the most abundant white blood cell and functions against bacterial infections through pus production, phagocytosis and release of anti-microbial proteins
neutrophils
cell that is derived from myeloblast that functions in toxin release against parasites, allergic reaction response, and tissue damage
eosinophils
two cells derived from a monocyte
macrophage, dendrite
type of white blood cell that are found in the tissues functions in chronic inflammation and adaptive immunity through antigen presentation and phagocytosis
macrophage
type of white blood cell that are found in tissues exposed to external environment and function in antigen presentation and t-cell activation
dendrite
lymphocyte that functions in killing infected tumor cells and initiating innate immunity without prior antigen exposure
natural killer cells
lymphocyte that functions in adaptive immune response
t-lymphocyte
lymphocyte that functions in antibody production for pathogen neutralization
b-lymphocyte
transcription factors that bind to specific genes and promote or inhibit expression of gene are responsible for this cellular phenomenon
specialization
component that functions through receptor binding which activates certain transcriptional factions to intiate a response
steroid hormones
protein that tags unecessary or damaged proteins to be degraded and function in cell signaling regulation
ubiquitin ligase
stem cell that is pluripotent and is derived from early embryos
human embryonic stem cells
stem cell that is multipotent and is used in bone marrow transplant and tissue repair for certain tissue types
adult stem cells
stem cell that is derived from reprogramming adult somatic cells
induced pluripotent stem cells
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