SG Diseases MRSA

What are some general characteristics of Staphylococcus aureus?

• normal microbiota of skin and nose of healthy people

What are some minor and serious staph infectious symptoms?

• sometimes causes skin infections- skin barrier is broken/invaded by medical procedure

• serious infections- surgical wound infection, bloodstream infections, pneumonia, UTI

% of folks with S. aureus?

% of folks with MRSA?

• 20-30% of population colonized in nose

• 2% of population colonized with MRSA

What is MRSA and when did it show up?

What is VISA?

What is VRSA?

Methicillin- in 1959 was first semisynthetic penicillin designed against penicillinases

Vancomycin intermediate-resistant S. aureus

Vancomycin resistant S. aureus

What is HA-MRSA and where does it frequently occur (what are some characteristics of it)?

Healthcare-associated Methicillin Resistant S. aureus

persons in hospitals and healthcare facilities

• main reservoirs are infected or colonized patients

• personnel can be reservoirs but are mostly links for transmission between patients

  • main mode of transmission

What is CA-MRSA and some characteristics of it?

• Rise in Community-associated MRSA

  • people who have not been recently hospitalized or had a medical procedure

  • young and healthy

  • prisoners, athletes, school/daycare children, military recruits

  • usually, this MRSA is susceptible to more types of antibiotics

List some treatment regimens for MRSA.

• drain boil/abscess- by healthcare provider

• vancomycin or teicoplanin

  • now strains of MRSA showing resistance to these antibiotics

  • new antibiotics

    • linezolid (Zyvox)

    • daptomycin (Cubicin)