Bio midterm (copy)
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Last updated 1:26 PM on 1/12/23
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8 Terms
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What kind of model is DNA replication?
Semiconservative model
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Step 1 of DNA replication:
Helicase: unwinds DNA at origins of replication. Creates replication forks
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Step 2 of DNA replication.
Initiation proteins separate 2 strands. Forms a replication bubble.
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Step 3 of DNA replication
Primase: puts down RNA primer to begin replication
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Step 4 of DNA replication
DNA Polymerase III: Adds complimentary bases to leading strand. New DNA is made from 5‘ to 3’
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Step 5 of DNA replication
Lagging strand grows in 3’ - 5’ by addition of Okazaki fragments.
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Step 6 of DNA replication
DNA Polymerase I: replaces RNA primer with DNA
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Step 7 of DNA replication
DNA Ligase - seals fragments together. DNA replication is completed.
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