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The brainstem and cerebellum are a part of the brain and therefore are apart of the
Central nervous system
The brainstem is composed of 3 parts (from superior to inferior
Midbrain, pons, medulla oblongata
the inferior portion of the brainstem, the medulla, is
continuous nervous tissue with the spinal cord
what designates where the brain and spinal cord begin
foramen magnum
what is the most inferior and posterior of the brain parts
cerebellum
vertical tract runs through the brainstem
sensory, autonomic, and motor tracts travel through the brain stem, just as in the spinal cord
brainstem acts as a conduit for the continuing tracts, and some tracts originate in
the brain stem region
10 out of 12 pairs of cranial nerves originate on the
brainstem
Longitudinal sections
Basilar, tegmentum, tectum
basilar: anterior located, contains
predominantly motor structures although some sensory
tegmentum: posteriorly located to basilar contains
sensory nuclei/tracts, reticular formation and cranial nerve nuclei, involved in adjusting general level neural activity
tectum: posterior to tegmentum in midbrain, regulates
eye and auditory reflexes and reflexive head movements.
Reticular formation of the tegmentum
complex neural network formation within the tegmentum, including the reticular nuclei, their connections and ascending and descending reticular pathways
reticular formation can be divided into 3 longitudinal zones
lateral zone, Medial zone, midline zone
lateral zone:
integrates sensory and cortical input
medial zone:
regulates vital functions, somatic motor activity and attention
midline zone:
adjusts transmission of pain info, somatic motor activity, and consciousness levels
reticular nuclei
it regulates the passage of ascending/descending information by releasing chemical signals (neurotransmitters)
ventral tegmental area/nucleus (lateral zone)
dopamine (motor control/ coordination, behavior)
pedunculopontine Nucleus (lateral zone):
acetylcholine (arousal, ascending signals to thalamus and cerebrum)
locus ceruleus/ cerulean nucleus (lateral zone):
norepinephrine (enhanced movement percision, increase wakefulness)
medial reticular zone:
epinephrine/ norepinephrine (movement control)
Raphe Nuclei (midline zone):
serotonin (pain inhibition, mood regulation, anxiety reduction, consciousness)
Medulla
control of eye and head movements, coordinates swallowing, and helps regulate cardiovascular, respiratory and other visceral activity
pyramids:
anteriorly, the medulla has tv vertical ridges called pyramids. most corticospinal axons cross the midli in the pyramid decussation
pons
process motor information from the cerebral cortx and forwards it to cerebellum
midbrain
relay station for visual and auditory information, controls body movements
anatomy of cerebellum: cortex
outer cortical region- gray matter consisting of three cortical layers
three cortical layers:
outer layer/ molecular layer: Purkinje cells dendrites
middle layer/Purkinje cell layer: Purkinje cell bodies
inner layer/granular layer: granule cells and golgi cells
cortex 2 inner cortical region
whote matter- deeply seated within the cortex consists of cerebellar nuclei, recieves input from purkinje cells
lobes of the cerebellum (divides cerebellum from rostral to caudal direction)
anterior: most superior lobe, separated from posterior lobe by primary fissure
posterior: most inferior, largest lobe
flocculondular: tucked underneath the posterior lobe, touching the brainstem
three specialized regions of cerebellum coordinate body movements and postural control:
vestibulocerebellum, spinocerebellum, cerebrocerebellum
vestibulocerebellum (flocculonodular lobe):
balance and spatial orientation
spinocerebellum (vermal and paravermal)
vermal hemisphere: processes auditory and vestibular information and posture
Paravermal hemisphere: gross limb movements
cerebrocerebellum (lateral hemispheres)
controls distal, fine and coluntary movements
brainstem disorders
dysphagia, dysarthria, diplopia, dysmetria
dysphagia
difficulty swallowing: affecting pharynx, gag reflex cranial nerve
dysarthria
difficulty in speaking: speech disorder can cause slurred or abnormal articulation; affects the ability to form words
diplopia:
eye movement disorders causing double images: cranial nerves originate on the brainstem and deal with eye movements via ocular muscles
dysmetria
inability to determine distance of movements: affects reaching for objects or stepping: over or underestimating where an object is located
cerebellum disorders:
ataxia, dysarthria, dysmetria
ataxia:
imbalance and loss of coordination of movement: failure of muscle control: can result in stumbling, balance issues , slurred speech, balance issues
c. dysarthria
motor problems with speech: neurological damage that cause speech disorder c
c. dysmetria:
to determine distance of movements: affects reaching for objects c