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Modern genetics began with who?
Gregor Mendel
Mendel documented the inheritance of…
Peas
What are the two theories of inheritance?
Blending theory
Particulate theory
Blending theory:
Offspring are a straight mix
Particulate theory:
Traits are inherited as particles; offspring receive a piece from each parent, some pieces hide others
Mendel work showed the ____________ theory wrong
Blending
Ovists:
Thought an egg was important; male was fertilization agent
Spermists:
Thought the sperm was important; egg was growing agent
Generations of Mendel’s peas:
P→F1→F2
For the F2 plants, he allowed them to ___________
Self-polinate
Alleles:
Different versions of gene at same location on homologous chromosomes
Alleles vary in the sequence of ____________ at the specific _______ of a gene
Nucleotides; locus
Diploid organism inherits….
Two alleles, one from each parent
Dominant alleles have a __________, allowing them to mask other alleles
Functional protiens
Recessive alleles have a __________, allowing them to be masked by other alleles
Malfunctioning protien
Homozygous:
Same alleles (PP, pp)
Heterozygous:
Different alleles (Pp)
Two organisms can have the same ___________ but have different _________
Phenotype; genotype
Test cross:
Breed the dominant phenotype with a homozygous recessive to determine identify of unknown allele
Mendel 1st law of heredity:
Law of segregation
Law of segregation:
During meiosis, alleles (homologous chromosomes) segregate
Which stage of meiosis creates the law of segregation?
Metaphase 1
Monohybrid cross:
Organism follows the inheritance of a single character (flower color OR seed color)
Dihybrid cross:
Organism follows inheritance of two different characters (seed color AND seed shape)
Mendel 2nd law of heredity:
Law of independent assortment
Law of independent assortment:
Different loci (genes) separate into gametes independently
Which stage of meiosis creates the law of independent assortment?
Metaphase 1
What is the exception for the law of independent assortment?
If genes are on the same chromosome and close together (linked)
The chromosomal basis of Mendels laws trace the genetic events through…
Meiosis, gamete formation, fertilization to offspring
Law of segregation=________ cross
Monohybrid
Law of independent assortment=________ cross
Dihybrid
Why are pea plants good for genetic research?
Many varieties, distinct features, simple genetically
Alleles separate…
Randomly
Multiplication rule:
Determines the probability of two or more independent events
Addition rule:
To figure out the probability of an offspring being heterozygous
Addition rule: events are…
Mutually exclusive
You can apply the multiplicative rule to the dihybrid __:__:__:__ cross
9:3:3:1
Chi-squared is a form of analysis used to compare the __________ results with the ___________ results to determine whether the results are ____________________
Observed (actual); expected; statistically signifigant