Function Prediction using Model Organisms

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Last updated 4:21 PM on 1/7/26
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4 Terms

1
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Why compare human genes to yeast homologues

Infer function by conservation

2
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What does high sequence identity suggest

Similar biological function

3
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How were Msh2 cancer mutations studied

Expressed in yeast

4
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What defects were revealed in Msh2 mutants

Protein instability and reduced repair activity

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