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Hydrostatic skeleton
Fluid filled cavity surrounded by muscles. The muscles exert force against the fluid to facilitate movement. (Earthworms)
Exoskeleton
External, rigid skeleton composed of chitin. Provides attachment and serves as the site of muscle attachment. Growth, however, is restricted. (arthropods such as crustaceans)
Endoskeleton
Composed of rigid internal elements the provide structural support and muscle attachment points. Primarily composed of bone and cartilage or calcite
Cartilage
A specialized connective tissue designed to withstand compression and tension; it is tough yet flexible and found in many joints
Chondroblasts
Cartilage consists of ____________ which secret extracellular matrix and becomes trapped within lacunae, maturing into chondrocytes.
Glycoproteins and collagen fibers
Cartilage matrix is composed of…
avascular
Cartilage is ___________, meaning it lacks blood vessels and because of this, it heals slowly.
Bone
A specialized connective tissue that is strong but inflexible.
collagen fibers and polysaccharides
Bone consists of organic components such as __________ and ___________ for flexibility.
inorganic hydroxyapatite
Bone consists of ______________________ for hardness.
Osteoblasts
____________ secrete an enzyme that promotes hydroxyapatite formation, giving bone its rigidity.
osteocytes
Some osteoblasts become trapped in the matrix, transforming into ______________, which reside in lacunae and connect via tiny canals called canaliculi for intercellular communication.
Intramembranous ossification
Process by which flat bones like the skull develop
Endochondral ossification
Process by which long bones like the vertebrate, ribs, and limbs develop
epiphyses
Growth occurs at the ______________ (widened ends of bones) in growth plates made of cartilage.
bone lengthening
Young cartilage cells undergo mitosis, thicken, age, and die, contributing to ________________.
calcification
Young cartilage cells undergo mitosis, thicken, age, and die, contributing to bone lengthening.
Simultaneously, _______________ occurs from the shaft side, replacing cartilage with bone.
late adolescence
Growth in length stops in _______________, but width growth continues throughout life.
Osteoblasts
Involved in bone formation
mechanical stress and hormones
Bone remodeling is stimulated by ____________and_______________.
produce more bone matrix
Increased mechanical stress (e.g., weightlifting) signals osteoblasts to __________________________, strengthening the bone.
bone deposition
Osteoporosis occurs when bone resorption outpaces _______________, leading to fragile bones. Treatments include a high-calcium diet, vitamin D, and weight-bearing exercise to stimulate bone growth.
contract
Muscles ____________ to generate movement at joints
Origin
The fixed attachment point of a muscle.
Insertion
Movable attachment point
Antagonistic muscles
One muscle produces a movement that is reversed by another (e.g., quadriceps extend the leg while hamstrings flex it).
Ball-and-socket
Joints that allow a wide range of motion (hip, shoulder)
hinge joints
Joints that permit movement in one direction (knee, elbow)
Gliding joints
Joint that allows sliding motions (vertebrae, wrist)
Combination joints
allow rotation and side to side movement (jaw)
long multinucleated muscle fibers
Skeletal muscle consists of bundles of _________________________.
thick (myosin) and thin (actin) filaments
Each muscle fiber contains myofibrils, composed of
sarcomere
The structural unit of contraction is the ___________, spanning from Z-line to Z-line.
A bands
_________ (dark regions) contain stacked thick filaments.
I bands
___________ (light regions) contain only thin filaments.
H zone
________ (within A band) has only thick filaments
slide past each other
During contraction: Actin and myosin filaments ________________, shortening the sarcomere
Myosin heads
____________ bind to actin, forming cross-bridges.
Power stroke
Myosin pulls actin toward the sarcomere’s center
tropomyosin
At rest, ___________ blocks actin-binding sites
troponin
Calcium ions (Ca²⁺) bind to ___________, shifting tropomyosin to expose actin-binding sites.
sarcoplasmic reticulum
Ca²⁺ is released from the __________________ when stimulated by a motor neuron at the neuromuscular junction.
Slow-twitch fibers
Rely on aerobic respiration.
High capillary density, mitochondria, and myoglobin (appear dark).
Fatigue-resistant, ideal for endurance activities (e.g., marathon running).
Fast twitch fibers
Generate rapid power, fatigue quickly.
Some respire anaerobically, relying on glycogen stores.
Fewer capillaries, mitochondria, and myoglobin (appear white).
Suited for short bursts of activity (e.g., sprinting).
Osteoclasts
dissolves bone by releasing Ca++ (immune cells derivatives)
lacunae
These are small spaces connected by canaliculi containing osteocytes in the Haversian system