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Late Effects
Appear months or years after exposure, principle late effects are malignancy and genetic effects; radiation protection guidelines are based on observed or suspected late effects
What dose response relationship does late effects follow?
Linear non-threshold
What is the tissue response of late effects?
Stochastic
Epidemiologic Studies
Studies of large numbers of people exposed to toxic substances
What are some late effect limitations?
Natural incidences, control group accuracy, statistical significance, isolation of other contributing factors and dosimetry estimates