anti hep B/C and local antivirals

the prototype anti hep B medication is

adefovir

adefovir works to

terminate the DNA chain of anti hep B

adefovir is used specifically for

chronic HBV with an increase in alanine and asperate aminotrans

adefovir is known to cause

asthenia (profound weakness)

the second anti hep B med is

tenofivr alafenamide

the anti hep B med tenofivr is a

new medication that is great for patiets with liver disease

aside from profound weakness the two major side effect of adefovir is

• fatal hepatomegally with stenosis

• lactic acidosis

will look like a shock patient

for the anti hep B med tenofivr it is crucial to monitor creatine clearance becuase if

CrCl is less than 15 then the patient must be on dialysis

it is crucial that patients taking tenofivr are not also taking

nephrotoxic drugs

the final and third anti hep B med is

entecavir

entecavir is specifically for

chronic HBV with increased LFT

all people taking any anti hep B meds must also use

condoms

when taking an anti hep B med, a patient should immediately notify the provider if they expereice any signs of

jaundice

all anti hep B meds can cause a risk of

• hepatotoxicity

• lactic acidosis

• increase in hepatomegally

it is crucial that all anti hep B meds are not

stopped abruptly

the prototype anti hep C med is

epculsa

epculsa is a combination between

sofo and velp

the individual portion of epculsa (sofo) works by

inhibiting enzymes for replication

the individual portion of epculsa (velp) works by

inhibiting protein for replication

the anti hep C med epculsa can only be taken if the patient is

• 6 years old

• weighing 17 kg

  • for all genotypes

the second combination of drugs for hep c is

gleca and pibrent

the anti hep C meds gleca and pibrent is can only be taken if the patient is

• 12 years old and 45 kg

• for all genotypes

the final anti hep C medication combo is

Elbas and Grazo

the anti hep C med elbas and grazo are used for

• genotypes 1 and 4

• adults only

all anti hep C med can cause an

HBV reactivation with HIV drugs

if taking anti hep C drugs you cannot also take

• protease inhibitors

• st. john wort

all hep c drugs can cause a patient to expereice

Gi upset

when prescribing hep C drugs it is crucial to ask the patient about any

coinfections

acyclovir (zov) is used to treat

recurrent herpes labialis (cold sores)

docosanol ( abrev) is used to treat

oral and facial herpes simplex

ganciclovir (zirgan) is used to treat

opthomalic gel herpetic kertinitits

imiquimod is used to treat

genital warts

penciclovir is used to treat

cold sores on the face and lips