COCAINE

DRUG TEST 2

neurotransmitter

dopamine

norepinephrine

earliest use

incas (5000 BCE)

disocvery

isolated Niemann (1860)

acute effects

increased energy

euphoria

local anesthesia

chronic effects

paranoia

hallucinations

cardiac toxicity

high dependce & tolerance

cause depression after ‘crash’

comes from

coca leaves 2%

crack

cocaine + baking soda

cocaethylene (dangerous)

cocaine + alcohol

Freued praised drug

suggest use for treating morphine addiction

who mixes coke & alc (wine)

angelo mariani (1863) (vin mariana)

medical use of cocaine

eye surgery

neurotransmitter causing euphoria

dopamine

pupils response

dialated

1914 law restrict cocaine & opiates

harrison act

cocaine inhibits for catecholamines

reuptake

coca cola’s father

Pemberton

adminstration through snorting

insufflation

apart of larger drug class

major stimulant

local medicinal effect

Anesthesia