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20-50
multiple sclerosis has a gradual onset, and commonly occurs at age _____
permanent loss of function
as ongoing inflammation from multiple sclerosis occurs, there is:
- blurred or double vision, color distortions, blindness in one eye
- weakness in extremities; problems with coordination, balance, walking and standing
- paresthesias in the lower extremities and hands
- lhermitte’s sign
- fatigue
- pain, aches
- dysarthria
- tremors
- dizziness
- hearing loss
- nystagmus
- bowel and bladder dysfunction
- sexual dysfunction
- ataxia
- cognitive function changes
- remission during pregnancy
*has a ‘spotty’ distribution in the CNS: manifestations vary according to the area involved
clinical manifestations of multiple sclerosis:
lhermitte's sign
transient electric shock radiating down the spine or into the limbs with flexion of the neck - AKA: barber chair sign
progressive-relapsing multiple sclerosis
pattern of multiple sclerosis: steady decline in function since onset with superimposed attacks
secondary progressive multiple sclerosis
pattern of multiple sclerosis: initial relapsing-remitting multiple sclerosis that suddenly begins to have decline without periods of remission
primary progressive multiple sclerosis
pattern of multiple sclerosis: steady increase in disability without attacks
relapsing-remitting multiple sclerosis
pattern of multiple sclerosis: unpredictable attacks which may or may not leave permanent deficits followed by periods of remission - most common
sclerotic plaques in the brain - inflammation - atrophy of the brain - tissue destruction
an MRI of a patient with multiple sclerosis may show:
evoked potential response
tests for the speed of transmission through nerves - if the speed is delayed, then MS is considered
expanded disability status scale (EDSS)
questionnaire that focuses on symptoms, exacerbations, remissions, and impact on ADLs - a good tool to use to diagnose and to follow the effectiveness of treatment
baclofen
a skeletal muscle relaxant used for patients with muscle spasms
intrathecal baclofen
a catheter is inserted into the spinal column and a medication is administered through a pump to help prevent muscle spasms
dorsal column electrical stimulation
a probe is inserted into the spinal column and electrical impulses are delivered to speed the rate of impulses through the nerve
water exercises: water exercises do not put any stress or strain on the affected limbs while allowing the patient to move freely in the water
what type of exercise therapy would be beneficial for a patient with multiple sclerosis?
apathy - inattentiveness - depression
often are signs of cognitive dysfunction associated with MS
prevent injury and infection
what is the main focus for a patient with multiple sclerosis?