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17 Terms

1
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Apoptosis

cytochrome c, AFAB1, Procaspase 9

2
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Signaling

RTK, CTK dimer phosp

3
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Protein Cleavage

FasL, procaspase 3, CAD —> nucleus

4
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expression

c-myc, APC, beta cateninm

5
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more apc

less c myc

6
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more b catenin

more c myc

7
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Ras (GDP)

sos

8
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RAS gtp

gtpase (gap)

9
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NF1

ras on

10
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chromosomes for follicular lymphomas

14, 18

11
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kinase cascade

RTK, RAS, RAF, MEK, ERK, c-myc

12
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nf1

tumor supressor

13
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rtk ras

protooncogenes

14
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EMT

twist, snail, sip1

15
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emt

epitheleal —> mesenchymal

16
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extrasavation

CAF, CXCL, TAM, VEGF (leaving)

17
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