Cell Wall Inhibitors and Other beta lactam antibiotics
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5 Terms
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Penicillins
MoA: Binds PBPs (penicillin-binding proteins); inhibits transpeptidase
Adverse Effects:
Hypersensitivity (rashes to angioedema and anaphylaxis)
diarrhea,
nephritis,
neurotoxicity,
hematologic toxicities.
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Cephalosporins
Moa: Binds PBPs; inhibits cell wall synthesis
AE:
Allergic reactions,
diarrhea,
nephrotoxicity (rare).
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Carbapenems
MoA: Binds PBPs; inhibits cell wall synthesis
AE: Seizures (imipenem),
GI upset,
pseudomembranous colitis.
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Monobactams
relatively non-toxic
AE: Phlebitis,
rash,
elevated liver enzymes.
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Other beta lactam antibiotics
Carbapenems and monobactams
Note 
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