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Transformation experiment gel electrophoresis (Figure 1)
B — E. coli in lane B have been successfully transformed and contain additional genetic information.
Prokaryote vs eukaryote chromosome structure
D — Prokaryotes have a single circular chromosome; eukaryotes have multiple linear chromosomes.
Lynch syndrome inheritance
B — The individual has an increased risk of developing colon cancer.
Restriction enzyme gel electrophoresis comparison
D — Species A has more short fragments of DNA than species B does.
Semiconservative DNA replication
D — Each newly synthesized strand remains associated with its template strand.
Cycloheximide translation inhibition
C — CPM increases, plateaus when inhibitor is added, then increases again when inhibitor is removed.
Retrovirus infection mechanism
C — Reverse transcriptase produces DNA from viral RNA that integrates into the host genome.
UV radiation DNA damage
D — UV photons cause dimers to form, distorting DNA and causing replication errors.
Evidence tryptophan is a corepressor
D — When trpR is mutated, the operon is transcribed regardless of tryptophan levels.
Alternative splicing long-term effect
A — The cell will die because it cannot metabolize the substrate without enzyme A.
Enzyme 1 at replication fork
B — Enzyme 1 is DNA primase that synthesizes RNA primers on the lagging strand.
Regulation of TYR, TRP2, TRP1 genes
B — The genes may be on different chromosomes but are activated by the same transcription factor.
Why keratinocytes do not produce melanin
A — Keratinocytes do not express the genes encoding melanin-synthesizing enzymes.
miRNA inhibition of translation
C — Altering the miRNA binding site allows translation even when miRNA is present.
rRNA processing
C — Sections of pre-rRNA are removed and mature rRNA combines with proteins to form ribosomes.
Huntington’s disease inheritance
B — She inherited an allele with more than 40 CAG repeats from her father.
Replication bubble strand synthesis
C — Strand I is synthesized continuously; strand III is synthesized in segments.
Gene regulation by DNA sequences
B — Some DNA sequences interact with regulatory proteins to control transcription.
Cystic fibrosis mutation type
C — Deletion mutation causes a frameshift.
DNA base pairing chemistry
C — Hydrogen bonds join a purine to a pyrimidine.