Excipients (help me)

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71 Terms

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Acidifying Agent

Provides acidic medium for product stability

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Acidifying agent

Citric acid

Acetic acid

Hydrochloric acid

Nitric acid

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Alkalinizing agent

Provides alkaline medium for product stability

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Alkalinizing agent

Ammonium carbonate

Sodium bicarbonate

Sodium borate

Sodium carbonate

Sodium hydroxide

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Adsorbent

Holding other molecules onto its suface by physical or chemical (chemisorption) means

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Adsorbent

Powdered Cellulose

Activated Charcoal

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Aerosol Propellant

Develop pressure within an aerosol container and expelling the product when the valve is opened.

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Aerosol Propellant

CO2

Dichlorodifluoromethane

Dichlorotetrafluoromethane

Trichloromonofluoromethane

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Air Displacement

To displace air in a hermitically sealed container to enhance product stability

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Air Displacement

Nitrogen

CO2

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Antifungal Preservative

Liquid & Semi-solid prep; prevent growth of fungi

Paraben; enhanced use in combination

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Antifungal Preservative

Butylparaben

Ethylparaben

Methylparaben

Benzoic Acid

Propylparaben

Sodium Benzoate

Sodium Propionate

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Antimicrobial Preservative

Prevents microbial growth

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Antimicrobial Preservative

Benzalkonium chloride

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Buffers or buffering agent

Potassium metaphosphate

Potassium phosphate, monobasic

Sodium acetate

Sodium citrate, anhydrous and dihydrous

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Buffers or buffering agent

Resists change in pH upon dilution or addition of acid or alkali

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Chealting Agent

Forms a stable water-soluble complexes with metals; stabilizer to complex heavy metals that promote instability

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Chealting Agent

Editic Acid

Edetate Disodium

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Colorant

Imparts color to liquid and solid preparations, in order to enhance appeal

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Colorant

FD&C (usually colors red, yellow, and blue)

D&C (usually colors green, orange, red)

Ferric oxide, red

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Clarifying agent

Bentonite

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Clarifying agent

Used as a filtering aid for its adsorbent qualities

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Emulsifying Agent

Promote dispersion of particles of liquid in a vehicle.

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Emulsifying Agent

Acacia

Cetomacrogol

Cetyl Acohol

Glyceryl Monostearate

Sorbitan Monooleate

Polyoxyelthylene 50 stearate

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Encapsulating Agent

Form thin shells to enclose a drug for ease of admin

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Encapsulating Agent

Gelatin

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Flavorant

Imparts a pleasant flavor and often odor

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Flavorant

Anise oil

Cocoa

Menthol

Peppermint oil

Vannilin

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Humectant

Prevent drying of prep; ointments & cream

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Humectant

Glycerin

Propylene Glycol

Sorbitol

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Levigating agent

Liquid used as an intervening agent to reduce the particle size of a powder by grinding, usually in a mortar

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Levigating agent

Mineral oil

Glycerin

Propylene glycol

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Ointment base

Semisolid vehicle for medicated ointments

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Ointment base

Lanolin

Petrolatum

Polyethylene glycol ointment

White ointment

Yellow ointment

Rose water ointment

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Plasticizer

To make film more pliable, enhance spread of coat over tablets, beads & granules

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Plasticizer

Diethyl Phthalate

Glycerin

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Solvent

Dissolves another substance in preparation of a solution

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Solvent

Alcohol

Glycerin

Mineral oil

Purified water

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Stiffening agent

Increases thickness or hardness of a preparation, usually an ointment

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Stiffening agent

Cetyl alcohol

Paraffin

White wax

Yellow wax

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Suppository base

Vehicle for suppositories

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Suppository base

Cocoa butter

Polyethylene glycols (mixtures)

PEG 3350

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Surface active ingredient or surfactant

Substances that absorb to surfaces or interfaces to reduce surface or interfacial tension

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Surface active ingredient or surfactant

Benzalkonium chloride

Polysorbate 80

Sodium lauryl sulfate

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Sweetening agent

Imparts sweetness to a preparation

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Sweetening agent

Aspartame

Dextrose

Glycerin

Saccharin sodium

Sorbitol

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Stabilizer

Prevents deterioration or decomposition of preparations, such as antioxidants and chelating agents

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Stabilizer

Ascorbic acid

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Anti-adherent

Prevents tablet ingredients from sticking to punches and dies during production

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Anti-adherent

Magnesium Stearate

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Binder

Cause adhesion of powdered drugs and pharmaceutical substances

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Binder

Acacia

Alginic acid

Carboxymetylcellulose sodium

Gelatin

Liquid glucose

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Diluent

Creates desired bulk, flow properties, and compression characteristics of tablets and capsule

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Diluent

Kaolin

Lactose

Mannitol

Starch

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Coating agent

Coats tablets to protect against decomposition by oxygen or humidity, to mask taste and ordorr, to provide a desired release pattern, and for aesthetic purposes

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Sugar Coating

Liquid Glucose

Sucrose

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Film Coating

Hydroxyethyl cellulose

Hydroxypropyl Cellulose

Hydroxypropyl Methylcellulose

Methylcellulose (Methocel)

Ethylcellulose(Ethocel)

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Enteric Coating

Cellulose Acetate Phhalate

Shellac

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Direct-Compression Excipient

Dibasic calcium Phosphate

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Disintegrant

Promotes disruption of the mass into smaller particles more readily dispersed or dissolved

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Disintegrant

Alginic acid

Sodium alginate

Sodium starch glycolate

Starch

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Glidant

Improves flow properties of the powder mixture

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Glidant

Colloidal silica

Cornstarch

Talc

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Lubricant

Reduces friction during tablet compression

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Lubricant

Calcium stearate

Magnesium stearate

Mineral oil

Stearic acid

Zinc stearate

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Opaquant

Titanium Dioxide

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Opaquant

Render a coating opaque; may be used alone or with a colorant

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Polishing agent

Carnauba wax

White wax

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Polishing agent

Imparts an attractive sheen to coated tablets

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