Principles of Genetics: DNA Repair

This set of flashcards covers key vocabulary related to DNA damage and repair mechanisms discussed in the Principles of Genetics lecture.

DNA Damage

Can be caused by exposure to high energy light rays, mutagens, or replication errors.

Direct Reversal

Repairs DNA damage by reverting bases to their original state depending on specific damage.

Base Excision Repair

A repair process that removes the damaged base (1bp).

Nucleotide Excision Repair

A repair mechanism that removes a segment of DNA surrounding a damaged base. (10 bp).

Mismatch Repair

Corrects errors that occur during DNA replication when incorrect bases are added.

DNA Ligase

An enzyme that facilitates the joining of DNA strands together by forming a bond between them.

Glycosylase

An enzyme that removes damaged or mismatched bases from DNA.

Error-prone repair

Repair systems that are last resorts and are prone to cause mistakes in DNA.

MutS, MutL, and MutH

Proteins involved in the mismatch repair process in E. coli.