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what are the essential functions of the skin?
temperature regulation, barrier protection, secretion and absorption, vitamin d synthesis, immunological defense, clinical indicator
how does the skin control heat loss and retention?
through vasodilation, vasoconstriction, and perspiration
how is the skin a immunological defense?
it houses langerhans cells that detect and respond to foreign antigens
how does the skin help vitamin d synthesis?
it produces vitamin d when it's exposed to ultraviolet radiation
what is a macule?
defined, flat area of altered pigmentation
what is a papule?
raised, well defined lesion measuring less than 0.5 cm
what is a plaque?
raised, flat topped lesion greater than 2 cm
what is a scar?
permanent replacement of normal skin with fibrous connective tissue
what is a ulcer?
loss of both epidermal and dermal tissue extending into deeper layers
what is a vesicle?
small fluid filled blister less than 0.5 cm in diameter
what is a bullae?
large vesicles greater than 0.5 cm appearing as thin skinned, fluid filled bubbles
what is a urticaria?
hives. pinpoint, erythematous, intensely itchy wheals
what is a wheal?
confluent region of urticaria forming erythematous, raised, itchy lesions
what are the 5 key characteristics when assessing the skin?
color, texture, turgor, moisture, and tenderness
what are the disorders of skin pigmentation?
albinism, vitiligo, melasma, lentigos
what is the pathophysiology of albinism?
hereditary. due to genetic mutations that result in defective melanocytes. causes lack of pigmentation
what is pathophysiology of vitiligo? is it acquired or genetic? what is the etiology?
acquired. autoimmune condition where the immune system attacks melanocytes. etiology unclear. leads to discolored skin patches
what is the pathophysiology of melasma?
hyperpigmentation disorder. due to hormone fluctuations usually in pregnancy. appearance of dark macules on the face. more common in brown skinned women
what are lentigos?
benign age spots. increased number of melanocytes. usually caused by increased sun exposure
what are the disorders of skin texture?
xerosis and pruritis
what is the pathophysiology of xerosis?
abnormally dry skin. caused by decreased sebum production, impaired barrier function, and reduced water content in epidermis. more easily bruises. increased infection risk
what is the pathophysiology of pruritis?
itching. symptom and not a diagnosis. can have multiple etiologies