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SIGECAPS of Depression
Sleep disturbances
Interests are ↓
Guilt
Energy is ↓
Concentration is ↓
Appetite is ↓
Psychomotor Agitation
Suicidal thoughts
5 or more x2 weeks = MDE
euphoria, increased energy, increased talking, rapid thoughts, no sleep, don't feel tired
manic episode→lasts at least 7 days
hypomanic at least 4 days
>1 MDE + NO mania/hypomania hx
MDD
first line tx for MDD
SSRI/SNRI
contraindicated in seizure disorders/anorexia
bupropion (wellbutrin)
mania vs. hypomania
Hypomania = 4 days, no impairment of social/work functioning, no psychotic features
Mania = 7 days, impairment, might have psychotic features - needs hospitalization
DIGFAST for bipolar disorder
Distractibility
Indiscretion
Grandiosity
Flight of ideas
Activity increase
Sleep deficit
Talking increase
DIGFAST for hypomania (idk why its different)
Distractibility
Insomnia
Grandiosity
Flight of ideas
Activty increase
Pressured Speech
Thoughtlessness
abnormally elevated or irritable mood lasting 1 week, 3/7 DIGFAST
bipolar 1
>1 MDE + >1 hypomanic episode, no manic episodes
bipolar II
gold standard for bipolar
lithium
medication induced depressive disorder
accutane
narcolepsy 1st line tx
modafinil
cluster A personality disorders
paranoid, schizoid, schizotypal
odd, withdrawn, sus, eccentric
emotionally cold, restricted affect, avoids close relationships, little sexual interest, social isolation
schizoid personality disorder
odd, eccentric/peculiar behavior or appearance of speech, lack of close friends, weird behaviors
schizotypal
long term pattern of unstable emotions, behaviors, beliefs, F>M, unstable interpersonal relationships, fear of abandonment, emptiness, impulsive
borderline personality disorder
I DESPAIRR
5/9 = borderline personality disorder:
Identity disturbance
Disordered affect
Emptiness
Suicidality
Paranoia
Abandonment fear
Impulsivity
Rage
Unstable relationships
cluster B disorders
antisocial, borderline, histrionic, narcissistic
dramatic, attention seeking, impulsive, erratic
sense of self-importance, extreme preoccupation with themselves, lack of empathy
narcissistic personality disorder
provocative for attention, shifting emotional states that seems fake, change opinions based on what others think, seductive behavior, influenced by others
histrionic personality disorder
cannot and will not conform to societal norms, commit unlawful acts, lack of remorse, harms animals
antisocial personality disorder → behavior before age 15
cluster C personality disorders
avoidant, dependent, obsessive-compulsive
low self esteem, worries about being criticized, feels inadequate, avoids jobs with interpersonal contact, fear of embarrassment
avoidant personality disorder
preoccupied with rules, orderliness, and control, perfectionist, controlling, workaholic, obsessions/compulsions are rare
OCPD
has others assume responsibility for major areas of their lives, discomfort when alone, indecisive
dependent personality disorder→avoid benzos
intrusive symptoms, avoidance symptoms, negative mood, arousal/reactive symptoms
PTSD →SSRIs
PTSD symptoms that occur for less than one month
acute stress disorder
recurrent and persistent thoughts, urges, or images along with repetitive behaviors or mental acts/rituals
OCD
MC hallucination
auditory
depakote causes _________ tox
liver
lithium causes ____________ tox
renal
renal impairment + risperidone =?
decrease dose by 50%
drugs that prolong QT
zofran
geodon
clarithromycin
hallucinations, delusions, disorganized speech, disorganized behavior, negative symptoms
2/5 for 6 months = schizophrenia
schizoaffective disorder
Psychotic disorder featuring symptoms of both schizophrenia and major mood disorder.
russell's sign
calluses on hands that are physical signs of bulimia
1st line pharm tx for bulimia
prozac
FDA approved for tx of BED
vyvanse
when do alcohol withdrawal seizures occur?
within first 6-48 hrs of last drink
most severe form of withdrawal syndrome
delirium tremens
z-bars
xanax
angel dust
PCP
increased energy, feeling of pleasure, enhanced tactile experiences
MDMA (ectasty, molly) intoxication
MDMA cause of death
hyperthermia and dehydration
benzo reversal agent
flumazenil
tachycardia, hyperthermia, HTN, seizures, diaphoresis, mydriasis
cocaine intoxication
FGA vs. SGA
first gen: more extrapyramidal sx d/t D2 blockade
Second gen: more metabolic side effects
personality disorder with greatest suicide risk
borderline
MC population for suicide
M >65 y/o
can't recall from a period of time
localized amnesia →MC
remember some but not all events during a period of time
selective amnesia
unreality, detachment, watching yourself outside your body, no sense of control over actions
depersonalization
foggy, dream like, behind a veil, unreality or detachment with respect to surroundings
derealization
2 or more distinct personalities whose identities differ
DID
abdominal/general pain, diarrhea/constipation, heartburn, preoccupied with health
somatic symptoms disorder →high levels of anxiety and worry about body
extreme out of proportion anxiety about health, no somatic symptoms
illness anxiety disorder →doc hopping, repeated testing
falsify sx and illness to obtain external rewards (money, no work, avoid duties)
malingering
tourette's treatment
tetrabenazine
aggression to people and animals, destruction of property, deceitful/theft, no remorse, violation of rules/law, onset before 18 y/o
conduct disorder →inc. risk of antisocial PD
1st line for MDD in peds
fluoxetine
kids with depression often present as ___________ rather than depressed
irritable
arousal from causing psych/physical suffering of another
sadism