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What headache type/ cause is associated with seizures?
encephalitis
What headache type/ cause is not associated with seizures (unlike its counterpart)?
meningitis
What type of headache?
unilateral, pulsating, aggravated by exercise, moderate to severe intensity, n/v, photophobia and/or phonophobia
migraine
what type of headache?
bilateral, non-pulsating, not aggravated by exercise, mild to moderate intensity, no n/v, no more than one of phonophobia or photophobia
tension headache
What headache type:
eye pain and lacrimation; also see trigeminal shit getting fucked or the cavernous sinus being inflammed
cluster headache
What do we suspect with: older female, pain with chewing (claudication), boring in quality?
giant cell (temporal) arteritis
What do we suspect if we see alpha synuclein and capgras?
lewy body dementia
What do we suspect if we see autonomic insufficiency (urinary incontinence or retention), orthostasis, and stridor?
multiple system atrophy (MSA)
What do we suspect with hemidystonia, alien limb, cortical deficits/atrophy, and absence of a resting tremor?
corticobasal degeneration
What do we suspect if we see GBA1 mutation or LRRK2
parkinson’s or lewy body dementia
what do we suspect if we see doll’s eyes, tauopathy, angry or puzzled look, growling speech, and dysphagia?
progressive supranuclear palsy
What do we suspect if we see Ashkenazi jews or pts of north African Berber descent?
parkinson’s (want to get genetic testing)
What if we see a cape-like distribution of pain and temperature disruption in upper extremities?
syringomyelia/ syrinx formation
what if we have a CSF filled sac only
cranial-meningocele
What is we have a defect and see a sac that has the cerebral cortex, cerebellum, and parts of the brainstem in it?
encephalocele
what is it when the neurons do not migrate to the surface; the neurons get stuck in the subcortical white matter
subcortical band heterotopia
what is it if we see displacement of the tonsils only; associated with syringomyelia
chiari I
What is it if we see the vermis, brainstem, and 4th ventricle herniating; associated with myelomeningocele and myeloschisis
chiari II
what is it if the neuron did not migrate superficially from the edges of the neuronal tube?
periventricular nodular heterotopia
what is it if we see an increase of alpha-fetoprotein and polyhydramnios
anencephaly
What is it if we see cerebellar vermis agenesis, cystic 4th ventricle, and enlarged posterior fossa?
Dandy walker
What aphasia do we see hesitant speech/non-fluent aphasia, repetition of words is intact, and they have good comprehension?
transcortical motor aphasia
What aphasia do we see poor comprehension, intact repetition, and reading and writing is impaired?
transcortical sensory aphasia
what aphasia do we see difficulty with repetition of words?
conduction aphasia
what stroke do we see contralateral weakness of face> arm> leg and they look at their stroke?
middle cerebral artery stroke
What seizure/epilepsy do we see a mutation in SCN1A gene?
Dravet syndrome
What seizure/epilepsy do we see a mutation in GNAQ gene, we also see somatic mosaicism?
Sturge-weber syndrome
What seizure/epilepsy do we see a mutation in KCNJ10 gene and too much K+?
East syndrome
What seizure/epilepsy do we see a mutation in EAAT2gene?
DEE41 syndrome
What seizure/epilepsy do we see a mutation in TSC1 or TSC2 gene, ashleaf spots, and shagreen patch?
tuberous sclerosis
With the infant exam, what is a bean-shaped foot called?
metatarsus adductus
With the infant exam, what is a club foot?
congenital talipes equinovarus
what is the root word if we see a sac/defect covered in skin?
-cele
what is the root word if we see a sac/defect not covered in skin?
-schisis
What is the pneumonic for the cyanosis that is not normal in infants?
5 T’s
What is the normal temp for an infant?
36-38C (96.8-100.3F)
What is the normal HR for an infant?
100-160 BPM
What is the normal RR for an infant?
30-60 breaths per minute
What disease do we see presenilin 1 and 2 and possible hydocephalus ex vacuo
Alzheimers (also see plaques and tangles, cortical atrophy, and APP E4)
What disease do we see knife-edge, thin, wafer like gyri, neuronal loss, and intense gliosis?
Pick disease
What disease do we see NCA gene and alpha synuclein
parkinsons
What disease do we see severe atrophy of the basal ganglia and loss of striatal neurons?
Huntington (also see CAG repeats and choreiform)
What disease do we see the “onion bulb” and thickening of the peripheral neurons that can be clinically palpated?
Charcot-Maria tooth disease
What disease do we see supraoxide dismutase, everything goes up with the UMN lesion, and we see upper and lower neuron loss?
ALS
What disease is associated with iron deficiency anemia?
restless leg syndrome
What stage of sleep do we see delta waves?
N3
Hypnogogic versus hypnopompic
Hypnogogic: awake to sleep
hypnopompic: sleep to awake
What eye disease do we see abnormal optic nerve embryogenesis?
DeMorsier’s syndrome
What eye disease do we see red and green color defects?
congenital color blindness
What eye disease do we see blue and yellow color defects?
acquired macular disease/degeneration
What eye disease do we see a Christmas tree cataract?
myotonic dystrophy
What eye disease do we see people also develop MS?
optic neuritis
What eye disease do we see with a comatose pt that has an uncal herniation and a poorly reactive pupil?
Hutchinson’s pupil
What is the sign that we look to see if the herpes zoster is in the eye by looking at the nose?
hutchinson’s sign
What eye disease would we see a pt that was in a dark room and developed sudden eye pain?
acute glaucoma
At what time frame would we see eosinophilic cytoplasm and pyknotic nuclei?
0.5-1 day
At what time frame would we see necrosis and neutrophils?
1-3 days
At what time frame would we see macrophages?
3-5 days
At what time frame would we see reactive gliosis (astrocytes) and vascular proliferation?
1-2 weeks
At what time frame would we see a glial scar?
>2 weeks
When do we see contralateral arm and face weakness?
an occlusion of the MCA
When do we see an “embolic shower” with clots on both sides of the brain?
cardiogenic embolic stroke
What cerebrovascular disease do we see reperfusion with mass effect?
parenchymal hemorrhage
What cerebrovascular disease do we see reperfusion without mass effect?
hemorrhagic infarction
What disease do we see long standing hypertension, degeneration of the tunica media, and blood in the basal ganglia?
Charcot-Bouchard aneurysm
When do we see a starburst pattern in the brain?
subarachnoid hemorrhage (most common at ACOM)
What is it when we see tearing of the bridging veins?
subdural hematoma
What is it when the middle meningeal artery is bleeding?
epidural hematoma
What cerebrovascular disease do we see an issue at the common carotid bifurcation?
amarousis fugax (see the shade over eyes)
What is it when we see a “lake-like’ appearance on the MRI?
lacunar stroke
What seizure/disease/epilepsy do we see hypsarrhythmia on the EEG? How do we treat it?
infantile spasm (West syndrome)
treat with ACTH and vigabatrin
What seizure/disease/epilepsy do we see sharp centrotemporal waves on the EEG? How do we treat it?
Rolandic epilepsy
treatment not required
What seizure/disease/epilepsy do we see 4-6 Hz bilateral polyspikes on the EEG? How do we treat it?
juvenile myoclonic epilepsy
treatment is lifelong, with valproate and lifestyle changes
What seizure/disease/epilepsy do we see with acute rheumatic fever and group A strep?
Sydenham chorea
What seizure/disease/epilepsy do we see a child given an antiemetic, then they have muscle contractions that get better with diphenhydramine?
dystonia
What is esophageal reflux that makes the babies arch their back and looks like a seizure?
sandifer syndrome
Ataxia onset at 2yrs versus ataxia onset @ 10+ yrs
2: ataxia tanglectasia
10+: Friedreich’s ataxia
What disease do we see Wednig Hoffman disease, and the anterior horn cells are affected, we see absent DTR, tongue fasciculations, and a weak cry in babies
spinal muscular atrophy (SMA)
What disease do we see trouble brushing hair or lifting things over head/shoulder, 1st sign is a heliotrope rash?
dermatomyositis
explain the difference between Becker and Duchenne muscular dystrophy?
Becker still has some functional dystrophin but Duchenne does not
What disease do we see craniosynostosis with limbs affected?
apert
When do we see an assymetrical moro reflex?
Erb Duchenne palsy
When do we see a loss of grip reflex in babies?
Klumpke’s palsy
What is TORCH (not what it stands for)
congenital infections common in babies, we test them for these
What brachial plexus lesion do we see: deficits in the deltoid muscle? damage done at the surgical neck of the humerus
damage to axillary nerve
What brachial plexus lesion do we see the triceps not working?
radial nerve at the axilaa
What brachial plexus lesion do we see that the triceps are working? damage is a midshaft fracture
radial nerve at the radial groove
What brachial plexus lesion do we see digits 2-3 affected and a loss of pronation? supracondylar fracture
median nerve at the elbow
What brachial plexus lesion do we see digits 2-3 messed up and the thumbs are also affected?
median nerve at the wrist
What brachial plexus lesion do we see digits 4-5 messed up but sensation in the palm is good?
ulnar nerve at the wrist
lesion do we see digits 4-5 messed up but sensation in the palm is also lost?
ulnar nerve at the elbow
ulnar nerve at the wrist is messed up. Name?
Guyon’s canal syndrome
ulnar nerve at the elbow is messed up. Name?
cubital tunnel syndrome
if there is a superior trunk lesion we have:
Erb duchenne (C5-C6)
If we have a lesion of the inferior trunk we have:
klumpke palsy (C8-T1)
What are the live vaccines for babies?
MMR, varicella, and rotavirus
What are the 4 adolescent vaccines?
HPV, Tdap, MCV4, MenB
What personality disorder is whimsical and magical? Think of Trelawney from Harry Potter
schizotypal personality disorder (cluster A)
What personality disorder makes you think of Sheldon from BBT? doesn’t care about social situations
schizoid personality disorder
What tumor?
Rosenthal fibers (corkscrew fibers); affects brainstem and cerebellum
pilocytic astrocytoma