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GnRH
protein/peptide released by the hypothalamus
promotes release of gonadotropins (FSH and LH) from anterior pituitary in males and females
Gonadotropin releasing hormone
GnRH
FSH
protein/peptide released by the anterior pituitary
stimulates sperm production in male testes and egg plus E2 in female ovaries
Follicle stimulating hormone
FSH
LH
protein/peptide released by the anterior pituitary
stimulates testosterone production in male testes and P4 production in ovaries
Luteinizing hormone
LH
T/DHT
steroid released by the male gonad (testes)
(androgen); promotes sperm production in seminiferous tubules
hair, muscle, bone growth. increase in sex drive
increases acne plus hirsutism in females
DHT
promotes prostate gland growth
Testosterone
T
Dihydrotestosterone
DHT
INHB
protein/peptide released by the male gonad (testes)
negative feedback to decrease/regulate sperm production (a future male contraceptive?)
Inhibin
INHB
E1
steroid released by the adrenal cortex
increases in menopause → less activity than E2
gonado corticoid
Estone
E1
E2
steroid released by the female gonad (ovary)
positive feedback in follicular phase (d1 to 14) to peak at ovulation; negative feedback in Luteal phase (d15 - 28)
low secretion during menses
more common estrogen during fertile years → synergizes with 5-HT during pregnancy
Estradiol
E2
E3
steroid released by placenta
lowest activity estrogen; used in menopause HRT (hormone replacement therapy)
Estriol
E3
P/P4
steroid released by the ovary and placenta
“hormone of gestation (pregnancy)”
promotes monthly uterine development
negative feedback in luteal phase and in gestation; part of LARC (along with injections, implant, IUD)
progesterone
P/P4
PRH
protein/peptide released by the hypothalamus
promotes release of PRL
Prolactin Releasing Hormone
PRH
DA
(aka, PIH)
catecholamine released by the hypothalamus (and GI tract)
reward/addiction, plus blocks PRL until parturition (birth)
Protein inhibitory hormone
DA (aka , PIH)
PRL
protein/peptide released by the anterior pituitary
promotes milk productin in mammary glands during lactation
Prolactin
PRL
OT/OXT
protein/peptide released by posterior pituitary
promotes muscle contraction during birth and milk let down (orgasms)
“cuddle” hormone = love/bonding
oxytocin
OT/OXT
PG
lipid/NT released by local tissues in reproductive tract
promotes muscle contraction during birth and menses (released by damaged tissue)
causes pain (binds to nociceptors) and possibly dysmenorrhea (difficult menses) or PMS
prostaglandin
PG
hCG
peptide/protein released by the placenta
helps to maintain early pregnancy (and causes nausea/emesis) - used in pregnancy tests
human chorionic gonadotropin
hCG
hPL/hcs
protein/peptide released by the placenta
shifts glucose to the fetus from the mom (may contribute to gestational diabetes)
human placental lactogen
(aka, human chorionic somatomammatropin)
hPL/hcs
parasympathetic nervous system
nervous system that causes erection
sympathetic nervous system
nervous system that causes ejaculation
.
the ANS works together in reproduction
NO (nitric oxide)
gas that causes vasodilation to enable erection
does this by blocking PDES enzyme to store the Ca (ion of contraction) into the SR which will continue smooth muscle relaxation
DA
neurotransmitter that is released to reward mating and feeding (do it again!)
puberty
when does fertility (and spermatogenesis) being?
continuously
How is sperm made (pattern)?
.
males have breasts, penis (clitoris), gonads, GnRH, FSH, LH, T, E2, Gametes