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For what purpose are radiopharmaceuticals administered?
To diagnose, treat and assess pathologies specific to an organ or anatomical function
What is a kit?
A vial containing pharmaceuticals which when combined with radionuclides become radiopharmaceuticals
Which nuclear medicine imaging procedure is used to asess perfusion to the heart?
Myocardial perfusion scan (MPS)
What does the term ‘hot’ mean with respect to radioactivity?
High concentration of radioactivity ('is radioactive')
List the challenges associated with nuclear medicine as an imaging modality. (6)
Radiation safety
Patient compliance
Costs
Availability of radioactivity
Rise in non-ionising imaging modalities
Availability of scanners to patients
Who developed the first gamma camera in 1957?
Hal Anger
What is the name for the imaging unit that combines a nuclear medicine gamma camera with CT?
SPECT/CT
Name the different types of imaging devices used in nuclear medicine. (8)
- SPECT
- SPECT/CT
- Dedicated scanners
- Portable gamma cameras
- Intra-operative gamma cameras
- PET/CT
- PET/MRI
- BMD
List the different acquisition types that can be acquired on a nuclear medicine gamma camera. (6)
- Dynamic imaging
- Static imaging
- Whole body imaging
- Cardiac-gated imaging
- SPECT
- SPECT/CT
What are the benefits of performing SPECT/CT procedures? (4)
- Versatile in its regions that can be imaged
- Allows greater accuracy in anatomical localisation
- Improves specificity and sensitivity of the modality
- Can perform standalone NM scans and standaloneT scans
What are dynamic images?
Continuous images acquired over set period to assess blood flow, gastric-emptying rates and renal excretion
What is the newest modality to be utilised in nuclear medicine
PET/MRI
What does PET stand for?
Positron emission tomography
Following a diagnostic nuclear medicine procedure can a patient go on to have additional medical imaging procedures? Why or why not?
Nuclear medicine is considered a ________ imaging modality.
Functional
How does cardiac gating work in nuclear medicine?
The gating process breaks each cardiac cycle into a series of bins to synchronize the imaging with the heart's phases, allowing for more accurate assessment of cardiac perfusion and function.
Name two nuclear medicine procedures where the radiopharmaceutical is delivered orally.
Colonic transit study
Gastric emptying study
What radionuclide can be used to treat papillary thyroid cancer?
Iodine-131
In what year & by who were gamma rays discovered?
Paul Villard, 1900
What nuclear medicine procedure is used to evaluate PE?
Ventilation perfusion (VQ) scan
How has nuclear medicine improved its ability to display anatomical detail?
Hybrid imaging combines functional and anatomical information to allow more accurate localisation of
True or false, all nuclear medicine procedures involve imaging.
False
Following a diagnostic nuclear medicine procedure can a patient go on to have additional medical imaging procedures? Why or why not?
Yes, as the decay of the radiopharmaceutical does not impact other imaging modalities.
What does the term SPECT stand for? And provide a brief explanation of this image acquisition method.
Single photon emission computed tomography uses gamma photons that are given off from the decay of a radiopharmaceutical after its administration into the patient. The gamma camera rotates around the patient to absorb the varying signal intensities of gamma photons being emitted from the patient and provide three-dimensional views of the anatomy.