Midterm 2.3 (Compounding)

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49 Terms

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Electrolytes

Used for proper enzymatic and energy conserving or expending reactions within the body (e.g. sodium, potassium, magnesium, calcium, chloride, phosphate)

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Fat soluble vitamins

  • are absorbed from the intestinal tract along with lipids in th presence of bile

  • can be stored by the body, so these vitamins a higher potential for toxicity of intake is excessive

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Water soluble vitamins

These vitamins cannot be stored by the body in large quantities and are rapidly absorbed

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Patch through hatch

It is the window where materials can be huddled through

<p>It is the window where materials can be huddled through</p>
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Clean room

specially constructed enclosed room in which the:

  • air supply

  • air distribution

  • air pattern

  • flow pattern

  • room pressure

  • temperature

  • humidity

    • are controlled to meet appropriate cleanliness level

<p>specially constructed enclosed room in which the:</p><ul><li><p class="has-focus">air supply</p></li><li><p class="has-focus">air distribution</p></li><li><p class="has-focus">air pattern</p></li><li><p class="has-focus">flow pattern</p></li><li><p class="has-focus">room pressure</p></li><li><p class="has-focus">temperature</p></li><li><p class="has-focus">humidity</p><ul><li><p class="has-focus">are controlled to meet appropriate cleanliness level</p></li></ul></li></ul><p></p>
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High efficiency particulate air filter

It is composed of pleats of filter medium separated by rigid sheets of corrugated paper or aluminum foil that direct the flow of air forced through the filter in a uniform parallel flow.

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0.3 um

Hepa filter removes 99.97% of all air particles (what size) or larger.

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Dioctyl Phthalate (DOP) Test

This test is used to test he integrity of the HEPA filter

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aerosols

The Hepa filter removes particulates, generally called —, such as micro-organisms, from the air.

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True

True or false

  • The HEPA filter does not remove vapors or gases

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Laminar Air Flow Hood (LAFH)

  • an equipment that makes use of a High Efficiency Particulate Air (HEPA) filtration

  • may be in a horizontal, vertical or convergent flow type

<ul><li><p>an equipment that makes use of a High Efficiency Particulate Air (HEPA) filtration </p></li><li><p class="has-focus">may be in a horizontal, vertical or convergent flow type</p></li></ul><p></p>
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Class 100 LAFC

What LAFH is required for the aseptic manufacture of sterile preparations?

  • Meaning there should be no more than 100 particles over cubic output

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Unidirectionaly velocity

<p></p>
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True

True or false

<p>True or false</p><p class="has-focus"></p>
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90 linear feet per minute

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Critical work surface

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Horizontal laminar air flowhood

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Vertical floww laminar air flow hood (BSC)

<p></p>
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Read

Answer read

<p>Answer read </p>
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Turbulent flow

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six

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Down time

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True

True or false

  • Before use, all interior working surfaces of the laminar flow hood should be: Cleaned back to front away from hepa filter

<p>True or false</p><ul><li><p>Before use, all interior working surfaces of the laminar flow hood should be: Cleaned back to front away from hepa filter</p></li></ul><p></p>
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Positive pressure rooms

  • These rooms are provided primarily for patients with the compromised immune system.

  • Air will flow out of the room instead of in

<ul><li><p>These rooms are provided primarily for patients with the compromised immune system.</p></li><li><p class="has-focus">Air will flow out of the room instead of in</p></li></ul><p></p>
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Negative pressure room

these rooms are provided primarily for patients with airborne contagious diseases such as tuberculosis, measles or chickenpox to prevent crosscontamination from room to room of airborne diseases/

<p>these rooms are provided primarily for patients with airborne contagious diseases such as tuberculosis, measles or chickenpox to prevent crosscontamination from room to room of airborne diseases/</p>
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  • Gauge 19 - viscous liquids

  • Gauge 21 - mobile liquids

  • Gauge 23 - vent needed

Needles used in compounding:

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  • Needles

  • IV Fluids

  • Ampoule/vial

The materials that should be seen in an LAFH:

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  • Incorporated

  • Non incorporated

There are two types of TPN

1. - with additional components

2. - only the bag

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  • Hub

  • Shaft

  • Bevel heel

  • Bevel

  • Bevel tip

Parts of a nedle

<p>Parts of a nedle</p>
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Gauge

It means the diameter/thickness of the needle and not the length

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Vent needles

What needles are used when inducing air into a vial

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  • PVC Polyvinyl Chloride

  • EVA Ethylvinyl acetate

Types of SILICON BASED containers for IV Fluids:

1. — - used for other IV Fluids excepts TPN, because they contain plasticizers

2. — - used for TPN ONLY

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  • Flat end (Lip)

  • Plunger

  • Top collar

  • Plunger rpiston

  • Final edge of plunger piston

  • Barrel

  • Calibration marks

  • Luer lok tip

Parts of a syringe

<p>Parts of a syringe </p>
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True

True or false

  • Even if the IV fluid is non incorporated (non reconstituted), the additives should still be placed on the label

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Aseptic technique

refers to the ability of personnel to handle sterile components in a clean environment and without introducing microorganism into the product

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  • 4% chlorhexidine gluconate

  • Alcohol (isopropyl)

What are two types of hand washing agents

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  • 4% chlorhexidine gluconate

  • Alcohol (isopropyl)

Hand washing agents

  • Has good residual effect

  • Has little residual effect; used as hand disinfectant

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  • Evaporative dryer

  • Non linting wipers

Hands should be dried using — or —

<p>Hands should be dried using — or —</p>
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  • Isopropyl alcohol or 70% ethanol

  • Pass through hatch/trolley

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  • Luer lok tip

  • Plunger

What parts of the plunger should never be touched

<p>What parts of the plunger should never be touched</p>
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  • Luer lock

  • Luer slip

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Hub

It is where the needle attaches to the syringe tip and allows the fluid in the syringe barrel

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Bevel

It is the slanted part of the needle; allows for smooth insertions through stoppers and ports with minimal coring

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  • Gauge

  • Length

Needle size is determined by two numbers

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False

True or false

  • The smaller the gauge number, the finer the diameters of the needle’s bore is

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Inches

Needle length is measured in what unit

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Coring

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Recall

Recall Procedures in aseptic preparation and administration of IV admixtures

<p>Recall Procedures in aseptic preparation and administration of IV admixtures</p>
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  • Sterile gown

  • Sterile gloves

  • Snugly fit headcap

  • Surgical face mask

Safety: Handling of Parenterals

  • Protective clothing: