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discharge, dysuria, pelvic pain, cervical friability; 80% asymptomatic
What is the presentation for chlamydia?
Nucleic Acid Amplification Tests (NAATs)
Use of PCR to amplify DNA of an unknown microorganism that cannot be cultured
NAAT with urine clean catch
What is the preferred way to diagnose chlamydia and gonorrhea?
1 g PO azythromycin single dose; 100 mg doxycycline PO bid x 7 days (not in pregnant or possibility of pregnancy)
What is the treatment for chlamydia?
notify partners; avoid sexual contact during and for 7 days after treatment
What is the teaching that should go along with a diagnosis of chlamydia?
gonorrhea
bacterial STI that is most commonly spread from male to female than opposite; women have more problems with joint infection in advanced infections
conjunctivitis and blindness
What can exposure to gonorrhea from an infected mother cause in an infant?
rocephin 250 mg IM once plus azithromycin 1g PO once
What is the treatment plan for gonorrhea?
acyclovir 400 mg po tid x 7-10 days
What is the recommended treatment for an outbreak of HSV?
> 6 recurrences per year
When is daily suppressive therapy for HSV recommended?
acyclovir 400 mg bid x 1 year
What is the recommended suppressive therapy for HSV when indicated?
Trichloroacetic acid
What is the recommended treatment for genital warts associated with HPV?
chancre
a firm, round, painless genital or anal ulcer with a clean based and indurated margins that occurs with syphillis
chancre, localized lymphadenopathy, 3 weeks duration which resolves without therapy
What are the signs of a primary syphillis presentation?
non-pruritic skin rash often involving the soles of the feet and palms of the hands; painless white mucous membrane lesions; flu like fever, lympadenopathy, sore throat, hair loss, headaches, weight loss, muscle aches, fatigue; resolution without treatment possible
What are the signs of a secondary syphilis presentation?
gumma, CV functional problems, slow deterioration of nerve function
What are the s/s of tertiary syphilis presentation?
gumma
a characteristic soft, gummy lesion caused by bacteria that invade organs throughout the body; found in the tertiary stage of syphilis; found in various organs, most notably the liver
use of one test is insufficient for diagnosis
What is important to remember when assessing for syphilis?
RPR, VRDL
What are the nontreponemal tests used for syphilis?
PCN G 2.4 million units IM single dose; peds 50,000 units/kg up to adult dose
What is the plan for the treatment of primary syphilis?
PCN G 7.2 million units IM total over 3 doses in 1 week intervals
What is the plan for the treatment of late syphilis?
tetracycline or doxycycline
What meds may be used in the treatment of syphilis in patients that have a PCN hypersensitivity?
dysuria, itching, irritation, cervical motion tenderness, vaginal discharge may be yellow green (occasional frothy); cervical petechial hemorrhages (strawberry cervix)
What is found on presentation of trichomoniasis?
metronidazole or tinidazole 2gm po single dose
What is the recommended treatment for trichomoniasis?
vaginal antifungal
What is the recommended treatment for trichomoniasis in women in the first trimester of pregnancy?
flu like symptoms, night sweats, decreased CD4 counts that can rebound and remain symptom free for years
What symptoms may occur within the first 2-6 weeks after HIV infection?
CD4 count < 200, the appearance of one or more opportunistic infections
What is the criteria for the diagnosis of AIDS vs HIV?
CBC, CMP, lipids, STI panel, Hep A, B, and C; TB test, confirmatory test
What are the labs included in the workup of a newly diagnosed HIV patient?
ELISA confirmed by Western Blot
What is the recommended testing protocol for HIV?
HAART, therapy for OIs and malignancies, prophylaxis for OIs based on CD4 count, immunizations
What is included in the treatment of HIV?
Truvada
What is the new drug used as pre exposure prophylaxis for HIV?
ART and follow guidelines for repeat testing (6,3,6,1)
What is the post exposure prophylaxis for HIV?