[PF1] ENDOCRINE - Ovaries

Which region of the ovary makes up most of its volume and contains many ovarian follicles?

Cortex/Cortical Region

Which region of the ovary contains loose connective tissue and blood vessels?

Medulla/Medullary Region

Which ovarian follicle layer consists of stratified cuboidal epithelium composed of granulosa cells?

Granulosa Cell Layer

Which ovarian follicle layer surrounds the follicle and secretes estradiol and liquor folliculi?

Granulosa Cell Layer

Which follicular layer contains steroid-producing cells that secrete androstenedione?

Theca Interna

Which layer lies outside the granulosa cell layer and is separated by a thin basement membrane?

Theca Interna

Which hormone is produced by the granulosa cells through aromatization of androstenedione?

Estradiol

Consists of large, polygonal cells with pale-staining cytoplasm (due to presence of lipid droplets)

Theca Interna

Androstenedione passes through basement membrane to granulosa layer where aromatase converts it to

Estradiol

Outermost layer which resembles a layer of flattened fibroblasts and smooth muscle cells

Theca Externa

Theca Externa blends gradually with the ___

Stroma

What separates Theca Interna and Granulosa Cell Layer?

Basement Membrane

What is a large, temporary endocrine gland mainly formed out of granulosa lutein cells and theca lutein cells

Corpus Luteum

What cell has densely stained cytoplasm with larger lipid droplets?

Theca Lutein Cells

What cell has an ovoid nucleus with a single nucleolus?

Theca Lutein Cells

What cell is half the size of granulosa lutein cells?

Theca Lutein Cells

What cell is derived from the theca interna?

Theca Lutein Cells

What cell secretes progesterone and androstenedione due to effects of LH?

Theca Lutein Cells

What cell is located on the periphery of glandular epithelium, external to granulosa lutein cells?

Theca Lutein Cells

What cell has eosinophilic nucleoplasm due to numerous small lipid droplets?

Granulosa Lutein Cells

What cell has a larger and more spherical nucleus with one or two nucleoli?

Granulosa Lutein Cells

What cell is derived from the granulosa cell layer?

Granulosa Lutein Cells

What cell's main function is to convert androstenedione into estradiol?

Granulosa Lutein Cells

Granulosa Lutein Cells converts androstenedione into estradiol via ?

aromatase enzyme

What cell is 20% of the Corpus Luteum?

Theca Lutein Cells

What cell is 80% of the Corpus Luteum?

Granulosa Lutein Cells