Inflammatory reponse

inflammation

immune systems reponse to harmful stimuli and acts by removing the stimulus and initiating the healing process

Physical signs

redness, swelling, heat, pain and pus

Vascular stage

involves blood vessels, damaged cells release cytokines and prostagladins that attract neutrophils, and mast cells release histamines, causing vasodilation and increase permability

cellular stage

involves immune cells, migration of neutrophils to infection site followed by macrophages, release signals that attract more phagocytes that attack pathogens

resolution stage

when inflammation stops and normal stage is restored, includes reversal of process that produced inflammation

Signs

Vasodilation causes increased blood flow resulting in redness and heat, also causes increase of fluids causing swelling, pus is due to dead phagocytes and cell debris