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Heartburn Risk Factors from Food/Alcohol
- Food: Alcohol, caffeine, carbonated drinks, citrus fruit, coffee, fatty foods, spicy foods
- Medications: Anticholinergic agents, Aspirin, Calcium channel blockers
Other Heartburn Risk Factors
Emotion, exercise, stress, smoking, tight-fitting clothing, pregnancy, lying down after eating
Nonpharmacologic Therapy
- Symptom diary
- Wear loose-fitting clothing
- Avoid eating large meals
- If nocturnal: avoid laying down within 3 hours of meal, elevate head of the bed
- Stop or reduce smoking
- Lose weight if overweight
- Avoid use of aggravating medications if possible
Antacids dosing/administration
product-specific recommended doses at onset of symptoms
- May be repeated in 1-2 hours if needed
Antacids Onset
Less than 5 min
Antacids Duration
20-30 min
Antacids Side effects
- usually well tolerated
- aluminum: constipation
- calcium: belching/gas
- magnesium: diarrhea
- sodium bicarbonate: belching/gas
Antacids Follow up
Reevaluate if using more than twice a week
Antacids Recommendation
- Aspirin + sodium bicarbonate + citric acid (Alka-Seltzer)
- Calcium carbonate (Tums)
- Calcium carbonate + magnesium hydroxide (Rolaids)
H2RAs Dose/Administration
- Take one tablet twice a day
- May take at onset of symptoms orr 30-60 min before anticipated heartburn
H2RAs Max in 24 hours
Max 2 tablets in 24 hours
H2RAs onset
30-45 min
H2RAs Duration
4-12 hours
H2RAs Side Effects
Usually well tolerated
- Watch for headache, diarrhea, constipation, dizziness
H2RAs Follow up
If routine self-treatment is needed for more than 2 weeks - refer
H2RAs Recommendation
- Famotidine (Pepcid AC)
H2RA + Antacid Dose/Administration
Chew 1 tablet daily 15-60 min before symptoms are expected
H2RA + Antacid max in 24 hours
Max 2 tablets in 24 hours
H2RA + Antacid Onset
Less than 3 min
H2RA + Antacid Duration
8-12 hours
H2RA + Antacid Side Effects
- gas, belching
- products with calcium: constipation
- products with magnesium: may cause diarrhea
H2RA + Antacid Follow Up
If routine self treatment is needed for more than 2 weeks = refer
PPIs Dose/Administration
Take 1 tablet/capsule 30-60 min before a meal once daily, EVERY day
- Do not crush or chew
- Take for a maximum of 14 days
- Do not use more than once every 4 months
PPIs Onset
May occur on 1-3 hours, may take 1-4 days for complete relief
PPIs Duration
12-24 hours
PPIs Side Effects
Well tolerated
- Watch for headache, abdominal pain, diarrhea, constipation, gas
PPIs Follow Up
If heartburn continues during treatment, continues for more than 2 weeks, recurs within 4 months = refer
PPIs Recommendation
- Esomeprazole
- Omeprazole
Bismuth Subsalicylate Dose/Administration
Pepto-Bismol Liquid: Take 30 mL every 30 min as needed
- Do not use if aspirin allergy **
Bismuth Subsalicylate Onset
less than 5 min
Bismuth Subsalicylate Duration
Lasts 30 min
Bismuth Subsalicylate Side Effects
Dark discoloration of tongue and stool
Bismuth Subsalicylate Follow Up
Re-evaluate if using more than twice a week
Bismuth Subsalicylate Recommendation
Maalox, Pepto-Bismol