MedChem Final Drugs

Catecholamine-non selective

dopamine, norepinephrine, epinephrine, dipivefrin

non selective agonist

dobutamine

selective a1 agonist

phenylephrine, metaraminol, methoxamine, midodrine, propylhexedrine

non selective a- agonist

Naphazoline

imidazolines a1 agonist

tetryzoline, oxymetazoline, Xylometazoline

Selective a2 agonist guianidines

Clonidine, brimonidine, tizanidine, guafacine, guanabenz, apraclonidine

Selective a2 agonist imidazoles/imadazolidine

dexmedetomidine, medetomidine

Selective a2 agonist imadazoline

Lofexidine hydrochloride

non selective b agonist

isoproterenol, Isoetharine

Selective b2 agonist SABA

metaproterenol, Terbutaline, albuterol, levalbuterol, pirbuterol

Selective b2 agonist LABA

formoterol, salmeterol, vilanterol, arformoterol, indaceterol, ritoridine

Selective b3 agonist

mirabegron

Mixed acting sympathomimetics

Pseudoephedrine, ephedrine

Indirect acting

amphetamine, dextroamphetamine, methamphetamine, lisdexamfetamine, hydroxyamphetamine, methylphenidate (NDRI)

a blockers/ a antagonist b-haloethylamines

phenoxybenzamine

a blockers/ a antagonist Imidazoline

phentolamine, Priscoline

a antagonist to treat benign prostate hyperplasia (BPH)/ Hypertension except sulfonamide (quinazolines)

doxazosin, alfuzosin, terazosin, prazosin, tamulosin

non selective b blockers/ b antagonist

propranolol, nadolol, timolol, pindolol, labetolol

selective b1 antagonist

metoprolol, atenolol, esmolol, acebutolol, carvedilol, carteolol, levobunolol, betaxolol, bisoprolol, nebivolol, celiprolol, sotalol

Parkinson’s disease levodopa therapy to increase dopamine biosynthesis

levodopa, carbidopa, foslevodopa, foscarbidopa

Dopamine receptor agonist ergot alkaloids

Pergolide (pets only), bromocriptine, cabergoline

Dopamine receptor agonist morphine derivative

apomorphine

dopamine receptor agonist- parkinson’s disease/ restless leg syndrome

pramipexole, ropinirole, rotigotine

drugs that increase dopamine release

amantadine

drugs affecting catecholamine biosynthesis

metyrosine, metyldopa

drugs affecting catecholamine storage and release

reserpine, bretylium

monoamine oxidase b inhibitors

selegiline, rasagiline, safinamide

Catecholamine o-methyl transferase inhibitors

tolcapone, entacapone, opicapone