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act as chemical messengers through the bloodstream to target cells, bind and trigger biological response
cell receptors
proteins on or inside target cells that bind to specific molecules
negative feedback.
It forms a hormone-receptor influencing gene expression and protein synthesis.
upregulation
increase in the number of receptors on a cell
downregulation
decrease in receptor number
increases cell reproduction, enhances protein synthesis, and promotes lipolysis.
reabsorption in the kidneys, concentrating urine and decreasing water loss.
stimulating osteoclast activity in bones and enhancing calcium reabsorption in the kidneys.
stimulates the adrenal cortex to produce cortisol, which is important for stress response and metabolism.
hypothalamic
l increases glucose production, suppresses the immune system, and helps the body respond to stress.
lowers blood glucose by promoting its uptake into cells and storing it as glycogen.
raises blood glucose levels by stimulating the liver to release stored glucose.
an autoimmune destruction of insulin-producing beta cells in the pancreas.
insulin resistance and eventual beta-cell dysfunction, often linked to obesity and poor lifestyle choices.
low oxygen levels in the blood, which stimulates the release of erythropoietin (EPO).
percentage of blood volume occupied by red blood cells.
120 days
fragmentation of megakaryocytes live up to 10 days
when the ventricles contract.
buildup of fatty deposits on the inner walls of arteries, which can lead to reduced blood flow and increased risk of cardiovascular events.
medulla oblongata of the brainstem.
What is the function of the systemic circuit?
carries oxygenated blood from the left ventricle to the body tissues and returns deoxygenated blood to the right atrium.
Right Atrium
Receives deoxygenated blood from the vena cava.
Right Ventricle
Pumps deoxygenated blood to the lungs via the pulmonary artery.
left Atrium
Receives oxygenated blood from the lungs.
left Ventricle
pumps oxygenated blood to the body via the aorta.
what are the av valves
Tricuspid Valve Bicuspid valve
blood flow
Vena Cava (Superior and Inferior) → Right Atrium → Tricuspid Valve → Right Ventricle → Pulmonary Valve → Pulmonary Artery → Lungs
Chambers Containing Oxygen-Poor Blood
Right Atrium and Right Ventricle