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promote remineralization
inhibit demineralization
bacterial interaction
fluoride acts in 3 ways:
hydroxyl (OH)
Fluoride ions replace _______ ions in hydroxyapatite to form fluorapatite in the tooth enamel
5.5
In a cariogenic challenge, when the pH drops below ___, the biofilm fluid becomes undersaturated with phosphate ion and enamel dissolves to restore balance
4.5
when fluoride is incorporated into demineralized enamel, subsequent demineralization in enamel now can only happen when the pH is below ____
tooth development
when does fluorosis occur?
0.7 ppm F
what is the current ADA recommendation for water?
1,000 ppm - 1,500 ppm F
how much fluoride is in over the counter toothpaste?
5,000 ppm NaF
how much fluoride is in prescription toothpaste?
0.05% NaF
for high risk patients, daily rinse should contain what % of Rx fluoride?
0.2% NaF
for high risk patients, weekly rinse should contain what % of Rx fluoride?
22,600ppm F (5% NaF)
how much fluoride is in topical varnish?
12,300 ppm (1.23% NaF)
how much fluoride is in fluoride gel?
44,800 ppm (38% NaF)
how much fluoride is in SDF?
6 years
mouth rinse is not recommended for children under the age of:
acute
nausea and vomiting is a ________ effect of fluoride toxicity
acute
hypocalcemia is a ________ effect of fluoride toxicity
acute
tetany is a ________ effect of fluoride toxicity
acute
mixed metabolic and respiratory acidosis is a ________ effect of fluoride toxicity
acute
coma and convulsions leading to death is a ________ effect of fluoride toxicity
chronic
dental fluorosis is a ________ effect of fluoride toxicity
chronic
skeletal fluorosis is a ________ effect of fluoride toxicity
chronic
hypersensitivity reactions is a ________ effect of fluoride toxicity
chronic
dyspepsia is a ________ effect of fluoride toxicity
chronic
numbness is a ________ effect of fluoride toxicity
chronic
birth defects and cancer is a ________ effect of fluoride toxicity
0.05-0.07mg F/kg body weight
what is the optimal dose of fluoride for children and adults?
5 mg F/kg body weight
what is the toxic dose of fluoride for children and adults?
32 mg F/kg body weight
what is the lethal dose of fluoride for children?
64 mg F/kg body weight
what is the lethal dose of fluoride for adults?
milk, observation
if a child ingests less than 5 mg/kg of fluoride, what is the treatment?
hospitalization
if a child ingests more than 5 mg/kg of fluoride, what is the treatment?
IMMEDIATE hospitalization
if a child ingests less than 15 mg/kg of fluoride, what is the treatment?
concentration of F
weight of toothpaste ingested (gm)
weight of child (kg)
symptoms
what 4 pieces of information do you need to assess the severity of a fluoride toxicity?
2.26% fluoride varnish or 1.23% fluoride gel (in office)
prescription-strength, home-use 0.5% fluoride gel or paste or 0.09% fluoride mouth-rinse
For patients 6 years or older at risk of developing dental caries you would recommend:
Only 2.26% fluoride varnish (in office)
For patients under 6 years old at risk of developing dental caries you would recommend:
true
t/f: Sealants with NaF varnish is more effective than just NaF varnish or just sealants.