Examples of resistance in gram- bacteria/yeasts/fungi

4 - Fungi (Yeasts, Molds & Mushrooms)

Learn: W.B. Yeats quotes nd

2.5 - Wheat and Wheat Products: Yeast Breads

Art of interviewing In an interview, what factor do we need to consider? Social Economic Cultural How does the provider pick up on subtle ques? Shifts in body language in addition to spoken word Patients will tell you what is wrong with them if you ask the right questions Questions Open Ended OLDCARTS Don't use medical jargon Confrontation Watch for subtle ques "You look upset discussing _____, lets talk about it" Points out something striking about the patient's behavior or statement ○ Directs the patient's attention to something of which they may or may not be aware of ○ You look upset, you sound uncomfortable about that, Is there a reason you look away from me as you speak What does good communication improve? Health outcomes by resolving symptoms and reducing patient's psychogical distress and anxiety 85% of all malpractice lawsuits are based on poor communication skills What should we implement during an interview? ACTIVE LISTENING Watch their body language, tone, eye contact, speech and spoken word Understanding of what is being said, body language and other non verbal ques Symptom SUBJECTIVE ~What the patient feels ~Described by the patient Can be influenced by culture, intelligence and socioeconomic background Constitutional Symptom Fevers, Chills, Weight Gain, Weight Loss Effect all symptoms Sign OBJECTIVE What the observer finds on the assessment Crackles, dry skin, bruising What are the basic interviewing techniques? Questions Silence Facilitation Confrontation Interpretation Reflection Support Transitions Silence Silence is ok, but limit to 2 minutes or less If a patient is silent, you are silent Can restart the conversation with, "What are you thinking about?" Should never be used with the overtalkative patients ○ Can indicate interest and support ○ Don't allow more than 2 minutes of silence ○ Ok to ask: What are you thinking about? You were saying? These things are hard to think about Facilitation Keeps the conversation going "Tell me more about..." Encourages a patient to continue talking without controlling the direction of the conversation ○ Verbal and nonverbal communication that encourages the patient to keep talking ○ Go on, Tell me more, uh huh, And then Interpretation Based on inference "It sounds as if you are afraid...." Based on inference rather than observation ○ The provider interprets the patient's behavior, encouraging the patient to observe their own role in the problem. ○ You seem happy about that, Are you afraid you've done something wrong?, I wonder if your ____ is related to _____ Reflection Repeat part of the statement made by the patient Pt: "I haven't worked since 2016" APRN: "You haven't worked since 2016? Lets talk about that" A response that mirrors what the patient has just expressed ○ Patient: I am nervous about starting a new medication ■ Provider: Nervous about starting a new medication? Support Build a trusting relationship with the patient by using reassurance and empathy Shows an interest in or understanding of a patient ○ I understand ■ Reassurance ● A response that conveys to the patient that the interviewer understands what has been talked about ● That's great you were able to stop smoking, I am glad you came in today - we are going to help you ■ Empathy ● Response that recognizes a patient's feelings and does not criticize ● It's an understand, not an emotional state of sympathy ● I know it is not easy ______, I'm sure ______ has caused you a large amount of anxiety Transitions "Now I am going to ask you questions about..." Used as guides to allow the patient to better understand the logic of the interviewers questions in order to have a good flow to change the topic ○ I am now going to ask you questions about ______, Now let's talk about______ What does a past medical hx all include? General state of overall health Past Illnesses Hospitalizations Surgeries Prior injuries and accidents Allergies Current Medications Diet Sleep Patterns Immunizations Substance Abuse Complementary / Alternative Therapies What is sensitivity? How good a test is at identifying people who truly have the disease True Positive - Positive results are convincing RULE OUT = SnNout Sensitive test + Negative = disease OUT What is specificity How well a test does at correctly identifying people who are well True Negative - negative result is convincing RULE IN = SpPin Specific test + Positive = disease IN What is a functional capacity assessment? Asses geriatric patients abilities to perform activities of daily living (ADLs) -Self Care -Instrumental -Mobility -Timed Get Up and Go test Self Care ADLs Dressing Bathing Transferring from bed to chair Toileting Grooming Feeding oneself Instrumental ADLs Meal Preparation Managing Finances Use the phone Taking Meds Doing Housework Shopping Managing Transport Mobility ADLs Walking from room to room Climbing stairs Walking outdoors What is the timed get up and go test? Rise from chair, walk 10 feet, turn around, walk back to chair, turn and sit down Should be completed in 10 seconds or less If greater than 20 seconds, patient will need further evaluation What is the strongest predictor of future disability and death? Gait What should we be assessing in the elderly in relation to ADLs? # of falls in the last year Gender Identity One's internal sense of gender at a given time How a person feels and identifies themselves in terms of gender such as being a boy, girl or another gender Sexual Orientation The presence and/or object of a person's romantic, sexual, physical or spiritual attractions Who someone is attracted to or has romantic feeing towards ■ Same gender, different gender, more than one gender Alternative Medicine Systems Complete systems of health care that developed separately from Western/conventional medicine i. Traditional Chinese Medicine ii. Traditional Indigenous Healing Practices iii. Homeopathic Medicine Ayurvedic - translates to knowledge of life, origin = India Mind-Body Interventions Techniques that use the mind to help improve physical health and well-being Biofeedback Yoga / Meditation / Deep Breathing Prayer Tai Chi Biologically Based Therapies Natural substances or products from nature to improve health or treat illness Vitamins Herbal Products Probiotics Dietary Supplements Specialty Diets Manipulative and Body Physical movement, pressure, or hands-on techniques to help the body feel better or function better Chiropractic Osteopathy Reflexology / Massage Therapy Energy Therapies Energy fields in or around the body can be influenced to improve health or well-being Biofield therapy ~Intended to affect a patient's energy field for the purpose of healing by having a healer place their hands in or through them; the therapist's healing force restores the patient -Reiki -Therapeutic Touch Bioelectromagnetic based therapies ~Involve the unconventional use of electromagnetic fields. -Positioning external magnetic fields near or around the person, usually by placing magnets on the body, into clothing, or in mattresses Acupuncture -Traditional Chinese medicine in which thin needles are placed into the body to allow qi (energy) to flow unimpeded What is Yin & Yang? 2 opposite yet connected forces that exist in nature and the body They work together to maintain balance and harmony Yin Cooler Darker Quieter Slower Passive Associated with Rest Earth Moon Night Water Femininity Cold Yang Warmer Brighter Active Faster Masculinity Associated with Activity ■ Day, Heat, Light, Movement What is the goal of Yin & Yang? To Remain Healthy: ○ Maintaining a proper balance between yin and yang ○ Neither is considered completely good or bad ○ Both are necessary and work together What is the goal of Chinese Medicine? Not only cure disease, but keep people well Disease means failure in prevention of health care Health is a shared responsibility between the patient and provider Chinese medicine treats the patient as a whole rather than separate systems Preserving health, curing disease of mind, body and spirit The mind can help direct your body's energy toward healing and recovery Disharmony ■ Provides framework to help aid in healing ■ Ex: Patient doesn't catch the flu, develops disharmony. Abx, acupuncture or herbs can help to redevelop harmony What 2 techniques do the Chinese look at to diagnose? Tongue Pulse Assessment Tongue Assessment Believed to be a clear indicator of disharmony Color, Shape, Moisture, Coating, Thickness, Cracks & Texture of the tongue Pulse Assessment Disharmonies of the body have effects on the pulse ● Divided into 3 sections ○ Cun ■ Closest to the wrist ○ Guan ■ Second position ○ Chi ■ 3rd position, furthest from the wrist Left wrist (yin) ■ Heart, liver and kidney Right Wrist (yang) ■ Lungs, spleen and kidney Special Considerations for Peds: Head Palpable Anterior and Posterior Fontanelles Special Considerations for Peds: Eyes Inspecting for red reflex Special Considerations for Peds: Mouth Inspect for oral thrush and geographic tongue Special Considerations for Peds: Genitalia Inspect for hypospadias (males), diaper dermatitis, vaginal yeast Special Considerations for Peds: Hip Dystocia Perform Barlow and Ortolani Maneuvers Assess for normal newborn primitive reflexes Special Considerations for teens Assess Tanner Stages for breast tissue and genitals Can ask parents to step out of the room for the exam to allow you to ask further personal questions. The parents can refuse, although most are happy to step out If the parent does agree, do not continue with further examination until another medical witness is in the room with you Additional questions for teens include social history, illegal drug use, sexuality, suicide/depression screening and safety at home Billing and Coding Current Procedure Terminology (CPT) International Classification of Disease (ICD) Current Procedure Terminology (CPT) -Codes used to document many of the medical procedures performed in a medical office -Services and procedures provided 1. Evaluation and Management 2. Performance and Measurement 3.Emerging Medical Terminology International Classification of Disease (ICD) Explains the reason for the services ○ Classifies diseases and injuries and is used to track mortality and morbidity statistics ○ Assigned to identify the diagnosis, system, condition, problem, complaint or other reason for the encounter Bias An unfair or one sided opinion that can influence how someone thinks or acts Implicit Bias Unconscious attitudes or beliefs about people that can affect how we treat or judge them without realizing it Explicit Bias Conscious and intentional opinions to beliefs about a person or group that can lead to unfair treatment Race Groups of people based on physical traits, national origin and ancestry ■ Skin color, different features Ancestery ○ People, families and backgrounds one comes from ○ Genealogic history, understanding of one's genetic heritage Racial Bias An unfair or one sided opinion/judgement about someone based on their race Racism Treating someone unfairly, badly, negatively because of their race Scientific Racism The false idea that science proves some races are better, smarter or more capable than others Belief of biological evidence of racial inferiority/superiority Example: Black people are biologically different and inferior to white people Dominant Narrative The main or most widely accepted story or viewpoint about a topic, interests or ideas in a dominant social group Spirituality A person's sense of connection to something bigger than themselves, such as nature, a higher power, or their own inner beliefs and values. A person's search for meaning and purpose in life, including how they connect with themselves, others, nature, the present moment, and what they consider meaningful or sacred Religion A set of beliefs, practices, and traditions that help people understand life, spirituality, and their connection to a higher power or something sacred Gender Expression How a person shows or expresses their gender through things like clothing, hairstyle, behavior, voice or appearance What is included with Telehealth? Telemedicine Remote Patient Monitoring Videoconferencing mHealth eConsults Patient education / Coaching Continuing Education for the provider Telemedicine Patient care / Consultation Patient Monitoring Mentoring Digital Imaging What is included in Telehealth Etiquite? Environment Performance Privacy Telehealth - Environment Visual- Provider appearance Room appearance Lighting Picture quality Auditory - Provider noises, background noise, audio quality Telehealth - Performance Provider appearance and communication Use of equipment Provider Preparation Telehealth - Privacy Privacy of sites Equipment privacy settings Consents Mastered (1) You've been getting these terms right! Select this one What is the main purpose of an interview? Gather pertinent information -Patient's illness and how well they are adapting to said illness Goal is to gather important information regarding patient's illness/condition and how they are coping with it Not studied (2) You haven't studied these terms yet! Select these 2 What is included in Chinese medicine? What happens if there is a disharmony between Yin & Yang?

Microbiology — Important Test Questions 1. What are microorganisms? Organisms too small to be seen with the unaided eye/ Human eye. 2. What are the major types of microbes? Bacteria, archaea, fungi, protozoa, algae, and viruses. 3. Are all microbes harmful? No. Most are helpful or harmless; only some are pathogenic. (Disease causing) 4. What are some important benefits of microbes? They decompose waste, produce oxygen, make foods and chemicals, and produce useful products such as insulin. (Medicine) Naming Microorganisms 5. What are the two parts of a scientific name? Genus and specific epithet. 6. How are scientific names written? The genus is capitalized, the specific epithet is lowercase, and both are italicized or underlined. 7. How is a scientific name abbreviated? The genus is shortened to its first letter. Example: Escherichia coli → E. coli. Bacteria -single cell 8. Are bacteria prokaryotic or eukaryotic? Prokaryotic. 9. Do bacteria have a nucleus? No. 10. What is found in bacterial cell walls? Peptidoglycan cell wall 11. How do bacteria reproduce? Binary fission. 12. How can bacteria obtain nutrition? From organic chemicals, inorganic chemicals, or photosynthesis. Archaea- single cell 13. Are archaea prokaryotic or eukaryotic? Prokaryotic. 14. Do archaea have peptidoglycan in their cell walls? No. 15. Where are many archaea found?c Extreme environments. 16. What are the three major groups of archaea mentioned? Methanogens, extreme halophiles, and extreme thermophiles. Fungi - can be mult 17. Are fungi prokaryotic or eukaryotic? Eukaryotic. 18. What is found in fungal cell walls? Chitin. 19. How do fungi obtain energy? They absorb organic chemicals. 20. What is the difference between yeast and molds? Yeasts are unicellular; molds are multicellular. 21. What are hyphae? Filaments that make up fungal mycelia. Protozoa- single cell 22. Are protozoa prokaryotic or eukaryotic? Eukaryotic. 23. How do protozoa obtain nutrients? They absorb or ingest organic chemicals. 24. How can protozoa move? Using pseudopods, cilia, or flagella. 25. Can protozoa be parasitic? Yes. Algae -can be mult 26. Are algae prokaryotic or eukaryotic? Eukaryotic. 27. What is found in algal cell walls? Cellulose. 28. How do algae obtain energy? Photosynthesis. 29. What do algae produce through photosynthesis? Oxygen and carbohydrates. Viruses- not living 30. Are viruses cellular? No. They are acellular. 31. What genetic material do viruses contain? DNA or RNA. 32. What surrounds the viral genetic material? A protein coat. 33. Can viruses reproduce on their own? No. They replicate only inside living host cells. Can only be seen in microsocp 34. What are viruses like outside a living host cell? They are inert. Classification 35. What are the three domains? Bacteria, Archaea, and Eukarya. 36. Who developed the three-domain system? Carl Woese. History of Microbiology 37. Who first observed microorganisms? Anton van Leeuwenhoek. 38. Who helped establish the idea that living things are made of cells? Robert Hooke. 39. What is cell theory? All living things are composed of cells. Pasteur & Fermentation 40. What did Pasteur show about fermentation? Microorganisms are responsible for fermentation. 41. What is fermentation? The microbial conversion of sugar to alcohol in the absence of air. 42. What is pasteurization? Using high heat for a short time to kill harmful bacteria in beverages. 43. Why is pasteurization important? It helps prevent microbial spoilage and kills harmful bacteria. Major Fields 47. What is bacteriology? Study of bacteria. 48. What is mycology? Study of fungi. 49. What is parasitology? Study of protozoa and parasitic worms. 50. What is immunology? Study of immunity. 51. What is virology? Study of viruses. Penicillin 44. Who discovered penicillin? Alexander Fleming. 45. What organism produced penicillin? The fungus Penicillium. 46. What type of microorganism did penicillin kill in Fleming's observation? Staphylococcus aureus bacteria. Genetics & Biotechnology 52. What is microbial genetics? Study of how microbes inherit traits. 53. What is molecular biology? How DNA directs protein synthesis. 54. What is genomics? Study of an organism's genes. 55. What is recombinant DNA? . DNA made from two different sources. 56. What is gene therapy? Replacing missing or defective genes in human cells Microbial Ecology & Biotechnology 57. What is microbial ecology? Study of the relationship between microorganisms and their environment. 58. What is bioremediation? Using microorganisms to clean up or detoxify pollutants. 59. How can bacteria help the environment? They can break down sewage and pollutants such as oil. 60. What is biotechnology? Using microorganisms for practical purposes, such as producing foods, chemicals, proteins, vaccines, and enzymes. Microbiota & Biofilms 61. What is microbiota? The microorganisms normally present in or on the body. 62. What is a biofilm? A mass of microorganisms attached to a solid surface. 63. Why are biofilms important medically? They can cause infections and are often resistant to antibiotics. 64. What does “pathogenic” mean? Disease-producing; capable of causing disease. 65. What is binary fission? A process in which one bacterial cell divides into two cells. 71. What did Anton van Leeuwenhoek call the microorganisms he observed? “Animalcules.” 74. Why is Bacillus thuringiensis useful in agriculture? It kills many harmful insects but is harmless to animals and plants, making it an alternative to chemical pesticides. All microorganisms that regularly populate the human body are referred to as the human microbiome

Week 2 ,, Yeast

Fungi & Yeasts

English 112: Discourse, Yeats, and Tennyson Review

Saliva and oral yeast

Yeast Identification and Mycology Lecture Notes

Lecture 15: Saliva and Oral Yeast

Vulvovaginal Candidiasis (Yeast Infection)

Fundamentals of Baking - Lean and Rich Yeasted Breads

Genomes & Yeast

Yeast (Exam 3)

Yeast Cells

Subcutaneous, Systemic, yeast like

bio Genetics is the study of heredity and how traits are passed from parents to offspring. Gregor Mendel is known as the “Father of Genetics.” Why did Mendel use pea plants? * Easy to grow * Short generation time * Many visible traits * Can self-pollinate or cross-pollinate * Produce many offspring Examples of traits studied: * Flower colour * Seed shape * Plant height ⸻ VOCABULARY Gene * A segment of DNA that controls a trait. Allele * Different forms of the same gene. Example: P = purple flowers p = white flowers Dominant Allele * Expressed whenever it is present. * Represented by a capital letter. Example: P = purple Recessive Allele * Only expressed when two copies are present. * Represented by a lowercase letter. Example: p = white Genotype * Genetic makeup of an organism. Examples: PP Pp pp Phenotype * Physical appearance of an organism. Examples: Purple flower White flower Homozygous * Two identical alleles. Examples: PP pp Heterozygous * Two different alleles. Example: Pp Pure Breeding * Homozygous for a trait. Gamete * Sex cell (sperm or egg). ⸻ MENDEL’S LAWS Law of Dominance * A dominant allele masks a recessive allele. Example: Pp = Purple flower Law of Segregation * Alleles separate during gamete formation. * Each gamete receives only one allele. Example: Parent = Pp Gametes: P p Law of Independent Assortment * Different genes assort independently during meiosis. ⸻ MONOHYBRID CROSSES A monohybrid cross studies one trait. Example: P = Purple p = White Cross: Pp × Pp Punnett Square INCOMPLETE DOMINANCE Neither allele completely dominates. Example: Snapdragons RR = Red WW = White RW = Pink Cross: RW × RW Genotype Ratio: 1 RR : 2 RW : 1 WW Phenotype Ratio: 1 Red : 2 Pink : 1 White CODOMINANCE Both alleles are expressed equally. Example: AB Blood Type Genotype: IAIB Phenotype: AB MULTIPLE ALLELES More than two alleles exist in a population. Example: ABO Blood Group Alleles: IA IB i BLOOD TYPES Type A Genotypes: IAIA or IAi Type B Genotypes: IBIB or IBi Type AB Genotype: IAIB Type O Genotype: ii Can Type A and Type B Parents Have a Type O Child? Yes. If: Father = IAi Mother = IBi Possible Blood Types: AB A B O CELL CYCLE Purpose: * Growth * Repair * Replacement of cells Stages: G1 S G2 Mitosis Cytokinesis INTERPHASE G1 Phase Cell grows and carries out normal functions. S Phase DNA replication occurs. G2 Phase Cell prepares for division. MITOSIS Purpose: Growth and repair. Produces: 2 genetically identical diploid cells. PROPHASE Events: * Chromosomes condense * Nuclear membrane disappears * Nucleolus disappears * Spindle fibres form METAPHASE Events: * Chromosomes line up at the equator ANAPHASE Events: * Sister chromatids separate TELOPHASE Events: * Nuclear membranes reform * Chromosomes uncoil CYTOKINESIS Division of the cytoplasm. Animal Cells: Cleavage furrow forms. Plant Cells: Cell plate forms. CHROMOSOME STRUCTURE Chromosome consists of: * Two sister chromatids * One centromere DIPLOID VS HAPLOID Diploid (2n) * Two sets of chromosomes * Human body cells * 46 chromosomes Haploid (n) * One set of chromosomes * Human gametes * 23 chromosomes HOMOLOGOUS CHROMOSOMES Chromosome pairs that: * Carry the same genes * One comes from the mother * One comes from the father Humans have 23 homologous pairs. MEIOSIS Purpose: Produce gametes. Produces: 4 genetically unique haploid cells. MEIOSIS I Separates homologous chromosomes. CROSSING OVER Occurs during Prophase I. Definition: Exchange of DNA between homologous chromosomes. Importance: Creates genetic variation. RANDOM ASSORTMENT Occurs during Metaphase I. Definition: Homologous pairs line up randomly. Importance: Creates unique chromosome combinations. MEIOSIS II Separates sister chromatids. MITOSIS VS MEIOSIS Mitosis * 2 cells produced * Diploid * Genetically identical * Growth and repair Meiosis * 4 cells produced * Haploid * Genetically different * Produces gametes NONDISJUNCTION Failure of chromosomes to separate properly during meiosis. Can result in extra or missing chromosomes. DOWN SYNDROME Cause: Extra chromosome 21. Chromosome Number: 47 Usually caused by nondisjunction during meiosis. DNA DNA = Deoxyribonucleic Acid Shape: Double Helix Function: Stores genetic information. NUCLEOTIDE Three Components: * Phosphate Group * Deoxyribose Sugar * Nitrogenous Base NITROGENOUS BASES Adenine (A) Thymine (T) Cytosine (C) Guanine (G) COMPLEMENTARY BASE PAIRING A pairs with T C pairs with G DNA REPLICATION Purpose: Make identical copies of DNA. Location: Nucleus Result: Two identical DNA molecules. TRANSCRIPTION Purpose: Create mRNA from DNA. Location: Nucleus DNA → mRNA Remember: RNA uses Uracil (U) instead of Thymine (T). TRANSLATION Purpose: Make proteins. Location: Ribosome mRNA is read and amino acids are joined together to form a protein. MUTATIONS A mutation is a change in DNA sequence. Types: * Deletion * Duplication * Inversion * Translocation DELETION DNA segment removed. DUPLICATION DNA segment repeated. INVERSION DNA segment reversed. TRANSLOCATION DNA segment moves to another chromosome. SEX-LINKED TRAITS Traits located on sex chromosomes. Most are located on the X chromosome. RED-GREEN COLOUR BLINDNESS Inheritance: X-linked recessive. XC = Normal Vision Xc = Colour Blind Male: XcY Colour blind boys inherit the allele from their mother because fathers pass a Y chromosome to their sons. TAY-SACHS DISEASE Cause: Missing enzyme that breaks down lipids in nerve cells. Inheritance: Autosomal recessive. Treatment: No cure currently available. SICKLE CELL ANEMIA Cause: Mutation in hemoglobin gene. Effects: * Sickle-shaped red blood cells * Reduced oxygen transport * Blocked blood vessels Inheritance: Autosomal recessive. HUNTINGTON’S DISEASE Cause: Dominant mutation. Effects: * Nervous system degeneration * Loss of motor control * Cognitive decline Inheritance: Autosomal dominant. KARYOTYPE A photograph of chromosomes arranged in pairs. Used to: * Determine sex * Detect chromosome abnormalities * Diagnose genetic disorders PEDIGREE A family tree used to track inheritance patterns. Symbols: Square = Male Circle = Female Shaded = Has trait CLONING Producing genetically identical organisms. Uses: * Research * Agriculture * Medicine * Conservation GENETIC COUNSELLING Provides information about: * Inherited disorders * Family risk * Testing options AMNIOCENTESIS Prenatal test in which amniotic fluid is sampled and fetal cells are analyzed. Can detect: * Genetic disorders * Chromosomal disorders GMOs Genetically Modified Organisms. Definition: Organisms whose DNA has been altered through biotechnology. Advantages: * Increased crop yield * Disease resistance * Pest resistance Disadvantages: * Ethical concerns * Environmental concerns DNA REPLICATION → TRANSCRIPTION → TRANSLATION DNA (Nucleus) ↓ Replication DNA Copy DNA ↓ Transcription mRNA mRNA ↓ Translation Protein Final Product: Protein RESPIRATORY SYSTEM Function: * Brings oxygen into the body * Removes carbon dioxide * Works with the circulatory system to supply cells with oxygen Why do organisms require oxygen and produce carbon dioxide? Oxygen is required for cellular respiration. Cellular Respiration: Glucose + Oxygen → Energy (ATP) + Carbon Dioxide + Water Cells use oxygen to release energy from food. Carbon dioxide is produced as a waste product and must be removed. ⸻ PATHWAY OF AIR Nasal Cavity ↓ Pharynx ↓ Larynx ↓ Trachea ↓ Bronchi ↓ Bronchioles ↓ Alveoli ⸻ NASAL CAVITY Functions: * Warms air * Moistens air * Filters air Nasal Hairs: * Trap large particles Mucus: * Traps dust and microorganisms Blood Capillaries: * Warm incoming air ⸻ PHARYNX Common passageway for: * Air * Food Also called the throat. ⸻ UVULA Functions: * Prevents food from entering nasal cavity * Helps with speech ⸻ EPIGLOTTIS Functions: * Covers trachea during swallowing * Prevents choking ⸻ LARYNX Also called the voice box. Contains vocal cords. ⸻ TRACHEA Also called the windpipe. Contains cartilage rings that prevent collapse. Lined with: * Cilia * Mucus ⸻ CILIA Tiny hair-like structures. Function: * Sweep mucus upward toward throat ⸻ BRONCHI Two branches of the trachea leading to lungs. Right Bronchus → Right Lung Left Bronchus → Left Lung ⸻ BRONCHIOLES Smaller branches inside lungs. Lead to alveoli. ⸻ ALVEOLI Tiny air sacs. Site of gas exchange. Adaptations: * Thin walls * Moist surface * Large surface area * Rich blood supply Gas Exchange: Oxygen moves: Alveoli → Blood Carbon Dioxide moves: Blood → Alveoli By diffusion. ⸻ BREATHING MECHANICS Two main muscles: 1. Diaphragm 2. Intercostal Muscles ⸻ INHALATION (INSPIRATION) Diaphragm: * Contracts * Moves downward Intercostal Muscles: * Contract * Lift ribs upward Result: * Chest cavity volume increases * Pressure decreases * Air enters lungs ⸻ EXHALATION (EXPIRATION) Diaphragm: * Relaxes * Moves upward Intercostal Muscles: * Relax Result: * Chest cavity volume decreases * Pressure increases * Air leaves lungs ⸻ MEDULLA OBLONGATA Located in the brainstem. Function: * Controls breathing rate Responds to: * Carbon dioxide levels More CO₂: * Faster breathing Less CO₂: * Slower breathing ⸻ LUNG VOLUMES Tidal Volume * Normal amount of air breathed in and out Inspiratory Reserve Volume * Extra air inhaled after normal breath Expiratory Reserve Volume * Extra air exhaled after normal breath Residual Volume * Air remaining in lungs after maximum exhalation Vital Capacity * Maximum amount of air exhaled after deepest breath Total Lung Capacity * Total amount of air lungs can hold ⸻ CIRCULATORY SYSTEM Functions: * Transport oxygen * Transport nutrients * Remove wastes * Maintain homeostasis * Transport hormones Humans have a CLOSED circulatory system. Blood remains inside vessels. ⸻ BLOOD VESSELS ARTERIES Function: * Carry blood away from heart Characteristics: * Thick walls * High pressure * Small lumen * No valves Usually oxygen-rich Exception: Pulmonary artery ⸻ VEINS Function: * Carry blood toward heart Characteristics: * Thin walls * Low pressure * Large lumen * Valves present Usually oxygen-poor Exception: Pulmonary vein ⸻ CAPILLARIES Smallest blood vessels. Functions: * Gas exchange * Nutrient exchange * Waste exchange Walls are one cell thick. ⸻ HEART STRUCTURE Blood Flow: Body ↓ Vena Cava ↓ Right Atrium ↓ Right Ventricle ↓ Pulmonary Artery ↓ Lungs ↓ Pulmonary Vein ↓ Left Atrium ↓ Left Ventricle ↓ Aorta ↓ Body ⸻ HEART CHAMBERS Right Atrium * Receives deoxygenated blood Right Ventricle * Pumps blood to lungs Left Atrium * Receives oxygenated blood Left Ventricle * Pumps blood to body ⸻ SEPTUM Wall separating left and right sides of heart. Prevents mixing of blood. ⸻ HEART VALVES Function: * Prevent backflow of blood Types: Atrioventricular (AV) Valves Pulmonary Semilunar Valve Aortic Semilunar Valve ⸻ SA NODE Sinoatrial Node Known as: * Natural pacemaker Initiates heartbeat. ⸻ AV NODE Atrioventricular Node Receives signal from SA node. Delays impulse slightly. Allows ventricles to fill before contraction. ⸻ BLOOD Components: 1. Plasma 2. Red Blood Cells 3. White Blood Cells 4. Platelets ⸻ PLASMA Liquid component of blood. Functions: * Transport nutrients * Transport hormones * Transport wastes ⸻ RED BLOOD CELLS (ERYTHROCYTES) Function: * Carry oxygen Contain: * Hemoglobin ⸻ HEMOGLOBIN Protein in red blood cells. Function: * Binds oxygen Allows oxygen transport. ⸻ WHITE BLOOD CELLS (LEUKOCYTES) Function: * Fight infection * Defend body Part of immune system. ⸻ PLATELETS Function: * Blood clotting Prevent blood loss. ⸻ BLOOD PRESSURE Force of blood against artery walls. Measured using: Sphygmomanometer Example: 120/80 120 = Systolic Pressure 80 = Diastolic Pressure ⸻ SYSTOLIC PRESSURE Pressure when heart contracts. ⸻ DIASTOLIC PRESSURE Pressure when heart relaxes. ⸻ HYPERTENSION High blood pressure. Can increase risk of: * Stroke * Heart attack * Kidney disease ⸻ STROKE VOLUME Amount of blood pumped per heartbeat. ⸻ CARDIAC OUTPUT Amount of blood pumped per minute. Formula: Cardiac Output = Heart Rate × Stroke Volume ⸻ ECG Electrocardiogram Measures electrical activity of heart. Used to detect: * Irregular heartbeat * Heart damage ⸻ PULMONARY CIRCULATION Heart → Lungs → Heart Purpose: * Oxygenate blood ⸻ SYSTEMIC CIRCULATION Heart → Body → Heart Purpose: * Deliver oxygen to tissues ⸻ HOMEOSTASIS DURING EXERCISE Body responds by: * Increasing heart rate * Increasing breathing rate * Increasing cardiac output * Redirecting blood to muscles * Sweating to cool body Purpose: Maintain stable internal conditions. ⸻ DIGESTIVE SYSTEM Functions: * Break down food * Absorb nutrients * Eliminate waste ⸻ DIGESTIVE TRACT Mouth ↓ Pharynx ↓ Esophagus ↓ Stomach ↓ Small Intestine ↓ Large Intestine ↓ Rectum ↓ Anus ⸻ MECHANICAL DIGESTION Physical breakdown of food. Examples: * Chewing * Churning ⸻ CHEMICAL DIGESTION Chemical breakdown of food using enzymes. Examples: * Amylase * Pepsin ⸻ SALIVA Functions: 1. Moistens food 2. Contains amylase Amylase begins carbohydrate digestion. ⸻ TONGUE Functions: 1. Forms bolus 2. Pushes food for swallowing ⸻ ESOPHAGUS Moves food to stomach. Uses: Peristalsis ⸻ PERISTALSIS Wave-like muscular contractions. Move food through digestive tract. ⸻ STOMACH Functions: * Stores food * Mixes food * Begins protein digestion Produces: * HCl * Pepsin * Mucus ⸻ HCl Hydrochloric Acid Functions: * Kills bacteria * Activates pepsin ⸻ PEPSIN Function: * Digests proteins ⸻ MUCUS Function: * Protects stomach lining ⸻ CHYME Semi-liquid food mixture leaving stomach. ⸻ HEARTBURN Cause: Stomach acid enters esophagus. Usually caused by weakened cardiac sphincter. ⸻ SMALL INTESTINE Main site of: * Digestion * Absorption Adaptations: * Long length * Folds * Villi * Microvilli Large surface area increases absorption. ⸻ DUODENUM First section. Functions: * Receives bile * Receives pancreatic enzymes * Most chemical digestion ⸻ JEJUNUM Main nutrient absorption. ⸻ ILEUM Final nutrient absorption. ⸻ VILLI Finger-like projections. Function: Increase surface area. ⸻ LIVER Functions: * Produces bile * Processes nutrients * Detoxifies blood ⸻ GALL BLADDER Functions: * Stores bile * Releases bile into small intestine ⸻ PANCREAS Functions: * Produces digestive enzymes * Produces bicarbonate ⸻ BILE Function: Emulsifies fats. Breaks large fat droplets into smaller droplets. Makes fat digestion easier. ⸻ DIGESTION OF CARBOHYDRATES Mouth: * Amylase begins digestion Small Intestine: * Pancreatic amylase continues digestion End Product: Glucose ⸻ DIGESTION OF PROTEINS Stomach: * Pepsin begins digestion Small Intestine: * Trypsin continues digestion End Product: Amino Acids ⸻ DIGESTION OF LIPIDS Small Intestine: * Bile emulsifies fats * Lipase digests fats End Product: Fatty Acids + Glycerol ⸻ EVOLUTION Evolution: Change in populations over time. Individuals do NOT evolve. Populations evolve. ⸻ DARWIN Proposed: Natural Selection Book: On the Origin of Species ⸻ WALLACE Independently developed theory of natural selection. ⸻ LAMARCK Proposed: Inheritance of acquired characteristics Example: Giraffes stretch necks and pass longer necks to offspring. This theory is incorrect. ⸻ NATURAL SELECTION Requirements: 1. Variation 2. Overproduction 3. Competition 4. Differential Survival 5. Reproduction Result: Adaptation ⸻ ADAPTATION Inherited characteristic that increases survival and reproduction. ⸻ SELECTIVE ADVANTAGE A characteristic that improves survival or reproduction. Example: Antibiotic resistance ⸻ SELECTIVE PRESSURE Environmental factor that influences survival. Examples: * Predators * Disease * Climate * Competition ⸻ VARIATION Differences among individuals in a population. Sources: * Mutation * Crossing Over * Random Assortment ⸻ MUTATION Ultimate source of new alleles. Creates genetic variation. ⸻ FOSSIL Preserved remains or traces of organisms. ⸻ FOSSIL RECORD Collection of fossils showing evolutionary history. Provides evidence for evolution. ⸻ RADIOACTIVE DATING Uses radioactive isotopes to determine fossil age. ⸻ UNIFORMITARIANISM Proposed by Lyell. Earth changes gradually over long periods of time. ⸻ CATASTROPHISM Proposed by Cuvier. Earth shaped by sudden catastrophic events. ⸻ BIOGEOGRAPHY Study of species distribution around Earth. Provides evidence for evolution. ⸻ EMBRYOLOGY Study of embryos. Similar embryos suggest common ancestry. ⸻ HOMOLOGOUS STRUCTURES Same evolutionary origin. Different functions. Example: Human arm Whale flipper Bat wing Evidence of common ancestry. ⸻ ANALOGOUS STRUCTURES Different origins. Same function. Example: Bird wing Insect wing Not evidence of close ancestry. ⸻ VESTIGIAL STRUCTURES Structures with little or no function. Examples: * Human appendix * Whale pelvis Evidence of evolution. ⸻ MIMICRY One species resembles another. Example: Syrphid fly resembles wasp. Provides protection. ⸻ ARTIFICIAL SELECTION Humans select traits. Examples: * Dog breeding * Crop breeding ⸻ DIRECTIONAL SELECTION One extreme phenotype favored. Graph shifts in one direction. ⸻ STABILIZING SELECTION Average phenotype favored. Extremes selected against. ⸻ DISRUPTIVE SELECTION Both extremes favored. Middle selected against. ⸻ GENETIC DRIFT Random change in allele frequencies. Most significant in small populations. ⸻ FOUNDER EFFECT Small group starts new population. Different allele frequencies from original population. ⸻ BOTTLENECK EFFECT Population drastically reduced. Loss of genetic variation. ⸻ GENE FLOW Movement of alleles between populations. Occurs through migration. ⸻ NON-RANDOM MATING Individuals choose specific mates. Can reduce variation. ⸻ SPECIES A group of organisms that can interbreed in nature and produce fertile offspring. ⸻ SPECIATION Formation of new species. ⸻ ALLOPATRIC SPECIATION Requires: Geographic isolation Example: Mountain separates populations. ⸻ SYMPATRIC SPECIATION Occurs without geographic isolation. ⸻ PRE-ZYGOTIC ISOLATION Prevents fertilization. Examples: * Different mating seasons * Different mating songs * Different habitats ⸻ POST-ZYGOTIC ISOLATION Occurs after fertilization. Example: Sterile hybrids Example: Mule DIVERSITY Prokaryotes vs Eukaryotes PROKARYOTES * No nucleus * No membrane-bound organelles * Circular DNA * Smaller * Examples: Eubacteria, Archaebacteria EUKARYOTES * Nucleus present * Membrane-bound organelles * Linear chromosomes * Larger * Examples: Protists, Fungi, Plants, Animals Three Differences: 1. Nucleus vs no nucleus 2. Organelles vs no organelles 3. Larger vs smaller ⸻ Taxonomy Kingdom Phylum Class Order Family Genus Species Mnemonic: King Philip Came Over For Good Soup ⸻ Binomial Nomenclature Genus + Species Example: Homo sapiens Rules: * Genus capitalized * Species lowercase * Italicized Purpose: * Universal naming system * Avoids confusion * Shows relationships ⸻ Dichotomous Key Used to identify organisms using paired choices. Example: 1a Has wings → Step 2 1b No wings → Step 3 ⸻ Six Kingdoms 1. Archaebacteria 2. Eubacteria 3. Protista 4. Fungi 5. Plantae 6. Animalia ⸻ VIRUSES Virus Structure: * DNA or RNA * Capsid * Attachment proteins * Sometimes envelope Why Viruses Are Not Living: * Not made of cells * Cannot reproduce independently * No metabolism * Need host cell ⸻ DNA Virus vs RNA Virus DNA Virus: * Contains DNA * More stable RNA Virus: * Contains RNA * Mutates faster ⸻ Lytic Cycle Attachment ↓ Penetration ↓ Replication ↓ Assembly ↓ Lysis Host cell bursts. ⸻ Lysogenic Cycle Attachment ↓ Penetration ↓ Integration into host DNA ↓ Host reproduces ↓ Virus DNA copied Cell survives initially. ⸻ ARCHAEBACTERIA Characteristics: * Prokaryotic * Unicellular * Extreme environments Three Groups: Methanogens * Produce methane Halophiles * Salt-loving Thermoacidophiles * Hot acidic environments ⸻ EUBACTERIA Characteristics: * Prokaryotic * Peptidoglycan cell wall * Binary fission Examples: * E. coli * Streptococcus ⸻ Binary Fission DNA Replication ↓ Cell Growth ↓ Cell Division ↓ Two Identical Cells ⸻ Conjugation DNA transfer through pilus. Importance: * Genetic variation * Antibiotic resistance ⸻ Antibiotic Resistance Mutation ↓ Antibiotic kills susceptible bacteria ↓ Resistant bacteria survive ↓ Resistant bacteria reproduce Natural Selection ⸻ PROTISTS Characteristics: * Eukaryotic * Mostly unicellular * Aquatic Three Groups: Animal-like * Amoeba * Paramecium Plant-like * Algae * Euglena Fungus-like * Slime molds ⸻ Amoeba * Uses pseudopods * Phagocytosis ⸻ Algae * Photosynthetic * Oxygen producer ⸻ Euglena * Chloroplasts * Flagellum * Photosynthesis * Can also feed heterotrophically ⸻ Malaria Cause: Plasmodium Kingdom: Protista ⸻ FUNGI Characteristics: * Eukaryotic * Heterotrophic * Chitin cell walls * Reproduce with spores Examples: * Mushrooms * Mold * Yeast ⸻ External Digestion Release enzymes ↓ Digest food outside body ↓ Absorb nutrients ⸻ Fungi vs Plants FUNGI * Heterotrophic * Chitin * No chloroplasts PLANTS * Autotrophic * Cellulose * Chloroplasts ⸻ PLANTS Biodiversity vs Monoculture BIODIVERSITY * Many species * Stable ecosystem * Disease resistance MONOCULTURE * One crop species * Low diversity * Disease risk ⸻ Bryophytes Definition: Nonvascular plants Examples: * Mosses * Liverworts Characteristics: * No xylem * No phloem * Need water for reproduction ⸻ Vascular Plants Contain: * Xylem * Phloem ⸻ Xylem Function: Water and minerals Direction: Roots → Leaves ⸻ Phloem Function: Sugars Direction: Throughout plant ⸻ Alternation of Generations Sporophyte (2n) ↓ meiosis Spores (n) ↓ Gametophyte (n) ↓ Gametes ↓ fertilization Zygote (2n) ↓ Sporophyte ⸻ Moss Life Cycle Spores ↓ Gametophyte ↓ Egg + Sperm ↓ Zygote ↓ Sporophyte ↓ Capsule ↓ Spores Know: * Capsule * Sporophyte * Gametophyte * Spores ⸻ Fern Life Cycle Fern ↓ Sori ↓ Spores ↓ Prothallus ↓ Gametes ↓ Fertilization ↓ Young Fern Know: * Frond * Sori * Sporangia * Prothallus ⸻ Gymnosperms Characteristics: * Naked seeds * Cones * Wind pollination * Evergreen Examples: * Pine * Spruce * Fir ⸻ Angiosperms Characteristics: * Flowers * Fruit * Seeds enclosed Examples: * Apple tree * Rose * Maple ⸻ Flower Structure Anther * Produces pollen Pollen Grain * Male gamete Stigma * Receives pollen Style * Connects stigma and ovary Ovary * Contains ovules Ovule * Female gamete Petals * Attract pollinators ⸻ Plant Tissues Meristematic * Growth Dermal * Protection Ground * Photosynthesis * Storage Vascular * Transport ⸻ Leaf Structure Blade * Main leaf surface Petiole * Connects leaf to stem Cuticle * Reduces water loss Palisade Mesophyll * Photosynthesis Spongy Mesophyll * Gas exchange Veins * Xylem + Phloem ⸻ Stomata Openings in leaves. Functions: * Gas exchange * Water loss ⸻ Guard Cells Control opening and closing of stomata. ⸻ Transpiration Water loss from leaves. Functions: * Pulls water upward * Cools plant * Moves minerals ⸻ Simple vs Compound Leaves Simple: * One blade Compound: * Multiple leaflets ⸻ Monocots vs Dicots MONOCOTS * 1 cotyledon * Parallel veins * Fibrous roots * Flower parts in 3s Examples: Corn Grass DICOTS * 2 cotyledons * Net veins * Taproot * Flower parts in 4s or 5s Examples: Bean Maple ⸻ Seeds Contain: * Embryo * Stored food * Seed coat Functions: * Protection * Survival * Dispersal ⸻ Seed Dispersal Wind * Dandelion Water * Coconut Animals * Burrs Explosive * Touch-me-not ⸻ Fruit vs Vegetable Fruit: * Comes from ovary * Contains seeds Examples: Tomato Apple Pepper Vegetable: * Root, stem, leaf, or flower Examples: Carrot Celery Broccoli ⸻ Factors Affecting Plant Growth 1. Light 2. Water 3. Carbon dioxide 4. Temperature 5. Soil nutrients 6. Oxygen 7. Soil pH 8. Space 9. Pollinators 10. Disease and pests

EMPA ENGLISH JUNIOR YEAT