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# Glandular Tissue & Lymphatic System ## Chapter 7: Glandular Tissue ### Summary This chapter details the endocrine and exocrine glands of the head and neck, their locations, secretions, functions, innervations, lymphatic drainage, and blood supply. Understanding these glands is crucial for dental professionals to identify disease processes. ### Key Information #### Gland Types - **Exocrine Gland:** Has a duct to empty secretions directly to the site of use (e.g., salivary glands). - **Endocrine Gland:** Ductless, secretes directly into the vascular system (e.g., thyroid gland). - Motor nerves regulate secretion flow; sensory nerves are also present. #### Lacrimal Glands - **Type:** Paired almond-shaped exocrine glands. - **Secretions:** Lacrimal fluid (tears) for lubricating the conjunctiva and eyeball. - **Location:** Lacrimal fossa of the frontal bone, just inside the lateral part of the supraorbital rim. - **Ducts:** Lacrimal ducts collect tears, which then pass to the lacrimal punctum, lacrimal sac, nasolacrimal duct, and finally drain into the inferior nasal meatus. - **Innervation:** Parasympathetic fibers from the greater petrosal nerve (branch of facial nerve), synapsing at the pterygopalatine ganglion. Postganglionic fibers reach the gland via maxillary branches of the trigeminal nerve and lacrimal nerve. - **Lymphatic Drainage:** Superficial parotid lymph nodes. - **Blood Supply:** Lacrimal artery (branch of ophthalmic artery); venous return via superior ophthalmic vein. - **Pathology:** Dry eye syndrome (DES) or keratoconjunctivitis sicca (KCS) due to reduced lacrimal fluid production. #### Salivary Glands - **Function:** Produce saliva to lubricate and cleanse the oral cavity, aid digestion, and contribute to immune defense. - **Control:** Autonomic nervous system. - **Types:** Major (large, encapsulated, named ducts) and Minor (smaller, more numerous, unencapsulated, shorter unnamed ducts). Both are exocrine. ##### Major Salivary Glands 1. **Parotid Salivary Gland** - **Type:** Largest encapsulated major salivary gland. - **Secretions:** Serous type only (25% of total salivary volume). - **Location:** Parotid space, posterior to mandibular ramus, anterior and inferior to each ear, overlying the masseter muscle. - **Duct:** Parotid duct (Stensen duct) opens into the oral cavity opposite the maxillary second molar. - **Innervation:** Efferent (parasympathetic) fibers from the otic ganglion of the glossopharyngeal nerve (ninth cranial nerve) via the lesser petrosal nerve. Postganglionic fibers carried by the auriculotemporal nerve (mandibular division of trigeminal nerve). Facial nerve passes through but does not innervate. - **Lymphatic Drainage:** Deep parotid lymph nodes. - **Blood Supply:** Transverse facial artery (branch of external carotid artery); venous return via retromandibular vein. - **Pathology:** Enlargement and tenderness with mumps (parotitis), most salivary gland cancers involve the parotid. 2. **Submandibular Salivary Gland** - **Type:** Second largest encapsulated major salivary gland. - **Secretions:** Mixed serous and mucous (60-65% of total salivary volume). - **Location:** Submandibular fossa in the submandibular space, inferior and posterior to the body of the mandible. - **Duct:** Submandibular duct (Wharton duct) opens at the sublingual caruncle in the floor of the mouth. - **Innervation:** Efferent (parasympathetic) fibers of the chorda tympani nerve (facial nerve) synapsing in the submandibular ganglion. Postganglionic fibers delivered by the lingual nerve (mandibular division of trigeminal nerve). - **Lymphatic Drainage:** Submandibular lymph nodes. - **Blood Supply:** Glandular branches of the facial artery; venous return mainly by the facial vein. - **Pathology:** Most common site for salivary stones (sialoliths). 3. **Sublingual Salivary Gland** - **Type:** Smallest, most diffuse, and only unencapsulated major salivary gland. - **Secretions:** Mixed, predominately mucous (10% of total salivary volume). - **Location:** Sublingual fossa in the sublingual space at the floor of the mouth, deep to the sublingual fold, anterior to the submandibular gland. - **Ducts:** Ducts of Rivinus (8-20 small ducts) open along the sublingual fold; sometimes form a larger Bartholin duct opening at the sublingual caruncle. - **Innervation:** Same as submandibular gland: efferent (parasympathetic) fibers of the chorda tympani nerve (facial nerve) and submandibular ganglion. Postganglionic fibers delivered by the lingual nerve (mandibular division of trigeminal nerve). - **Lymphatic Drainage:** Submandibular lymph nodes. - **Blood Supply:** Sublingual artery (off lingual artery); parallel venous return. ##### Minor Salivary Glands - **Type:** More numerous than major glands, unencapsulated. - **Secretions:** Mainly mucous, except von Ebner glands (serous only). - **Location:** Scattered throughout oral mucosa (buccal, labial, lingual, soft palate, posterior hard palate, floor of mouth). Von Ebner glands associated with circumvallate lingual papillae. - **Ducts:** Single, short ducts directly into the oral cavity. - **Innervation:** Preganglionic from facial nerve, postganglionic from various branches of the trigeminal nerve. - **Lymphatic Drainage & Blood Supply:** Various nodes and arteries depending on location. - **Pathology:** Mucocele (blockage of duct from trauma). #### Thyroid Gland - **Type:** Largest endocrine gland (ductless). - **Secretions:** Thyroxine (hormone) directly into the vascular system to stimulate metabolic rate. - **Location:** Anterolateral regions of the neck, inferior to the thyroid cartilage, at the junction of the larynx and trachea. - **Innervation:** Sympathetic nerves through cervical ganglia (do not control secretion; pituitary gland regulates hormone release). - **Lymphatic Drainage:** Superior deep cervical lymph nodes. - **Blood Supply:** Superior and inferior thyroid arteries (possibly thyroid ima artery); venous return via superior, middle, and inferior thyroid veins. - **Pathology:** Goiter (enlarged thyroid gland), loss of mobility indicating neoplastic growth. #### Parathyroid Glands - **Type:** Usually four small endocrine glands (ductless). - **Secretions:** Parathyroid hormone directly into the vascular system to regulate calcium and phosphorus levels. - **Location:** Adjacent to or within the thyroid gland on its posterior surface (not visible or palpable). - **Innervation:** Same as thyroid gland: sympathetic nerves through cervical ganglia. - **Lymphatic Drainage:** Superior deep cervical lymph nodes. - **Blood Supply:** Primarily inferior thyroid arteries (possibly anastomotic branch between inferior and superior thyroid arteries); venous return via superior, middle, and inferior thyroid veins. #### Thymus Gland - **Type:** Endocrine gland (ductless) and part of the immune system. - **Function:** T-cell lymphocytes mature here. Grows until puberty, then shrinks (involution). - **Location:** Thorax and anterior region of the base of the neck, inferior to the thyroid gland, superficial and lateral to the trachea, deep to the sternum. - **Innervation:** Branches of the vagus nerve (tenth cranial nerve) and cervical spinal nerves. - **Lymphatic Drainage:** Lymphatic system begins within the gland and terminates in the internal jugular vein (no afferent vessels). - **Blood Supply:** Inferior thyroid and internal thoracic arteries; venous return via veins in the posterior surface directly into brachiocephalic veins. - **Pathology:** Thymic rests (ectopic accessory thymic tissue). ## Chapter 10: Lymphatic System ### Summary This chapter covers the lymphatic system, its components (vessels, nodes, ducts, tonsils), and its role in fighting disease. It details the location, drainage patterns, and clinical significance of lymph nodes and tonsils in the head and neck. ### Key Information #### Lymphatic System Overview - **Components:** Vessels, nodes, ducts, tonsils. - **Function:** Part of the immune system, fights infection and cancer, drains tissue fluid (lymph). - **Lymphatic Vessels:** Parallel venous blood vessels, have one-way valves, drain lymph. - **Lymph Nodes:** Bean-shaped bodies in clusters, filter toxic products from lymph, contain lymphocytes (white blood cells), involved in lymphocyte production. - **Afferent vessels:** Lymph flows into the node. - **Efferent vessel:** Lymph flows out of the node at the hilus. - **Primary node (regional/master node):** First node lymph drains into from a particular region. - **Secondary node (central node):** Node that primary nodes drain into. - **Lymphatic Ducts:** Larger vessels formed by converging lymphatic vessels. - **Right lymphatic duct:** Drains right side of head and neck, right arm, and thorax into the junction of the right subclavian and right internal jugular veins. - **Thoracic duct:** Drains left side of head and neck, left arm, thorax, and entire lower half of the body into the junction of the left subclavian and left internal jugular veins. - **Tonsils:** Masses of lymphoid tissue near airway and food passages, contain lymphocytes, drain into superior deep cervical lymph nodes. #### Lymph Nodes of the Head ##### Superficial Lymph Nodes of the Head - **Occipital Lymph Nodes:** - **Location:** Posterior base of the head (occipital region). - **Drainage:** Scalp in the occipital region. - **Empties into:** Deep cervical nodes. - **Posterior Auricular, Anterior Auricular, and Superficial Parotid Lymph Nodes:** - **Posterior Auricular:** Posterior to each auricle and external acoustic meatus. - **Anterior Auricular:** Immediately anterior to each tragus. - **Superficial Parotid:** Superficial to each parotid salivary gland. - **Drainage:** External ear, lacrimal gland, adjacent scalp and face. - **Empties into:** Deep cervical nodes. - **Facial Lymph Nodes:** - **Location:** Along the facial vein. - **Subgroups:** Malar (infraorbital), Nasolabial (along nasolabial sulcus), Buccal (around labial commissure), Mandibular (superior to mandible, anterior to masseter). - **Drainage:** Skin and mucous membranes where located, drain superior to inferior. - **Empties into:** Deep cervical nodes via submandibular nodes. ##### Deep Lymph Nodes of the Head - Cannot be palpated extraorally. - **Deep Parotid Lymph Nodes:** - **Location:** Deep within the parotid salivary gland. - **Drainage:** Middle ear, auditory tube, parotid salivary gland. - **Empties into:** Deep cervical nodes. - **Retropharyngeal Lymph Nodes:** - **Location:** Near deep parotid nodes, at the level of the atlas. - **Drainage:** Posterior palate, pharynx, paranasal sinuses, nasal cavity. - **Empties into:** Deep cervical nodes. #### Cervical Lymph Nodes - Paired, unilaterally drain tissues (except submental nodes, which drain bilaterally). - Categorized into superficial and deep. - Medical community uses a 7-level classification (Node Levels I-VII). ##### Superficial Cervical Lymph Nodes - **Submental Lymph Nodes (Node Level I, Sublevel a):** - **Location:** Inferior to the chin, within the submental fascial space and submental triangle. - **Drainage:** Lower lip, chin, floor of mouth, apex of tongue, mandibular incisors with periodontium and gingiva. - **Empties into:** Submandibular nodes or directly into deep cervical nodes. - **Clinical Significance:** Risk for spread of cancers from floor of mouth, apex of tongue, mandibular anterior alveolar process, lower lip. - **Submandibular Lymph Nodes (Node Level I, Sublevel b):** - **Location:** Inferior border of the mandibular ramus, superficial to the submandibular salivary gland. - **Drainage:** Cheeks, upper lip, body of tongue, anterior hard palate, most teeth (except mandibular incisors and maxillary third molars), sublingual and submandibular salivary glands. Secondary nodes for submental and facial regions. - **Empties into:** Deep cervical nodes. - **Clinical Significance:** Risk for spread of cancers from oral cavity, anterior nasal cavity, midface structures, submandibular salivary gland. - **External Jugular Lymph Nodes (Superficial Cervical Nodes):** - **Location:** Along the external jugular vein, superficial to the SCM muscle. - **Drainage:** Secondary nodes for occipital, posterior auricular, anterior auricular, and superficial parotid nodes. - **Empties into:** Deep cervical nodes. - **Anterior Jugular Lymph Nodes (Anterior Cervical Nodes):** - **Location:** Along the anterior jugular vein, anterior to larynx, trachea, superficial to SCM muscle. - **Drainage:** Infrahyoid region of the neck. - **Empties into:** Deep cervical nodes. ##### Deep Cervical Lymph Nodes - **Location:** Along the internal jugular vein, deep to the SCM muscle, from skull base to root of neck. - Divided into superior and inferior based on omohyoid muscle crossing internal jugular vein. - **Node Level II (Superior one-third):** - **Location:** From digastric muscle superiorly to hyoid bone/carotid bifurcation inferiorly. - **Drainage:** Oral cavity, nasal cavity, nasopharynx, oropharynx, laryngopharynx, larynx, parotid salivary gland. - **Jugulodigastric lymph node (tonsillar node):** Prominent node in this group, drains palatine tonsils. - **Node Level III (Middle one-third):** - **Location:** From hyoid bone/carotid bifurcation superiorly to cricothyroid notch/cricoid cartilage/omohyoid muscle inferiorly. - **Drainage:** Oral cavity, nasopharynx, oropharynx, laryngopharynx, larynx. - **Node Level IV (Inferior one-third):** - **Location:** From omohyoid muscle superiorly to clavicle inferiorly. - **Drainage:** Laryngopharynx, esophagus, larynx. - **Node Level V (Posterior cervical triangle):** - **Location:** From skull base at posterior SCM border to clavicle. - **Drainage:** Nasopharynx, oropharynx (Sublevel a), thyroid gland (Sublevel b). - **Node Level VI (Anterior compartment):** - **Location:** Inferior to hyoid bone, between medial margins of common carotid arteries. - **Drainage:** Thyroid gland, specific parts of larynx, esophagus. - **Superior Deep Cervical Lymph Nodes:** - **Location:** Deep to SCM muscle, superior to omohyoid muscle crossing internal jugular vein. - **Drainage:** Posterior nasal cavity, posterior hard palate, soft palate, base of tongue (bilateral drainage), maxillary third molars, TMJ, esophagus, trachea, thyroid gland. Secondary nodes for most other head and neck nodes. - **Empties into:** Inferior deep cervical nodes or directly into jugular trunk. - **Inferior Deep Cervical Lymph Nodes:** - **Location:** Deep to SCM muscle, inferior to omohyoid muscle crossing internal jugular vein, extending into supraclavicular fossa. - **Drainage:** Posterior scalp and neck, superficial pectoral region, part of arm. Secondary nodes for superficial head nodes and superior deep cervical nodes. - **Jugulo-omohyoid lymph node:** Drains tongue and submental triangle; enlarged node can indicate tongue carcinoma. - **Empties into:** Jugular trunk (right) or thoracic duct (left). - **Clinical Significance:** Communicates with axillary lymph nodes, high risk for spread of breast cancer. - **Accessory Lymph Nodes:** - **Location:** Along the eleventh cranial (accessory) nerve. - **Drainage:** Scalp and neck regions. - **Empties into:** Supraclavicular nodes. - **Supraclavicular Lymph Nodes:** - **Location:** Superiorly along the clavicle. - **Drainage:** Lateral cervical triangles. - **Empties into:** Jugular trunks or directly into right lymphatic duct/thoracic duct. - **Clinical Significance:** Final endpoint of lymphatic drainage from entire body, high risk for spread of cancers from lungs, esophagus, stomach. #### Tonsils - **Palatine Tonsils:** - **Location:** Oral cavity, between anterior and posterior faucial pillars. - **Lingual Tonsil:** - **Location:** Dorsal surface of the base of the tongue. - **Pharyngeal Tonsil (Adenoids):** - **Location:** Midline of the posterior wall/roof of the nasopharynx. - **Tubal Tonsil:** - **Location:** Nasopharynx, posterior to openings of the auditory tube. - **Drainage:** All tonsils drain into the superior deep cervical lymph nodes, particularly affecting the jugulodigastric lymph node if infected. #### Clinical Considerations with Lymphatic System Pathology - **Lymphadenopathy:** Dramatic increase in size and change in consistency of lymphoid tissue due to infection or cancer. - **Infection:** Nodes are slightly firmer, extremely mobile, and tender. - **Cancer:** Nodes can become bony hard, fixed to surrounding tissue, usually not tender initially (pain is a late finding). - **Lymphadenitis:** Inflammation of a lymph node, common with microbial infections. - **Metastasis:** Spread of cancer from a primary site to a secondary site via lymph. - Involvement of primary nodes offers a better prognosis than secondary nodes or lymphatic ducts. - Head and neck cancers frequently spread to cervical lymph nodes (80% of cases). - Node metastasis is a significant prognostic factor for squamous cell carcinoma survival. ### Learning Objectives Tasks: - Define and pronounce key and anatomic terms. - Locate and identify glands and associated structures on diagrams, skulls, and patients. - Discuss glandular pathology. - Integrate understanding into clinical dental practice. - List and discuss lymphatic system components. - Locate and identify lymph nodes and tonsils on diagrams and patients. - Identify lymphatic drainage patterns for the head and neck. - Describe and discuss pathology of lymphoid tissue. - Compare the relationship of the lymphatic system to the overall function of the immune system.
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Here is your complete, updated master reviewer for Gizmo. Every table has been converted into clean, plain-text blocks, clear definitions are included for every main section, and concrete examples are integrated under every single term so you can copy and paste it directly into flashcards. 1. Literary Devices & Elements What are Literary Devices and Elements? Literary devices and elements are specific techniques, structures, and tools that authors use to shape their writing, convey deeper meanings, create vivid imagery, and build engaging stories. Figurative Language What is Figurative Language? Words or expressions used with a non-literal meaning to make ideas more vivid, creative, and impactful. * Metaphor: Direct comparison between two unlike things without using "like" or "as". * Example: "Time is a thief." / "His voice was music to her ears." * Simile: Comparison of two things using "like" or "as". * Example: "He ran as fast as the wind." / "Her eyes shined like diamonds." * Personification: Gives human traits, emotions, or actions to non-human objects or abstract concepts. * Example: "The wind whispered secrets through the trees." * Hyperbole: Extreme exaggeration used for emphasis or dramatic effect. * Example: "I'm so hungry I could eat a horse." / "I've told you a million times." * Irony: Expressing meaning using language that normally signifies the opposite (verbal, situational, or dramatic). * Example: A fire station burning down. (Situational Irony) * Oxymoron: Two contradictory or opposite words placed side-by-side. * Example: "Deafening silence," "Bittersweet," "Living dead." Sound Devices What are Sound Devices? Resources used by writers to emphasize the auditory aspects of a text, creating musicality, rhythm, or mood. * Assonance: Repetition of internal vowel sounds within nearby words. * Example: "The rain in Spain stays mainly in the plain." * Alliteration: Repetition of initial consonant sounds in neighboring words. * Example: "Peter Piper picked a pack of pickled peppers." * Consonance: Repetition of consonant sounds, especially at the middle or end of words. * Example: "The million alligators slithered through the mud." * Onomatopoeia: Words that imitate or sound like the real-world noise they describe. * Example: Buzz, crash, hiss, sizzle, boom. * Rhyme, Rhythm, & Repetition: Repeating sounds, beat patterns, or words to create emphasis and musicality. * Example: "Rage, rage against the dying of the light." (Repetition) Maxim, Universal Truth, & Philosophy What are Maxims, Universal Truths, & Philosophies? Statements that reflect general human principles, moral guidance, or shared human experiences. * Maxim: A short, simple saying that gives humans practical advice or a rule of conduct. * Example: "Actions speak louder than words." * Universal Truth: A statement or insight about human life that is true for all people across different times and cultures. * Example: "All humans desire love and belonging." * Philosophy: A foundational belief, worldview, or underlying way of thinking that guides how a person lives or interprets life. * Example: Stoicism teaches that we should focus only on what we can control. Poetic Structure & Style What is Poetic Structure & Style? The architectural layout of a poem, including how lines, sounds, meters, and word choices are organized. * Rhyme Types: * End Rhyme: Words at the end of poetic lines rhyme. * Example: "The cat sat on the mat / It chased a little rat." * Internal Rhyme: Rhyming occurs within a single line of poetry. * Example: "I drove the car to the bar." * Eye Rhyme: Words that look like they should rhyme based on spelling, but sound different when spoken. * Example: Love and Move / Laughter and Slaughter. * Perfect Rhyme: Stressed vowel sounds and all following consonants are identical. * Example: Cat and Hat / Light and Night. * Slant Rhyme: Imperfect or near-rhymes with similar but non-identical sounds. * Example: Shape and Keep / Worm and Swarm. * Meter: The systematic pattern of stressed and unstressed syllables across a line of poetry (composed of poetic feet). * Example: Iambic pentameter ("Da-DUM da-DUM da-DUM da-DUM da-DUM"). * Stanza: A grouped set of lines within a poem (categorized as formal structure or free verse). * Example: A 4-line stanza is called a quatrain. * Diction: The author's deliberate choice of words and phrases: * Formal: Professional, elevated, or academic vocabulary. * Example: "I request your prompt assistance regarding this matter." * Informal: Everyday conversational language. * Example: "Can you give me a hand real quick?" * Slang: Highly casual words specific to a particular group, region, or subculture. * Example: "That idea is total cap." * Concrete: Specific words appealing directly to the five physical senses. * Example: "The freezing, crisp air smelled of pine needles." * Abstract: Broad ideas, feelings, or concepts requiring deeper interpretation. * Example: Concepts like freedom, justice, or truth. Tone, Style & Voice What are Tone, Style & Voice? The elements that define the emotional attitude, writing personality, and perspective of the author or narrator. * Tone: The author's or speaker's attitude toward the subject matter or audience. * Example: Sarcastic, formal, cheerful, or pessimistic. * Mood: The overall emotional atmosphere created by the author's choices, felt by the reader. * Example: Spooky, peaceful, romantic, or tense. * Style: The unique "fingerprint" or manner in which an author writes (Formal, Informal, or Poetic/Evocative). * Meaning Details: Includes Denotation (literal dictionary definition of a word) and Connotation (emotional or secondary meaning attached to a word). * Speaker, Point of View (POV), & Narrative Techniques: * Speaker / POV: Who is speaking or telling the story. * 1st Person: Narrator is a character in the story ("I", "we"). * 3rd Person Limited: Narrator focuses on the internal thoughts of only one character ("he", "she", "they"). * 3rd Person Omniscient: All-knowing narrator who knows the thoughts and feelings of every character. * Persona: The specific character or identity assumed by the writer or speaker. * Narrative Techniques: Methods used to present ideas: * Description: Setting scenes using visual and sensory details. * Flashback: Interrupting the timeline to show an earlier past event. * Reflection: The speaker looking back on an event to ponder its meaning. * Internal Monologue: Showing a character's unbroken flow of inner thoughts. * Dialogue: Spoken conversation between characters. * Example: "'I told you not to enter that room,' whispered Sarah." * Repetition: Intentionally repeating words or phrases for emphasis. 2. Narrative & Literary Analysis What is Narrative & Literary Analysis? The practice of examining the components of a story to understand how it is constructed and to uncover hidden meanings, symbols, and context. Elements of a Story / Narrative What are Narrative Elements? The structural building blocks that make up a story's plot, setting, characterization, and core message. * Plot Structure: The sequence of events in a story: * Exposition: Introduction of characters, setting, and basic situation. * Rising Action: Events and complications leading up to the main conflict. * Climax: The turning point or peak emotional intensity of the story. * Falling Action: Events after the climax that wrap up plot points. * Resolution / Dénouement: The final outcome or resolving of the core conflict. * Setting: Time, geographic location, historical period, and environmental conditions of the story. * Characterization: The methods used to reveal a character's personality: * Direct Characterization: Character traits explicitly stated by the narrator. * Example: "John was a lazy and dishonest boy." * Indirect Characterization (STEAL Method): Trait revealed through clues rather than being told directly: * S – Speech: What they say and how they say it. * Example: "Give me your lunch money right now!" (Shows bully behavior) * T – Thoughts: What is revealed through private inner feelings. * Example: I wish I could help, but I'm too terrified. (Shows internal fear) * E – Effect on others: How other characters react around this person. * Example: Everyone stopped laughing the moment she walked in. (Shows intimidating presence) * A – Actions: How the character behaves in specific situations. * Example: Mark carried the heavy grocery bags for the elderly woman. (Shows kindness) * L – Looks: Physical appearance, clothing, and body language. * Example: Sharply tailored suit, zero wrinkles, every hair in place. (Shows meticulous organization) Signs, Symbols, & Meaning (Semiotics) What is Semiotics? The study of signs, symbols, and how human beings create, interpret, and communicate meaning. * Sign: Anything that points to an idea, piece of information, or object. * Example: A red stop sign on the road. * Symbol: A specific kind of sign holding a deeper, secondary meaning beyond its literal appearance. * Example: A dove representing peace, or a red rose representing love. * Motif: A recurring element, image, object, or pattern that carries symbolic meaning throughout a work. * Example: The constant reappearance of a ticking clock representing running out of time. * Binary Oppositions: Contrasting concepts or pairs put together to highlight thematic conflict. * Example: Light vs. Darkness, Good vs. Evil, Youth vs. Old Age. * The Semiotic Triangle: A model explaining how language links to thought and reality: * Signifier: The physical image, written word, or sound used. * Example: The written word "D-O-G". * Reference: The mental concept, thought, or connotation behind the signifier. * Example: Thinking of a four-legged furry pet that barks. * Referent: The actual physical object or reality being represented. * Example: The real, living dog sitting in front of you. Organic Unity What is Organic Unity? The concept that every single element in a text (symbols, plot, tone, character actions) plays a unique role, yet none can function alone—every element is essential to the overall meaning and structure of the work. Contextual Analysis What is Contextual Analysis? Background information surrounding a literary work that helps readers understand it more deeply and recognize the values behind it. * Historical Context: Historical events, movements, and societal conditions influencing the story's era. * Example: Reading a story set during World War II to understand why food rationing occurs in the plot. * Cultural Context: Shared beliefs, customs, values, and traditions shaping character choices and themes. * Example: Analyzing family traditions and societal expectations in a story set in ancient Asia. * Biographical Context: How the author's real-life experiences and personal background impact their writing. * Example: Knowing Edgar Allan Poe experienced loss helps explain the grief themes in his poetry. * Psychological Context: Mental states, inner motivations, trauma, and psychological behaviors of characters or the author. * Example: Examining how traumatic events affect a main character's choices and fears. 3. Author's Purpose & Rhetorical Modes What is Author's Purpose? The primary reason why an author creates a text (a literary piece can have multiple purposes). To Persuade * Core Intent: Convince the reader to act or adopt a specific belief. * Key Techniques & Features: * Ethos (Credibility / Ethics): Establishing trust, authority, or moral character. * Example: "As a doctor with 20 years of experience, I recommend this treatment." * Pathos (Emotion): Appealing to the reader's feelings (sympathy, fear, joy). * Example: "Don't let innocent shelter animals spend another night in the cold." * Logos (Logic): Using facts, statistics, and logical reasoning. * Example: "Data shows that wearing seatbelts reduces injury risks by 45%." * Call-to-Action (CTA): Directly telling the reader what action to take. * Example: "Sign this petition today to protect our rivers!" To Inform * Core Intent: Educate or share facts objectively without personal bias or subjective views. * Key Features: Textbooks, news reports, informational articles, research papers. To Entertain * Core Intent: Provide enjoyment, amusement, or engagement for the reader. * Key Techniques & Features: * Suspense: Creating anxiety or intense anticipation about what will happen next. * Example: "The footsteps grew louder on the wooden floorboards right outside her bedroom..." * Vivid Storytelling: Using rich sensory details so the reader can visualize the scene. * Example: "The crisp, icy wind whipped through the towering pine trees as the sun dipped below the crimson horizon." To Express Emotions * Core Intent: Share deeply personal, subjective experiences and inner feelings. * Key Features: Uses 1st Person POV ("I", "my"), personal journals, lyric poetry, and emotional reflections. To Explain / Analyze * Core Intent: Blend information with deeper critical insight to help readers thoroughly understand a complex topic. To Teach / Impart Values * Core Intent: Convey a moral lesson, ethical value, or clear guidance to the reader. * Key Features: Fables, parables, allegories, and didactic stories. To Criticize Society * Core Intent: Question and challenge societal norms, political issues, or systemic flaws. * Key Features: Uses satire, irony, allegory, social commentary, and exaggeration. To Reflect Human Experience * Core Intent: Represent human culture, shared traditions, and everyday lived realities. To Inspire * Core Intent: Encourage readers to believe, hold onto hope, and overcome challenges.
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pt 4: Adrenal gland structure Cortex (steroids) + medulla (catecholamines) Three adrenal cortex layers Zona glomerulosa, fasciculata, reticularis Zona glomerulosa Secretes aldosterone (mineralocorticoid) Aldosterone function Increases Na+ reabsorption, K+ excretion; raises blood pressure Aldosterone release triggered by Low BP, high K+, renin-angiotensin system, ACTH Renin-angiotensin system Low BP → renin → Ang I → Ang II → aldosterone + vasoconstriction Zona fasciculata Secretes cortisol (glucocorticoid) Cortisol function Increases glucose, suppresses immune system, maintains blood pressure High cortisol effects Immune suppression, muscle wasting, hyperglycemia Zona reticularis Secretes adrenal androgens Adrenal androgens Weak sex hormones contributing to puberty and libido Adrenal medulla hormones Epinephrine and norepinephrine Epinephrine effects Increases heart rate, metabolic rate Norepinephrine effects Increases vasoconstriction and blood pressure Pancreas function Exocrine (digestive enzymes) + endocrine (insulin, glucagon) Alpha cells in pancreas Produce glucagon Beta cells in pancreas Produce insulin Glucagon function Increases blood glucose via glycogenolysis and gluconeogenesis Insulin function Decreases blood glucose by increasing cellular uptake Somatostatin from pancreas Inhibits insulin and glucagon release Type 1 diabetes Autoimmune destruction of beta cells → no insulin Type 2 diabetes Insulin resistance; cells do not respond to insulin Effects of insulin Promotes glucose uptake, fat storage, glycogen formation Ovarian hormones Estrogen and progesterone Estrogen function Female development, menstrual cycle regulation Progesterone function Maintains uterus for pregnancy Testicular hormone Testosterone Testosterone functions Male traits, sperm production, libido Placental hormones hCG, estrogen, progesterone hCG function Maintains corpus luteum early in pregnancy Kidney hormone EPO (erythropoietin) EPO function Stimulates RBC production when oxygen is low Heart hormone ANP (atrial natriuretic peptide) ANP function Decreases blood pressure by reducing blood volume GI hormones Gastrin, secretin, CCK regulate digestion Skin hormone precursor Produces vitamin D precursor (cholecalciferol) Adipose hormone Leptin Leptin function Signals satiety and regulates metabolism Cushing’s syndrome Excess cortisol → moon face, buffalo hump, high glucose Addison’s disease Low cortisol/aldosterone → fatigue, low BP, hyperpigmentation Pheochromocytoma Adrenal medulla tumor causing excess epinephrine Conn’s syndrome Excess aldosterone → high BP, low K+ Hyperthyroidism symptoms Weight loss, heat intolerance, anxiety, fast heartbeat Hypothyroidism symptoms Fatigue, weight gain, cold intolerance Goiter Enlarged thyroid due to iodine deficiency or overstimulation Primary endocrine disorder Problem in the gland itself Secondary endocrine disorder Problem in pituitary or hypothalamus Calcitriol (active vitamin D) Increases Ca2+ absorption in intestines Endocrine disruptors Chemicals interfering with hormone actions
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pt 4: Adrenal gland structure Cortex (steroids) + medulla (catecholamines) Three adrenal cortex layers Zona glomerulosa, fasciculata, reticularis Zona glomerulosa Secretes aldosterone (mineralocorticoid) Aldosterone function Increases Na+ reabsorption, K+ excretion; raises blood pressure Aldosterone release triggered by Low BP, high K+, renin-angiotensin system, ACTH Renin-angiotensin system Low BP → renin → Ang I → Ang II → aldosterone + vasoconstriction Zona fasciculata Secretes cortisol (glucocorticoid) Cortisol function Increases glucose, suppresses immune system, maintains blood pressure High cortisol effects Immune suppression, muscle wasting, hyperglycemia Zona reticularis Secretes adrenal androgens Adrenal androgens Weak sex hormones contributing to puberty and libido Adrenal medulla hormones Epinephrine and norepinephrine Epinephrine effects Increases heart rate, metabolic rate Norepinephrine effects Increases vasoconstriction and blood pressure Pancreas function Exocrine (digestive enzymes) + endocrine (insulin, glucagon) Alpha cells in pancreas Produce glucagon Beta cells in pancreas Produce insulin Glucagon function Increases blood glucose via glycogenolysis and gluconeogenesis Insulin function Decreases blood glucose by increasing cellular uptake Somatostatin from pancreas Inhibits insulin and glucagon release Type 1 diabetes Autoimmune destruction of beta cells → no insulin Type 2 diabetes Insulin resistance; cells do not respond to insulin Effects of insulin Promotes glucose uptake, fat storage, glycogen formation Ovarian hormones Estrogen and progesterone Estrogen function Female development, menstrual cycle regulation Progesterone function Maintains uterus for pregnancy Testicular hormone Testosterone Testosterone functions Male traits, sperm production, libido Placental hormones hCG, estrogen, progesterone hCG function Maintains corpus luteum early in pregnancy Kidney hormone EPO (erythropoietin) EPO function Stimulates RBC production when oxygen is low Heart hormone ANP (atrial natriuretic peptide) ANP function Decreases blood pressure by reducing blood volume GI hormones Gastrin, secretin, CCK regulate digestion Skin hormone precursor Produces vitamin D precursor (cholecalciferol) Adipose hormone Leptin Leptin function Signals satiety and regulates metabolism Cushing’s syndrome Excess cortisol → moon face, buffalo hump, high glucose Addison’s disease Low cortisol/aldosterone → fatigue, low BP, hyperpigmentation Pheochromocytoma Adrenal medulla tumor causing excess epinephrine Conn’s syndrome Excess aldosterone → high BP, low K+ Hyperthyroidism symptoms Weight loss, heat intolerance, anxiety, fast heartbeat Hypothyroidism symptoms Fatigue, weight gain, cold intolerance Goiter Enlarged thyroid due to iodine deficiency or overstimulation Primary endocrine disorder Problem in the gland itself Secondary endocrine disorder Problem in pituitary or hypothalamus Calcitriol (active vitamin D) Increases Ca2+ absorption in intestines Endocrine disruptors Chemicals interfering with hormone actions
49
Updated 5d ago
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