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Cell Communication and Cell Cycle
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Signal Transduction Pathway
A series of steps linking a mechanicaSl, chemical, or electrical stimulus to a specific cellular response; synaptic type of chemical signaling; Example: neurons communicate by releasing neurotransmitters across a synapse to stimulate the target cell
Kinase Enzyme
Catalyzes the transfer of phosphate groups
Ion Channel Receptor
Stop or allow flow of ions into the cell; type of receptor
Intracellular Receptor
Found in the nucleus or cytoplasm of the cell; bond to chemical messengers that are hydrophobic or very small, like nitric oxide
Protein Kinase
Transfers phosphate groups from ATP to a protein
First Messenger
Signaling molecule; extracellular; not ligand
Second Messenger
Intracellular; either a water-soluble molecule or an ion; type of messenger
Apoptosis
Cellular agents chop up DNA and fragment the organelles and other cytoplasmic components
Reception
The target cell's detection of a signaling molecule coming from outside the cell
Transduction
Happens after the receptor protein is changed by the signaling molecule; converts the signal to a form that can bring about a specific cellular response
Response
Type of cellular activity triggered by the transduced signal
Ligand
The term for a molecule that specifically binds to another molecule, usually a larger one; another name for a signaling molecule
Tyrosine Kinase
Attaches phosphates to tyrosines; catalyzes transfer of a phosphate group from ATP to tyrosine (an amino acid) on a substrate protein
cAMP
Made from ATP by adenylyl cyclase; inactivated by phosphodiesterase; a common type of second messenger
Amplification
The strengthening of stimulus energy during transduction.
G-Linked Protein Receptor
receives message for g-linked protein signaling pathway. Consists of seven alpha helices that span the plasma membrane. Changes shape when ligand molecule binds.
Cell Division
the process of creating two new cells
Mitosis
when the nucleus itself divides into two new nuclei
Cytokinesis
when the rest of the cell divides to form two new daughter cells
Chromatin
when the DNA inside the nucleus appears as disorganized, long strands
Chromosomes
when the DNA coils tightly, shortens and thickens prior to mitosis
DNA Molecule
another name for a chromosome; contains the genes
Replication
the process of chromosomes making exact duplicates
Sister Chromatids
the two sides of the "X" formed by replicated chromosomes
Centromere
a central protein bundle that connects sister chromatids
Autosomes
all chromosomes except for the sex chromosomes
Genes
codes within DNA that specify a particular trait
Alleles
two alternate forms of each gene (such as blue eyes or browneyes)
Somatic Cells
All of the body cells
Gametes
sperm and egg cells, also referred to as sex cells
Diploid Number
the total number of chromosomes in normal body cells; two matching homologs of each kind
Cell Cycle
the entire life cycle of the parent cell
Interphase
the cell is carrying out its normal everyday cell activities as well as preparing for the Mitotic phase
G1 and G2 Phases
gap phases; G1 is mostly growth and development G2 occurs after replication of chromosomes and involves replication of additional organelles and membranes in preparation for cell division
S Phase
synthesis of new DNA; also called replication
Prophase
the first phase of mitosis characterized by a disappearance of the nuclear membrane and nucleolus
Spindle Blanket
This structure will assist in pulling apart the doubled chromosomes
Metaphase
the second phase of mitosis where all of the doubled chromosomes move to the center of the cell, called the equator
Anaphase
the third phase of mitosis where the spindle fiber shorten from the poles, pulling the doubled chromosomes apart from each other, toward the poles of the cell
Telophase
the final phase of mitosis characterized by the separated chromosomes reaching the poles of the cell. The nuclear membrane and nucleolus begins to reappear around each set of chromosomes
Cell Plate
a structure which eventually forms a cell wall that begins to grow out from the center and merely separates the two daughter cells
Microtubule
organizing center which performs the job of the centriole in plants These terms refer specifically