What are some drugs that can induce hyperthyroidism?
Iodine-containing contrast dyes
Amiodarone
Iodinated glycerol
Alpha-Interferon
Alemtuzumab (anti-CD52)
TH (T3, T4)
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What are the advantages of surgery to treat hyperthyroidism?
* Definitive * TOC - Malignancy * TOC - Respiratory or swallowing difficulties * Existence of CI’s to RAI/Thioamides * Non-compliant pt
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What are the disadvantages of surgery to treat hyperthyroidism?
* Risks of hypothyroidism * surgical risks * Cosmetic consequences * Must safeguard against Thyroid Storm
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What are the advantages of Radioactive Iodine therapy for hyperthyroidism?
* Definitive * Alternative for non-surgical candidates * Pts who fail or experience ADR to drug therapy * Pts in which disease recurrence would complicate other diseases * Non-compliant pt
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What are the disadvantages of radioactive iodine therapy for hyperthyroidism?
* Risk of hypothyroidism * CI in pregnant or nursing mothers * Concern of use in children * possible radiation thyroiditis * must safeguard against Thyroid Storm
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What are the advantages of drug therapy for hyperthyroidism?
* Noninvasive * Minimize chances of hypothyroidism * Use in pts with CI to surgery/RAI
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What are the disadvantages of drug therapy for hyperthyroidism?
* Not definitive treatment * *possible medication SE* * requires long term compliance
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What is functional unit of the thyroid gland?
FOLLICLES
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What are the key elements that function within the follicle?