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What does ASLS -(Advanced Stroke Life Support) use for their primary exam?
MEND Exam - Miami Emergency Neurologic exam
What is the emergency neurological life support for ?
15 hour training curriculum teaching protocols regarding strokes
what is the difference between an EMT and paramedic?
paramedics receive much more training and can start IV's and give injections
What is the golden hour?
the time from patient arrival until IV tPA is administrated
what is the door to stroke unit admission time?
less than 3 hours
what is the only lab test required prior to thrombolytic treatment?
blood glucose - you do not need an INR!!!
What blood sugar level is associated with worse outcomes during the first 24 hours ?
Blood sugar levels greater than 200
What is the difference between TPA and TNK?
TPA is a bolus plus 1 hr infusion
TNK is the modified form of TPA
approved for MI patients not strokes; can be given in a single IV bolus in 5-10 seconds
Each 15 minute reduction in door to needle time results in what post care for strokes?
an additional month of disability free life after stroke
With patients who stroke is considered mild, NIH <4, should we still treat with TPA? Is there a risk for a bleed?
Yes administer TPA, improves outcomes, no greater risk for bleed
What CT would indicate a patient cannot recieve TPA?
Ischemic Injury involving more than 1/3 of an MCA or severe hypo density indicating irreversible damage
What platelet level is contraindicated for TPA?
<100,000
What aPTT or PT level is contraindicated for TPA?
>40sec >15sec
What time frame can we give TPA?
FDA approved to be given within 3 hours
Can be extended to 4.5
If the patient does not receive a fibrinolytic, what anticoagulant should we expect to administer?
ASA 300 mg rectally or ASA 325 by mouth after swallow eval
When TPA is finished, how should we flush the line?
Hang the NS at the same rate to completely flush the line
Tenecteplase administration
Dosage calculation: 0.25 mg/kg as IV bolus over 5 seconds
BP must be maintained <180/105 for first 24 hours post thrombolytic administration
Are all patients who have an LVO considered for a thrombectomy, who have been given TNK?
Yes
What is number one complication for IV TPA?
ICH
What medications do we give when a patient has an angioedma reaction to TPA?
Methylpredisone
Benadryl
Famotidine
Epinephrine
When would rapid intubation be required for patients who have angioedma reaction from TPA?
Rapid progression of symptoms
What is the time frame to begin the start of the procedure for a thrombectomy ?
Within 24 hours of the LKW
What is the time goal for ED to skin puncture ?
90 minutes
What is the time goal for skin puncture if patients are transferred from another stroke center?
60 minutes
What is the recommended thrombectomy device by the ASA?
Stent Retrievers
What TICI grades are considered to be successful outcomes?
TICI 2B and 3
When is intra-arterial thrombolytic therapy considered?
as an add on following mechanical thrombectomy
What is DIDO (Door in, door out)?
time from arrival to ICU admission
What is the time goal for DIDO?
2 hrs
what is telestroke?
access to acute stroke care in underserved areas
What does telestroke involve ?
A neurology expert can view and interact with the patient
How does telestroke help with initial evaluation of a stroke?
1. It is proven to shorten DTN times
2. Identifies patients who transfers are indicated and those who are not
How would a telestroke technology help out with a patient with an ischemic stroke vs a patient with a devastating hemorrhagic stroke?
A small ischemic stroke can by managed by a community hospital where a devastating hemorrhagic stroke has no acute intervention - comfort measures can be provided
What is the quickest way to get to a neurological evaluation for a suspected stroke?
911
What is the most common reason for stroke patients not getting TNK/TPA or stroke reperfusion therapy?
Delay in patients getting to the hospital
EMS should not bypass the closest non-stroke certified hospital if diversion would add more than ______ minutes to the transport time
20
How are prehospital stroke policies determined?
They vary from state to state and are divided into regions/districts that function independently
What are the 5 D's of posterior strokes?
Dipoplia, Dizziness, Dysarthria, Dysphagia, Dystaxia
Which type of stroke is most commonly misdiagnosed in the ED with what age group of people?
Posterior strokes most commonly in young patients
What is no longer a standard in stroke workup?
Chest X-ray
What is an indicator for less optimal outcomes for thrombectomy?
older than 80
What is the most effective way in improving prehospital stroke care?
Patient specific feedback
What does hyper acute care include ?
Prehospital Care and ED Care
What type of care refers to the time period where in the first 24 hours after an acute onset of a stroke a stroke patient received urgent and emergency evaluation of symptoms and is eligible IV therapies ?
Hyperacute phase I
What is the stroke chain of survival ?
Detection
Dispatch
Delivery
Door
Data
Decision
Drug
Disposition
Should we treat BP before arriving at the hospital ?
No, contact the ED en route to treat the BP
What is the on scene time of EMS?
15 minutes
When is air transport reasonable ?
When ground transport takes greater than 1 hour
What are considered designated stroke centers?
Acute Ready Stroke Center that has telemedicine and tele radiology capabilities
Primary Stroke Center
Thrombectomy capable stroke centers
Comprehensive stroke centers
What are the 3 different types of prehospital screening stroke scales?
Los Angelos Stroke Scale
Cincinnati Scale
RACE Scale
What signs and symtptoms does the Los Angelos Stroke Scale detect?
Facial droop, arm drift, grip strength, finger stick
What signs and symptoms does the Cincinnati Scale detect?
Facial droop, arm drift, abnormal speech
Which prehospital screening takes less time?
Cincinnati Prehospital Stroke Scale
Which prehospital screening is more accurate and in-depth?
Los Angelos Stroke Scale
What is the R.A.C.E. Scale?
Rapid neurological scale with increased probability of having an LVO
What does sensitivity mean on the RACE scale?
occlusion
What does specificity mean on the RACE scale
doesn't give you an exact location
During prehospital transportation, if patient is hypotensive, what should EMS do?
place head stretcher flat and and administer isotonic saline to improve cerebral edema
During prehospital transportation, if patient is hypoglycemic what should EMS do?
administer dextrose
What is "Drip and Ship?"
tPA initiated in a rural hospital and immediately transferred to a stroke center
What is Todds Paralysis/Paresis?
brief period of transient paralysis following a seizure
Why could a conversion disorder mimic a stroke?
A conversion disorder is a brief period of acute stress but during an objective exam, nothing shows up (NIH wise)
At what hypoglycemic level would glucose mimic a stroke?
Less than 45
What is the difference between Bell's Palsy and a stroke?
Bells Palsy will take awhile for symptom onset
Cranial Nerve 7 is pinched
What NIH score indicates a minor stroke?
0-4
What NIH score indicates a moderate stroke?
5-15
What NIH score indicates moderate to severe stroke?
16-20
What NIH score indicates a severe stroke?
>21
when is NIHSS performed baseline ?
Obtained rapidly in the ED
What is the score range of the NIH?
0-42
What NIH score predicts patient will have good or excellent outcomes?
NIH < 14
What is the Hunt and Hess Score associated with?
SAH
What does a 0 mean with the Hunt and Hess Scale?
no symptoms
What does a 2 mean with the Hunt and Hess Scale?
worst headache of life
What does a 3 mean with the Hunt and Hess Scale?
LOC decline
What does a 4 mean with the Hunt and Hess Scale?
Patient is posturing
What does a 5 mean with the Hunt and Hess Scale?
Deep Coma
What is the ABCD2 score?
(Age, BP, Clinical features, Duration of symptoms, & Diabetes) Used to identify pts at high risk of ischemic stroke in the first 7 days after TIA
Has a range from 1-7
What ABCD2 score indicates admission is advised ?
Greater or equal to 4
What ABCD2 score indicated discharge is advised ?
Less than 4
What does A stand for in the ABCD score?
Age greater than 60
What does B stand for in the ABCD score?
Blood Pressure >140/90
What does C stand for in the ADCD2 score?
Clinical Features
1 - Speech disturbance only
2- Unilateral weakness
What does D stand for in the ABCD2 score?
Duration of symptoms
60 minutes - 2 points
10-59 minutes - 1 point
What does D2 stand for in the ABCD2 score?
Diabetes if it is present
What score in the ABCD2 score indicates a patient is at a high risk of a stroke ?
6-7
When are ED nurses able to perform a rapid neurological assessements on patients?
During the time when the patient is in the stretcher while moving the patient to CT
If stroke symptoms completely resolves after CT and they come back, what do we consider the time of symptom onset?
Second set of symptoms
If someone "woke up" and had a stroke , what would be there time of last known normal?
When the patient to be last normal, or before falling asleep
What baseline common lab work do we perform prior to giving Alteplase ? What if the patient is on an anticoagulant?
CT and finger stick; then they will need a PTT/INR
The only thing that needs to delay a patients IV TPA:
anticoagulation use
Do we draw baseline troponin or ekg's in cardiac patients ?
no
What is considered the gold standard for detecting a stroke?
Diffusion weighted sequence MRI
Once code stroke is called, what fluids do we start on patients?
Isotonic Saline
What is the goal for fluids for a stroke patient?
To make them euvolemic
What type of breathing patterns are frequently seen in stroke patients ?
Cheyne Stokes breathing
When does BP management begin for stroke patients?
In the ED
What are the three BP medications we use to treat BP
Labetalol
Nicardipine
Clevidipine
We get our patient to CT, and we realize that on the CT is shows an ICH, what should we expect our BP goals to be changed too?
<140
Intra-arterial fibrinolysis is beneficial for patients with major strokes caused by MCA occlusion within how many hours?
6 hours