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Thrombocytes
Platelets; clot blood
Blood
Transports foods, gases, and wastes to and from the cells of the body
What are some things that the blood transports?
Chemical messengers or hormones. Blood proteins, white blood cells, and platelets
45% of blood is made up of…
Cells
55% of blood is made up of…
Plasma, water, proteins, sugar, salts, hormones, lipids, vitamins
Erythrocytes
red blood cells transport nutrients and oxygen
Leukocytes
White blood cells
Basophils
Contains heparin and histamine
What does heparin do?
Prevents clotting (in basophils)
What is histamine involved in?
Allergic responses
Lymphocytes
Control the immune response; make antibodies to antigens
Eosinophils
phagocytic cells involved in allergic responses and parasitic infections
Neutrophils
phagocytic cells that accumulate at sites of infection
Monocytes
phagocytic cells that become macrophages and digest bacteria and tissue debris
Albumin (plasma protein)
Protein in the blood; Maintains concentration of water in blood
Globulins (plasma protein)
Immunoglobulins (IgG, IgA, IgM, IgD, IgE)
Fibrinogen
Plasma protein for clotting
Prothrombin
Plasma protein for clotting
Type A blood
A antigen and anti-B antibody
Type B blood
B antigen and anti-A antibody
Type AB blood
A and B antigens and no antibodies (universal recipient)
Type O blood
no A or B antigens and both anti-A and anti-B antibodies (universal donor)
Rh factor
Antigen on red blood cells of Rh-positive (RH+) individuals
Coagulation
Fibrin clot
Anticoagulants
Heparin, warfarin (Coumadin)
Antibody (Ab)
A specific protein produced by the lymphocytes in response to bacteria, viruses, or other antigens
Antigen
A substance that stimulates production of an antibody
What color do basophils appear on a stain?
Blue
What types of WBC contain granules?
Basophil, Eosinophil, Neutrophil
Bilirubin
Orange-yellow pigment in bile; formed by breakdown of hemoglobin when RBCs are destroyed
Colony-stimulating factor (CSF)
Protein that stimulates growth of white blood cells
Differentiation
The change in structure and function of a cell as it matures; specialization
Electrophoresis
A method of separating serum proteins by electrical charge
What color do Eosinophils appear on a stain?
Red
Erythroblast
An immature red blood cells
Erythrocyte
A red blood cell
erythropoietin (EPO)
Hormone secreted by the kidneys that stimulates red blood cell formation
Fibrin
Protein that forms the basis of a blood clot
Fibrinogen
Plasma protein that is converted to fibrin in the clotting process
Globulin
Plasma protein
Granulocyte
White blood cell with numerous dark-staining granules
Hematopoietic stem cell
A cell in bone marrow that gives rise to all types of blood cells
Hemoglobin
Blood protein containing iron; carries oxygen in red blood cells
Hemolysis
Destruction or breakdown of blood (red blood cells)
Heparin
An anticoagulant found in blood and tissue cells
Immune reaction
Response of the immune system to foreign invasion
Immunoglobulin
A protein with antibody activity
Leukocyte
White blood cell
Lymphocyte
Mononuclear leukocyte that produces antibodies
Macrophage
engulfs foreign material and debris; destroys worn out RBCs
megakaryocyte
Large platelet precursor cell found in the bone marrow
Monocyte
Has 1 nucleus. engulfs foreign material and debris; becomes macrophage
Mononuclear
Pertaining to cell (leukocyte) with single round nucleus
Myeloblast
Immature bone marrow that gives rise to granulocytes
Neutrophil
polymorphonuclear leukocyte, formed in bone marrow
Plasma
Liquid portion of blood
What does plasma contain?
water, proteins, salts, nutrients, lipids, hormones, and vitamins
plasmapheresis
Removal of plasma from withdrawn blood by centrifuge
Platelet
A small blood fragment important in clotting
Polymorphonuclear
Pertaining to a white blood cell with multi-shaped nucleus; neutrophil
Prothrombin
Plasma protein; converted to thrombin in the clotting process
Reticulocyte
Immature erythrocyte
Serum
Plasma minus clotting proteins and cells
Stem cell
Unspecialized cell that gives rise to mature,specialized forms
Thrombin
Enzyme that converts fibrinogen to fibrin during coagulation
Thrombocyte
Platelets
bas/o
Base
chrom/o
Color
coagul/o
clotting
cyt/o
cell
eosin/o
red, dawn, rosy
erythr/o
red
granul/o
granules
hem/o
blood
hemat/o
blood
hemoglobin/o
hemoglobin
is/o
same, equal
kary/o
nucleus
Leuk/o
white
Mon/o
One, single
Morph/o
Shape, form
Myel/o
Bone marrow
Neutr/o
neutral
Nucle/o
nucleus
phag/o
eat, swallow
poikil/o
varied, irregular
sider/o
iron
spher/o
globe, round
thromb/o
clot
Anemia
A deficiency in erythrocytes or hemoglobin
Aplastic anemia
failure of blood cell production due to aplasia or absence of cell formation of bone marrow cells
Hemolytic anemia
reduction in red cells due to excessive destruction
Pernicious anemia
lack of mature erythrocytes caused by inability to absorb vitamin B12 into the bloodstream
Sickle cell
hereditary disorder of abnormal hemoglobin producing sickle shape erythrocytes and hemolysis
Thalassemia
an inherited defect in the ability to produce hemoglobin, leading to hypochromia
Hemochromatosis
excess iron deposits throughout the body
Polycythemia vera
general increase in red blood cells
Hemophilia
excessive bleeding caused by the lack of one of the protein substances necessary for blood clotting
Purpura
multiple pinpoint hemorrhages and accumulation of blood under the skin
Leukemia
an increase in cancerous white blood cells