Salivary Gland Neoplasms

what is the most common salivary gland tumor of ALL, benign and malignany?

pleomorphic adenoma

what is the most common SITE of pleomorphic adenoma?

palate

what is the most common MALIGNANT salivary gland tumor?

mucoepidermoid carcinoma (MEC)

what is the most common MALIGNANT salivary gland tumor in MAJOR salivary glands?

mucoepidermoid carcinoma (MEC)

what is the most common MALIGNANT salivary gland tumor in MINOR salivary glands?

adenoid cystic carcinoma

what are two common sites for MALIGNANT NEOPLASMS?

• retromolar pad

• sublingual

what is the most common SITE of neoplasms for MAJOR salivary glands?

parotid gland

what is the most common SITE of neoplasms for MINOR salivary glands?

palate, upper lip

(t/f) approximately 6% of all head and neck neoplasms are salivary gland neoplasms

true

(t/f) salivary gland neoplasms have a slight FEMALE predilection

true

polymorphous adenocarcinoma

2nd most common minor salivary gland malignancy

• female

• almost exclusive to minor salivary glands

• posterior palate

adenoid cystic carcinoma

most common malignancy of the submandibular gland

• 50% palate

• pain, aggressive

• histology shows perineural invasion (pain), swiss cheese

• later recurrence

pleomorphic adenoma (PA) mixed tumor

most common SG tumor of all

• parotid (major) palate (minor)

• painless, slowly growing firm mass

• tumor is encapsulated

• tx surgical excision gives best prognosis of all tumors

what is a concern for pleomorphic adenoma (PA) mixed tumor?

5% become malignant! carcinoma ex-pleomorphic adenoma

synonym for warthin tumor?

papillary cystadenoma lymphomatosum

warthin’s tumor

• almost exclusive to tail of parotid gland

• 55-60 year olds

• strong association with cigarette smoking

• unilateral or bilateral

synonym for canalicular adenoma

monomorphic adenoma

canalicular adenoma

• minor salivary glands

• upper lip

• >60 years old

• slow growing, painless submucosal mass

mucoepidermoid carcinoma

most common SG malignancy

• appears as an asymptomatic swelling

• intraosseous tumors can develop in jaws

• < 15 years old is common

tx variations for mucoepidermoid carcinoma

low grade — wide surgical excision, 95% 10 year survival rate

high grade — surgical + radiation, 40% 10 year survival rate