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the ____ converts a signal of interest into analog voltage
transducer
the voltage carried is amplified and filtered
signal conditioning
signal conditioning can also include this process to remove an unwanted, steady offset
zeroing
number of occurrences of a repeating event per unit time
Frequency
the height of the wave from baseline to crest
amplitude
is the shape and form of a signal
waveform
is the length from the crest of one peak to the crest of the next peak
wavelength
three types of muscle tissues
cardiac, skeletal, smooth
common prefixes for muscle related
myo, mys, sacro
what kind of cells make up 40% of the cell mass
skeletal muscle cells
skeletal muscle function
work locomotion and support of the body
muscle fibers
muscle cells
muscle fibers are organized in bundles caled
fascicles
muscles used the chemical energy stored in ____ to produce mechanical energy
ATP
a type of neuron damage due to stroke
upper motor neuron lesions
skeletal muscle control is
voluntary
skeletal muscle is ____, but ____ rapidly
powerful; tires
all muscle cell membranes have an electric charged differential which can be changed upon stimulation to ultimately produce an intracellular muscle response
excitability
muscle cells will shorten when stimulated
contractility
all muscle cells can be stretched, sometimes more than their resting length
extensibility
muscle cells that can recoil to their original length after being stretched are called
elasticity
muscles also have
nerves, blood vessels, and connective tissues
muscle tissue that connects to bone
tendons
tendons help the muscle move the ___
bone
the bone that moves is called the
insertion
the bone that doesnt move
origin
if the periosteum or perimysium is fused to the muscle’s epimysium this is called
direct attachments
a tendon, or aponeurosis for example is a type of
indirect attachment
muscles usually work antagonistically meaning
when one muscle contracts and shortens, the other relaxes and elongates
skeletal cells are
multinucleated
plasma membrane of the cell is called
sarcolemma
cytoplasm of the cell
sarcoplasm
part of the muscle cell that stores oxygen
myoglobin
granules of glycogen that can be broken down to supply ATP
glycosomes
repeating structures of sarcomeres are called
myofibrils
are the smallest atomic “contractile” units of skeletal muscle fibers
sarcomeres
the reason muscle cells are striated
dark A bands and light I bands
each a band has a middle region that is slightly lighter. this is called the
h band
the i band has a dark midline region termed the
z line
the sarcomere runs from the
z line to z line
another name for thick filament
myosin
myosin proteins contain
protruding globular heads
the m band connects
thick filaments in the middle of the sarcomere
the myosin bands only have globular heads where they overlap with
actin or thin filaments
when a muscle contracts, myosin heads link the thin and thick filaments together, which are called
cross bridges
cross bridges swivel as motors to do what to the sarcomere?
shortens
each thick filament can have up to how many myosin molecules
300
tropomyosin
blocks actin’s myosin-binding
troponin
composed of 3 globular polypeptides, each having a different function. One binds to tropomyosin, one binds to actin, and the last binds to calcium
elastic filaments are made of the protein
titin
elastic filaments
run from the z line to the thick filaments to hold them in place and allow for recoil in the muscle cells
when titin reaches it’s normal extension
it stiffens and resists further over stretching of the muscle
smooth ER equivalent in the muscle cells
sarcoplasmic reticulum
at the a band and i band junction, the sarcoplasmic reticulum forms large perpendicular cross channels called
terminal cisterns
mitochondria and glycogen granules are highly abundant where?
near the sarcoplasmic reticulum
terminal cisterns are always found in?
pairs
sarcoplasmic reticulum controls?
calcium levels, and releases calcium to control muscle contraction
at the a band and i band junction, elongated tubular extensions of the sarcolemma dive deep into the cell and are called
t tubules
t tubule plus terminal cisterns on either side are called
triads
electrical signal travels down where
sarcolemmas, and can be carried through the t tubules, since they’re extensions of sarcolemmas
the electrical signal stimulates the release of ____ from terminal cisterns
calcium
integral proteins of create gated channels for the RELEASE of ____
CALCIUM
sarcolemma carries a resting charge, polarization, where the inside of the cell is more _____ relative to the outside
negative
how many steps are there to the propogation of a muscle action potential
3
what is step one of the muscle action potential
acetylcholine binds to its receptor → opens the voltage gate for sodium → makes the inner surface of sarcolemma negatively charged (depolarization). happens at the end of the plate and is termed the end plate potential
step two of muscle action potential
voltage gated sodium channels respond to the charge change andopen, allowing sodium ions to rush into the cell, further depolarizing the membrane → called the muscle action potential
step three of muscle action potential
once the voltage gate is positive enough, the potassium gates open → allowing potassium to exit the cell, resulting in repolarization of the membrane.
gradient differences are restores by this pump
ATPase pump
while repolarization is occuring, this period is marked by the inability to contract for about a millisecond
refractory period
events to the contraction of the muscle are collectively referred to as
excitation-contraction coupling
when calcium is low, this protein blocks myosin receptors
tropomyosin
the force exerted by a contracting muscle on an object
muscle tension
the opposing force applied on teh muscle by the mass of the object being moved
load
the motor neuron, along with all the individual muscle fibers that get innervated are called
motor units
motor units vary in ____ & ____
size and function
the smaller the motor unit, the more ____ the muscle is controlled
finely
specific motor units only have how many neurons?
1