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what is the anatomy of the urinary system
2 kidneys, 2 ureters, urinary bladder, urethra
what is a nephron
microscopic structure and functional unit of the kidney
what is the name of the “cleaning unit”
glomerus
what is the primary function of the kidney
homeostasis
what happens when the kidney is in negative balance
conserves water and electrolytes
what happens when the kidney is in positive balance
excretes water and electrolytes
what are functions of the kidney
maintain pH, conserve nutrients - renal tubules, excretion of nitrogenous end products, regulates blood pressure, stimulates RBC production, produces prostaglandins, and aids in vitamin D activation
what hormone regulates blood pressure
renin
what hormone stimulates erythrocyte production
erythropoietin
what does BUN stand for?
Blood Urea Nitrogen
True or False EDTA blood can be used to evaluate kidney function
false
what is the gold standard for urine collection
first morning sample
what does the kidneys filter
blood
frequent urination is termed
pollakiuria
straining to urinate is termed
oliguria
vocalizing with no urination and excessive licking indicates
pain
increased urination is termed
polyuria
increased water consumption is termed
polydipsia
what is another name for free catch
voided
what is the con of voided
contaminants
what collection is gentle pressure applied to bladder to cause release of urine
bladder expression
what urine collection is passed through urethra into bladder
urinary catheterization
what is the gold standard of urine collection methods
cystocentesis
what urine collection is a surgical puncture through abdomen into bladder
cystocentesis
what is a must with cystocentesis
aseptic technique
how long after collection is it ideal to evaluate urine
30 minutes
what can bladder expression cause
RBC due to force
what type of catheter has a balloon on the end
foley catheter
what size needle is typical for cystocentesis
1.5 inch, 22 gauge
how many attempts do you have with a cystocentesis
3
True or False: you can redirect with cystocentesis
false
how long will refrigerating preserve urine for
6-12 hours
what should be done first when evaluating urine
chemical analysis
in females what is needed to place a catheter
vaginal speculum
in female dogs where is the urethral opening located
on vaginal floor
with a cystocentesis where should the needle be placed
cranial to the junction of bladder and urethra
what is included in the macroscopic exam
physical exam and chemical exam
what is included in microscopic exam
cells, crystals, microorganisms
what is the normal urine production for dogs and cats
20-40 ml/kg/d
what is the normal urine production of cattle
17-45 ml/kg/d
what is the normal urine production for horses
3-8 ml/kg/d
what is the normal urine production for sheep/goat
10-40 mL/kg/d
what is associated with polyuria
polydipsia
what is the normal color, concentration, and sg of polyuria
pale, dilute, and low sg
which diabetes is when an animal can not save water but blood glucose in normal
diabetes insipidus
what is no urine production termed
anuria
what is normal urine color
little yellow to amber
what does pale yellow urine indicate
dilute, low sg, polyuria
what does very yellow/ yellow brown urine indicate
concentrated, high sg, oliguria
what does brown/green urine indicate
concentrated, bile pigments when it foams upon shaking
what is floating particles called
flocculent
what is a normal specific gravity and what is it termed
1.007-1.013, isosthenuria
what is an increased specific gravity called
hypersthenuria
what is a decreased specific gravity called
hyposthenuria
what does red/brown urine indicate
myoglobinuria or muscle lysis
what does red urine indicate
hematuria or hemoglobinuria
what does orange/green/blue urine indicate
drug or vitamins
what is hematuria
intact RBC
how can you tell if a sample is hematuria after centrifuge
sediment red and supernatant clear
how can you tell if a sample if hemoglobin
supernatant is red
after adding ammonium sulfate how can you distinguish hemoglobin vs myoglobin
hemoglobin’s supernatant is clear while myoglobin’s is red/brown
what species has a cloudy urine due to calcium carbonate and mucus
equine
what species has milky urine due to calcium carbonate
rabbits
what is hemoglobin in urine show as
ghost cells
what can slightly cloudy urine indicate
sperm or mucous
what odor does cystitis have
ammonia
what odor does ketones have
sweet/fruit/alcohol
what is specific gravity
density of a liquid compared to distilled water
what is the normal specific gravity for canine
1.001-1.060
what is the normal specific gravity for feline
1.001-1.080
what can concentrated urine indicate
dehydration
an increased specific gravity indicates what
dehydration (decrease in water intake or increase in fluid loss), renal failure, shock
a decreased specific gravity indicates what
kidney can’t resorb water (increase in fluid intake)
what affects pH
diet
what is the pH of herbivores
alkaline: 7.0-8.5
what is the pH of carnivores
acidic: 6.0-7.0
what is the pH of omnivores
either basic or acidic
what happens to the pH when urine is at room temperature?
increases
what happens to urine standing at room temp
urease-producing bacteria increases
what is the term of protein present
proteinuria
what does the sulfosalicylic acid turbidity test determine
urine protein by acid precipitation
what protein does dipstick pick up on
albumin
what is the presence of glucose termed
glucosuria or glycosuria
what must glucose have excessed
renal threshold (170-180 mg/dl)
what does hyperglycemia and glucosuria indicate
diabetes mellitus
true or false: stress can cause glucose to be present in urine
true
what is the main energy source
glucose
what causes glucose
carbohydrate breakdown
what is the presence of ketones termed
ketonuria
true or false: increased levels of fat metabolism are toxic
true
what is ketosis (ketonemia) common in
large animals
what is the presence of bilirubin termed
bilirubinuria
what bile pigments are picked up on chemical dip stick
conjugated bilirubin only
what is urobiliogen
by-product
what type of blood is not visible
occult blood
what is the presence of leukocytes termed
pyuria or leucouria
what must always be confirmed microscopically
leukocytes
centrifuge settings for urine
1500 RPM for 5 minutes
what is viewed on high power field
cells
what is viewed on low power field
crystals and casts