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Na+K+ antiporter
(plasma membrane → ER)
ERSS
SRP receptor
Acid-dependent protease
(lysosome)
ERSS, m6p
SRP, m6p receptor
Histone
(nucleus)
KKKRP (NLS)
Nuclear receptor (NIR)
Extracellular matrix protein
(secreted out of the cell, ER → golgi)
ERSS
SRP
Galactosyl transferase
(makes oligosaccharides)
ERSS
SRP
BiP
(ER resident protein)
ERSS, KDEL
SRP, KDEL receptor
RNA polymerase
NLS
NIR
Ribosomes attatch to the ER
SRP, ERSS
SRP receptor
Ribosomes stay free in cytosol
Remains in cytosol
no signal or receptor
Remains in ER
KDEL, ERSS(to get into and stay in ER)
KDEL, SRP
Move into lysosome
m6p, ERSS
m6p, SRP
Move into secretory vesicle
ERSS
SRP
Moves into nucleus
NLS
NIR