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Integration of Nervous System Functions
Study of how the nervous system processes sensory input, produces responses, and stores information
Sensation
Process initiated by stimuli acting on sensory receptors
Perception
Conscious awareness of sensations
Senses
Means by which the brain receives information about the environment and body
General senses
Widely distributed throughout the body
Special senses
Located in specialized organs (smell, taste, vision, hearing, balance)
Somatic senses
Touch, pressure, temperature, proprioception, and pain
Visceral senses
Pain and pressure from internal organs
Generator potential
Graded potential in general sensory receptors that leads to action potentials
Receptor potential
Graded potential in special sensory receptors that leads to neurotransmitter release
Mechanoreceptors
Detect compression, bending, stretching; involved in touch, pressure, proprioception, hearing, balance
Chemoreceptors
Respond to chemical binding; involved in smell and taste
Thermoreceptors
Detect temperature changes
Photoreceptors
Respond to light (vision)
Nociceptors
Detect extreme mechanical, chemical, or thermal stimuli (pain)
Cutaneous receptors
Sensory receptors located in the skin
Visceroreceptors
Sensory receptors associated with internal organs
Proprioceptors
Sensory receptors in joints and tendons that detect stretch and body position
Free nerve endings
Simple sensory receptor type that detects pain and temperature
Merkel disk
Receptor for light touch, slow adapting
Hair follicle receptor
Detects hair movement
Pacinian corpuscle
Detects deep pressure and vibration, rapidly adapting
Meissner corpuscle
Detects light touch, rapidly adapting
Ruffini end organ
Detects skin stretch, slow adapting
Muscle spindle
Detects muscle length and stretch; involved in muscle tone and stretch reflex
Golgi tendon organ
Detects tension in tendons
Graded potential
Change in membrane potential due to stimulus interaction with receptor
Primary receptor
Sensory receptor whose axon generates action potentials directly
Secondary receptor
Sensory receptor that releases neurotransmitters to stimulate a neuron
Primary receptor example
Pacinian corpuscle generating action potentials directly
Secondary receptor example
Taste cell releasing neurotransmitter to sensory neuron
Threshold
Level at which a receptor potential triggers action potentials
Central nervous system (CNS)
Brain and spinal cord where sensory signals are processed
Adaptation
Reduced sensitivity to a continuous stimulus
Tonic receptors
Slow-adapting receptors that respond to continuous stimuli
Phasic receptors
Rapidly adapting receptors that respond to changes in stimuli
Pain
Unpleasant sensory and emotional experience triggering autonomic, psychological, and motor responses
Fast pain
Sharp, localized pain carried by large myelinated axons
Slow pain
Diffuse, burning or aching pain carried by small less-myelinated axons
Referred pain
Pain perceived in a location different from the source
Cause of referred pain
Convergence of organ and skin inputs onto the same spinal neurons
Chronic pain
Persistent pain not directly linked to immediate tissue injury
Chronic pain causes
Arthritis, migraines, back pain, or unknown causes
Emotional effects of chronic pain
Depression, frustration, helplessness, hopelessness
Primary sensory areas
Cortical regions that receive sensory input
Primary somatic sensory cortex
Located in postcentral gyrus; processes touch, pressure, pain, temperature
Taste area
Located in the insula
Olfactory cortex
Located on inferior surface of temporal lobe; processes smell
Primary auditory cortex
Located in temporal lobe; processes hearing
Visual cortex
Located in occipital lobe; processes vision
Primary motor cortex
Controls voluntary movement; contains ~30% of upper motor neurons
Premotor area
Plans and organizes motor movements
Prefrontal area
Responsible for motivation, planning, emotional behavior, and mood
Working memory
Short-term storage used to perform immediate tasks
Short-term memory
Lasts minutes to days; involves long-term potentiation
Long-term memory
Lasts days to lifetime; involves consolidation
Consolidation
Process of strengthening synaptic connections to form long-term memory
Declarative (explicit) memory
Memory of facts; involves hippocampus and amygdala
Procedural (implicit) memory
Memory of skills; involves cerebellum and premotor area
Memory processing
Conversion of short-term memory into long-term memory
Long-term potentiation
Strengthening of synapses during memory formation
Protein synthesis in memory
Increases size and number of synaptic connections
Dendritic spikes
Structures where new synapses form during memory consolidation
Cytoskeleton changes
Structural neuron changes that make memory more permanent
Stimulus intensity encoding
Determined by frequency of action potentials
Cold stimulus example
Activates thermoreceptors
Olfaction receptor type
Primary receptor (generates action potentials)
Hearing receptor type
Secondary receptor (releases neurotransmitter)
Fading smell of perfume
Example of adaptation
Below-threshold stimulus
Produces receptor potential but no action potential
Proprioceptors location statement
False—associated with joints/tendons, not visceral organs
Secondary receptor communication
Does not directly send signals to brain (uses neuron)
Phasic vs tonic adaptation
Phasic receptors adapt faster than tonic receptors