Self Care Exam 1 Drugs

Decongestant indication

Treatment of stuffy nose and cough associated with post nasal drip

Decongestant MOA

Alpha adrenergic agonists vasoconstrict nasal blood vessels

Topical decongestants

Xylometazoline and oxymetazoline

Mixed-acting systemic decongestant

Pseudoephedrine

Direct-acting systemic decongestant

Phenylephrine

Antihistamine MOA

Compete with histamine at central and peripheral histamine1-receptor sites

Antihistamine indication

Treatment of allergic rhinitis symptoms

Intranasal steroid indication

Treatment of persistent allergic rhinitis symptoms

Intranasal steroid MOA

Inhibit inflammatory mediators (prostaglandins, kinins, histamines)

Nasacort Allergy 24 HR (IS) & age

Triamcinolone; 2-5

Flonase Sensimist Allergy Relief & age

Fluticasone furoate; 2-11

Nasonex 24 HR Allergy & age

Mometasone; 2-11

Flonase Allergy Relief & age

Fluticasone propionate; 4-11

Rhinocort Allergy Spray & age

Budesonide; 6-12

Lesser sedating 1st Gen Oral Antihistamine

Chlorpheniramine; Chlor-Trimeton

Most sedating 1st Gen Oral Antihistamine

Diphenhydramine; Benadryl

Lesser sedating 2nd Gen Oral Antihistamine Claritine

Loratidine

Lesser sedating 2nd Gen Oral Antihistamine Allegra

Fexofenadine

Potentially sedating 2nd Gen Oral Antihistamine Zyrtec

Cetirizine

Potentially sedating 2nd Gen Oral Antihistamine Xyzal

Levocetirizine

Intranasal Antihistamine

Azelastine; Astepro

Mast Cell Stabilizer indication

Prevention and treatment of allergic rhinitis symptoms

Mast Cell Stabilizer MOA

Protects mast cells from immune and non-immune mediated triggers preventing release

MCS product

Cromolyn sodium; NasalCrom

Antitussive indication

Suppression of nonproductive cough

Antitussive MOA

Works centrally by increasing cough threshold in brain

Systemic Antitussive equipotent with codeine

Dextromethorphan; Delsym

Gold standard Systemic Antitussive

Codeine

1st Gen antihistamine also used as a Systemic Antitussive

Diphenhydramine; Benadryl

1st gen antihistamine derivative used as a Systemic Antitussive

Chlophedianol only available as combination products

Topical Antitussive

Menthol and Camphor

Expectorant indication

Temporary relief of acute, ineffective productive cough

Expectorant MOA

Loosens and thins lower respiratory tract secretions

Expectorant Guaifenesin products

Mucinex and Robitussin

Local Anesthetic indication

Temporary relief of sore throat symptoms

Local Anesthetic MOA

Reversibly block nerve impulse transmission

Local Anesthetic Cepacol

Benzocaine

Local Anesthetic Sucrets

Dyclonine

Local Anesthetic Chloraseptic

Phenol

Demulcent indication

Temporary relief of sore throat symptoms and irritation

Demulcent MOA

Forms protective film in mouth and mucous membranes

Demulcent Luden’s

Pectin

Fever pharmacologic therapy

Acetaminophen, NSAIDS, salicylates

Acute migraine analgesics

Acetaminophen

Acute migraine Ergots

DHE nasal spray

Acute migraine NSAIDS

Aspirin, diclofenac, ibuprofen, naproxen

Acute migraine Combinations

Acetaminophen/aspirin/caffeine (Excedrin), sumatriptan/naproxen

Muscle/Joint Pain pharmacologic therapy

Systemic and topical analgesics, topical counterirritants