Suppository excipient table

alpha tocopherol

antiox suppositories

polysorbate 80

toughening agent

→ polysorbates also used as surfactant / emulsifier

propylene glycol

toughening agent and mold lubricant

castor oil

toughening agent

Sweet almond oil

toughening agent and eutectic agent (plasticizer)

1-10% silica gel

suspending agent

mineral oil

mold lubricant (for water sol bses)

Glycerin

mold lubricant (for oleaginous bases)

methyl cellulose

viscosity enhancing agent

colloidal silicon dioxide

viscosity enhancing agent

aluminum monostearate

viscosity enhancing agent

Lecithin

surfactant / emulsifier

sorbitan esters (span)

surfactant / emulsifier

polyoxyethylene stearates (polyoxyl)

surfactants / emulsifier

Liquid paraffin

eutectic agent (plasticizer)

-decreases the MP

white wax

solidifying agent (inc MP)

cetyl esters wax

solidifying agent (inc MP)

Beeswax

solidifying agent (inc MP)