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arteries carry blood which direction?
away from the heart
veins carry blood which direction?
toward the heart
pulmonary circuit
carries deoxygenated blood from heart to lungs, returning oxygenated blood back to the heart
systemic circuit
carries oxygenated blood from the heart to the body, returning deoxygenated blood to the heart
describe the different coverings of the heart & their function
fibrous pericardium : tough outer layer, protects heart
serous pericardium : parietal (lines fibroud layer), visceral (epicardium, covers heart surface
pericardial cavity : contains fluid to reduce friction
what are the three layers of the heart wall?
epicardium, myocardium, endocardium
epicardium
outer layer of the heart wall made of connective tissue that functions to protect the heart
myocardium
middle layer of the heart wall made of cardiac muscle that functions to contract the heart
endocardium
innermost layer of the heart wall made of endothelium that functions to line the heart
what are the four chambers of the heart? what direction do they pump blood?
right atrium: receives deoxygenated blood from the body and pumps blood to the right ventricle.
right ventricle: pumps blood to the lungs
left atrium: receives oxygenated blood from the lungs, pumps blood to the left ventricle
left ventricle: pumps blood to the body
where is the tricuspid valve located?
the right atrium flowing into the right ventricle
where is the bicuspid / mitral valve located?
left atrium flowing into the left ventricle
where is the pulmonary semilunar valve?
flow from the right ventricle to the pulmonary artery
where is the aortic semilunar valve?
flow from the left ventricle to the aorta
how is blood supplied to the heart?
the right and left coronary arteries branch from the aorta to supply the myocardium
systole
contraction
diastole
relaxation and filling
what are the events of the cardiac cycle?
1) atrial systole while ventricular diastole
2) ventricular systole while atrial diastole
3) both chambers relax briefly
what are the main characteristics of cardiac muscle cells?
intercalated discs - striated - single nucleus - involuntary - has t-tubule openings
what is the pacemaker of the heart’s cardiac conduction system?
SA node
cardiac conduction system
SA node (pacemaker)
atrial syncytium
junctional fibers
AV node
AV bundle
bundle branches
purkinje fibers
ventricular synctium
what movement does each wave of an ECG display?
P wave: atrial depolarization (just prior to contraction)
QRS complex: ventricular depolarization (just prior to contraction)
T wave: ventricular repolarization (just prior to relaxation)
the “lubb” sound of the heart is a result of which valves closing and what movement is happening?
AV valves, ventricular systole
the “dubb” sound of the heart is a result of which vales closing and what movement is happening?
the pulmonary and aortic semilunar valves close. occurs during the ventricular diastole
how does the ECG correlate to heart sounds?
QRS: ventricular contraction → “lubb”
T wave: ventricular relaxation → “dubb”
during systole of each chamber type, does pressure increase or decrease?
increase
how do valves open and close?
pressure differences
heart rate changes occur due to factors that influence the __________
SA node
parasympathetic impulses reach the heart through which nerve?
Vagus
does the parasympathetic system increase or decrease heart rate? sympathetic system?
parasympathetic: decrease
sympathetic: increase
through which type of nerve do sympathetic impulses reach the heart?
accelerator nerves
baroreceptor reflex
maintaining blood
cardioinhibitory reflex
lowers heart rate and blood pressure
cardioaccelerator reflex
increases heart rate and force of contraction to lower venous pressure
what are the types of blood vessels?
arteries, arterioles, capillaries, venules, veins
arteries - describe & list function(s)
thick, strong walls. transport blood under high pressure and give rise to smaller arterioles
what are the three layers of arteries?
tunica interna, tunica media, tunica externa
metarterioles
branches that join capillaries or veins
does vasoconstriction result from a stimulation or an inhibition of the vasomotor impulse?
stimulation
capillary - describe and give function(s)
smallest diameter blood vessel that connects arterioles to smallest venules. extensions of inner linings of arterioles, semipermeable layer through which substances in the blood are exchanged for substances in the tissue fluid
fenestrated capillary
“leaky” : glands secrete through holes
sinusoidal capillary
found in the liver, spleen, and bone marrow, there are large cavities in the capillary and there is an incomplete basement membrane
list some differences between veins and arteries
arteries have high pressure, veins have low pressure. arteries have thick walls, veins have thin walls. arteries do not have valves, veins have valves
how do valves ensure blood returns to the heart?
they prevent backflow and work with muscle contractions
blood pressure
force the blood exerts against the inner walls of the blood vessels
systolic pressure
maximum pressure achieved during ventricular contraction
diastolic pressure
lowest pressure remaining in arteries during ventricular relaxation
what factors influence BP?
blood volume, heart rate, stroke volume, blood viscosity, peripheral resistance
how do you calculate cardiac output?
multiplying heart rate by stroke volume
CO = SV x HR
stroke volume
amount of blood discharged with each heartbeat, typically around 70 mL
cardiac output
amount of blood discharged from ventricle per minute
peripheral resistance
force of friction between blood and the walls of blood vessels
how to calculate blood pressure?
product of cardiac output and peripheral resistance
BP = CO x PR
Frank-Starling Law of the Heart
more ventricular filling leads to a stronger contraction