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What are the pairs called that chromosomes come in
homologous pairs (one from each parent)
what does homologous pairing mean and what does this mean fro the chromosome
they carry the same genes as each other, but there are slight variations in each gene
alleles
the matched genes that code for the same protein
sex chromosomes are more different from each other compared to what
homologous pairs of autosomes
meiosis involves
two divisions, yielding 4 daughter cells with the ½ the chromosomes of the parent cell
what does sexual reproduction allow for
genetic variation between each generation
what does genetic variation allow for
adaptation to changes in environmental conditions
flexibility
ploidy
the number of sets of chromosomes
humans are mostly….
diploid (2 sets)
though human gametes are…
haploid (1 set)
many plants and non-mammalian vertebrates are….
tetraploid (4 sets)
ploidy can vary over…
organisms life cycle
between different cell types within an organism
multiples of the same chromosomes are called
homologous chromosomes
meiosis 1:
parent cells is diploid (2n) and contains a homologous pair of replicated chromosomes
meiosis 2:
daughter cells are haploid (n) and contain just one homolog
four daughter cells contain…
one unreplicated chromosome each
in animals, the four haploid daughter cells in meiosis can develop into what?
gametes
what does meiosis give a diploid organism
haploid gametes
in order to reproduce we must combine what?
two gametes in order to reconstitute a full genome
diploid offspring contains what
homologous pair of chromosomes
meiosis I
interphase (uncondensed chromosomes replicate in parent cell)
early prophase I
late prophase I
metaphase I
anaphase I
meiosis II
telophase I
prophase II
metaphase II
anaphase II
telophase II
meiosis I: interphase
prepare for cell division
synthesis happens as normal, replicating the genome
what are the two distinctions from prophase in mitosis vs prophase in meiosis
in meiosis, with early prophase I, it involves pairing of homologous chromosomes (synapsis)
in meiosis with late prophase I, non-sister chromatids begin to separate but remain joined at some points
chiasma
the points where the chromatid are still joined
what happens at chiasmata
the chromosomes break and exchange pieces which is called crossing over
summary of prophase
replication during interphase
synapsis, during prophase I
crossing over, during prophase I
synapsis
the pairing of homologous chromosomes
what does early prophase I of meiosis form
tetrads or bivalents which are two pairs of sister chromatids
what are the chromatids from different homologous chromosomes called
non-sister chromatids
crossing over usually occurs
at least once in each non-sister chromatid
meiosis I: metaphase I
each tetrad moves to the metaphase plate, half as many tetrads lined up compared to mitosis due to the pairing, which doesn’t happen in mitosis as they line up individually
how many tetrads are lined up during meiosis I metaphase
23 tetrads (each = 2 chromosomes)
what is the orientation like for each tetrad in meiosis I: metaphase I
each tetrad is random
each tetrad in meiosis I: metaphase I has a 50/50 chance of…
having the maternal or paternal chromosome on a particular side
meiosis I: anaphase I
each tetrad is pulled apart and moved to opposite sides of the cell
sister chromatids from each maternal or paternal chromosome stay together, but are not identical anymore as they carry new combos of genetic material
meiosis I: telophase I
homologous chromosomes move to opposite sides
meiosis I: cytokinesis I
finished meiosis I
yields two haploid cells (CHROMOSOMES ARE STILL REPLICATED)
meiosis II
two daughter cells now proceed thru all of the phases of meiosis (except just no prophase)
in mitosis:
46 replicated chromosomes are split, yielding 2 daughter cells w/ 46 unreplicated chromosomes
in meiosis I:
23 tetrads are split, yielding 2 daughter cells with 23 replicated chromosomes each
meiosis II:
23 replicated chromosomes are split (in each daughter cell), yielding 4 daughter cells w/ 23 unreplicated chromosomes each
nondisjunction
the failure of either homologous chromosomes (meiosis I) ir sister chromatids (meiosis II) to separate
nondisjunction leads to…
some daughter cells w/ too many and some w/ too few chromosomes
daughter cells getting too many chromosomes is called
trisomy
daughter cells getting too few chromosomes is called
monosomy
errors in meiosis happens to how many of all human zygotes?
1/3
aneuploid cells
cells with an incorrect number of chromosomes
cancer is a common result in cells that what
lose the ability to correct errors in DNA replication + to prevent mitosis w/ checkpoints
which is slower asexual or sexual reproduction?
sexual reproduction