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metronidazole
avoid alcohol or propylene-glycol containing products
causes darkened urine, metallic taste
-statins
may cause myopathy or rhabdomyolysis,
(do not use in pregnancy, lactation, liver disease),
avoid grapefruit juice
beta-blockers
may cause bradycardia, fatigue, hypotension
do not stop suddenly, taper over 12 weeks
ACE inhibitors
causes dry cough, hyperkalemia
do not take with ARBs or ARNIs
BBW: fetal harm and death
ketoconazole
shampoo may alter hair structure and texture
cephalosporins
cross-sensitivity with penicillin allergy
may cause serious skin reactions
fluoroquinolone antibiotics
increased risk of seizure
(BBW: tendon inflammation, CNS effects,
separate from nonvalent cations,
avoid in pregnancy and lactation)
Nitrostat
keep in its original amber container and at room temp
(do not use with PDE-5 inhibitors)
propranolol
non-selective so it can be used for migraine prophylaxis
labetalol
is the choice for HTN treatment in pregnancy
warfarin
may cause purple toe syndrome, (tissue necrosis, skin bruising
do not take when pregnant)
Pradaxa
swallow the capsules whole, must be kept in its original container
loop diuretics
avoid use with NSAIDs, take in the morning to prevent leaking, sulfa allergy cross sensitivity
(can cause alkalosis)
diuretics in general
depletes electrolytes
potassium sparing diuretics
increase risk of hyperkalemia
Enoxaparin
comes as a pre-filled syringe, do not expel air bubble from syringe prior injection
CaroSpir
causes gynecomastia, hyperkalemia, breast tenderness
interacts with lithium
ACE inhibitors (all)
Common Indications: Hypertension, heart failure
BBW: Fetal harm and death (avoid in pregnancy)
Contraindications: History of angioedema, Do not use within 36 hours of Entresto (valsartan/sacubitril).
Warnings/Precautions: Angioedema, hyperkalemia, hypotension, renal impairment, avoid use if bilateral renal artery stenosis
Side Effects: Dry cough, hyperkalemia, increase in SCr, hypotension, dizziness
Drug Interactions: Do not use in combination with ARBs or ARNI. Increased risk of lithium toxicity.
Counseling points: Avoid salt substitutes containing potassium
clonidine
do not D/C suddenly or risk rebound hypertension
patch may cause skin reaction
cordarone
avoid grapefruit juice
Tambocor
may cause visual disturbances, dyspnea
(BBW: proarrhythmic effects)
Cardura
causes ghost tablet in stool
doxycyline
take with water and sit upright for at least 30 min after
Tamiflu
is the most effective when taken within 48 hours
(neuropsychiatric or skin reactions may occur)
chlorhexidine gluconate
may cause teeth discoloration
nitrofurantoin
warning: hemolytic anemia
(do not use in renal impairment, may cause brown urine concentration)
-triptans
take for migraines, every 2 hour needed
Scopolamine
if you accidentally touch your eyes it may stinging
valproic acid
increases lamotrigine lvels
Dilantin
causes heair growth
Sinemet
don’t take within 14 days of MAOi, may cause dark urine or hallucinations o
opioids
may cause constipation m
MS Contin
may cause severe itching
NSAIDs
they can increase the risk of bleeding
Ketorolac
can only take for 5 days maz
SSRIs
(/most antidepressants) increased risk of security
Pristiq
may cause ghost tablet in stool
Namenda
can be sprinkled into opposites
acne drugs
avoid in pregnancy
Metformin
causes vitamin-B 12 deficiency, ER formulation may contribute to this
SGLTs
acute-kidney injury
bisphosphonates
polyvalent cations, take 30 min before food
birth controls
take the same time every day
PPIs
increased risk of osteoporosis, may need to give vitamin C and D supplements
Ditropan
avoid mouthwashes that contain alcohol
Pyridium
discolors the urine to red-orange color s
sulfasalazine
causes yellow-orange skin discoloration
folic acid
can decrease risk of neural tube defects
Lovaza
use with caution in shellfish hypersnsitiivty
prostaglandins
darkening of the iris and lengthening of the eyelashes
respiratory drugs
know which ones need to be shaken before use (priming it)
corticosteroids
know which one to rinse your mouth after
varenicline
begin use on week prior stop hate
tetracycline
separate from antacids and polyvalent cations (at least 1-2 hours prior or 4 hours after chlelating drug);
may cause permanent teeth discoloration in pregnant/lactating women, in pt < 8 yrs