1/3 Insulin and Mrs. Barlow's Bathtub

When was the idea of a chemical being both toxic and tonic appreciated?

The medical revolution during the renaissance.

Who is the sixteenth century alchemist and physician that cautioned “It is the dose that makes the poison.”?

Philippus Aureolus Theophrastus Bombastus Von Hohenheim (AKA Paracelsus)

What is the scientific name for diabetes?

Diabetes Mellitus.

Diabetes as a death sentence before insulin. What American doctors advocated severe fasting to prolong the lives of diabetic patients?

Fredrick Allen and Elliott Joslin.

What year did Canadian researchers manage to identify and purify insulin from animal pancreases?

1921

Who was the first patient treated with insulin?

14 year old, Leonard Thompson.

When did commercial insulin become available?

1923

What was the name of the detective that was called to investigate Elizabeth Barrlow's death?

Detective Sergeant John Naylor.

When and where did the detective that investigated Elizabeth Barlow's death arrive?

He arrived to the house on Thornbury Crecent in Bradford, England. He arrived in the early hours of Saturday, May 4 1957.

What was the names of the “happy” couple involved in the murder.

Elizabeth “Betty” Barlow and Kenneth Barlow.

What year did Elizabeth and Kenneth get married?

1956 following the death of Kenneth’s first wife

What was the name of Kenneth’s son and Elizabeth’s stepson?

Ian Barlow

What were Kenneth and Elizabeth’s careers?

Kenneth was a state registered nurse and Elizabeth was an auxiliary nurse, working in different hospitals around Yorkshire, Bradford. After the wedding Elizabeth left nursing and took a job in the ironing section of a local laundry.

What date did the murder take place?

May 3, 1957

On the way home, Elizabeth picked up some fish and chips. What time did they begin eating?

12:30

What time did Elizabeth visit her neighbor, Mr Skinner?

Four o’clock

After feeling sick and restless, Elizabeth went to take a nap. What time did Elizabeth go to take a nap and what did she ask of Kenneth?

At 6:30 and she asked him to come and get her in an hour to watch a program.

What time did Elizabeth call for Kenneth and What did he find when he entered the bedroom?

Shortly after nine thirty. He found that she had vomited on their bed.

What time did Elizabeth tell Kenneth that she was going to take a bath?

Ten o’clock

What time did Kenneth Barlow wake to find that Elizabeth wasn’t in bed?

11:20 p.m.

When the paramedics found Elizabeth dead in the bathtub, what was the first sign of suspicious activity?

Her pupils were too dilated for a drowning victim.

Why are sugars known chemically as carbohydrates?

They are made carbon, hydrogen, and oxygen atoms linked together in particular ways.

How many carbon, hydrogen, and oxygen atoms are in the smallest sugars?

6 carbon and oxygen atoms and 12 hydrogen atoms. C6H12O6.

Depending on the arrangement of C6H12O6, what three sugars can be made?

Fructose (fruit sugar), galactose (found in foods like milk and avocados), and glucose.

What is another term for Glucose?

“blood sugar”

What is the proper name for table sugar and how is it made?

Sucrose. Its made by joining a molecule each of fructose and glucose.

What is another term for milk sugar and how is it made?

Lactose. Its made by joining glucose and galactose molecules.

What does linking hundreds and thousands of carbon, hydrogen, and oxygen atoms together in a long chain form?

Glycogen in animals or starch and fiber in plants.

When carbohydrates are broken down into the three sugars (glucose, galactose, and fructose) where do they get shipped off to?

The liver.

What is it called when there is to little glucose in the blood?

Hypoglycemia